Photo by PhotoJoy
Luxury Hotels in Panama
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama Luxury Hotels
Our top choices for Panama luxury hotels
9.0 out of 10, Wonderful, (1,002 reviews)
- Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
"The ocean view from the infinite pool is amazing."
Charmaine Marie
The price is S$359
includes taxes & fees
19 Jun - 20 Jun
9.4 out of 10, Exceptional, (1,000 reviews)
- Art deco elegance meets modern luxury in this Panama City hotel featuring 2 bars, a full-service spa, and an outdoor pool.
"Although I did not get a spa service or treatment during my short stay, I did go up to the area just to check it out and I was greeted very warmly and the services were explained to me."
Kimberly
The price is S$293
includes taxes & fees
10 Jun - 11 Jun
9.0 out of 10, Wonderful, (1,000 reviews)
- Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
"Luxury in Panama"
Kelinde
The price is S$357
includes taxes & fees
19 Jun - 20 Jun
9.4 out of 10, Exceptional, (740 reviews)
- A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalised service in a historic district.
"Very vintage and luxurious"
haim
The price is S$366
includes taxes & fees
5 Jun - 6 Jun
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by MarriottBella Vista
8.8 out of 10, Excellent, (1,000 reviews)
- Indulge in Panama City luxury with an outdoor pool, full-service spa, and casino at this stylish hotel near Via Espana.
"Great spa"
Robert
The price is S$252
includes taxes & fees
31 May - 1 Jun
9.0 out of 10, Wonderful, (1,001 reviews)
- Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
"April 2026 — Luxury, romance, and family comfort with incredible bay views (and excellent accessibility)"
Annie
The price is S$321
includes taxes & fees
7 Jun - 8 Jun
8.4 out of 10, Very good, (1,000 reviews)
- Indulgent pampering awaits at this Beaux Arts Panama City gem with spa, casino, and rooftop bar.
"Beautiful views"
Sofi
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
The Buenaventura Golf & Beach Resort Panama, Autograph CollectionEl Chiru
9.2 out of 10, Wonderful, (748 reviews)
- Immerse in beachfront opulence with 12 stunning pools, a full-service spa, and private beach access at this Panama golf resort.
"The room was spacious, comfortable, and luxurious."
Donna
The price is S$280
includes taxes & fees
3 Jun - 4 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Panama Hotel Reviews
Crowne Plaza Panama Airport by IHG
10/10 Excellent
Explore a world of travel with Expedia
- 5 Star Hotels in Mechi
- 5 Star Hotels in Panama City
- Gay friendly Hotels in Ancon
- Atalaya Hotels
- Hotels with Bars / Lounges in Boca Chica
- Boca Corona Hotels
- Gay friendly Hotels in Bocas del Toro
- Guest Houses in Bocas del Toro Province
- Boquete Hotels
- Buena Vista Hotels
- Campana Hotels
- Gay friendly Hotels in Cerro Azul
- Cerro Punta Hotels
- Golf Hotels in Chitre
- Hotels with Swimming Pools in Chitre
- Coco Key Hotels
- Colon Hotels
- Gay friendly Hotels in David
- David Hotels
- All Inclusive Hotels and Resorts in Bocas del Toro Province
- Bocas del Toro Province Hotels
- Gay friendly Hotels in Bugaba
- Bugaba Hotels
- Gay friendly Hotels in Chiriquí Province
- Chiriquí Province Hotels
- Colón Hotels
- Darién Province Hotels
- Beach Resorts in Guna Yala
- Guna Yala Hotels
- Beach Resorts in Los Santos
- Casino Hotels in Los Santos
- Hotels with Airport Shuttle in Los Santos
- Panamá Oeste Province Hotels
- Panamá Province Hotels
- Beach Resorts in Veraguas
- Dolega Hotels
- Gay friendly Hotels in El Chiru
- El Valle de Anton Hotels
- Hotels with Restaurants in Gamboa
- La Arena Hotels
- La Loma Hotels
- Mechi Hotels
- Narganá Hotels
- All Inclusive Hotels and Resorts in Panama City
- Beach Resorts in Panama City
- Boutique Hotels in Panama City
- Budget Hotels in Panama City
- Casino Hotels in Panama City
- Four Seasons Hotels in Panama City
- Gay friendly Hotels in Panama City
- Hotels with Airport Shuttle in Panama City
- Hotels with Balcony in Panama City
- Hotels with Bars / Lounges in Panama City
- Hotels with Breakfast in Panama City
- Hotels with Gyms in Panama City
- Hotels with parking in Panama City
- Hotels with Swimming Pools in Panama City
- Hotels with smoking rooms in Panama City
- Hotels with Views in Panama City
- Loews Hotels in Panama City
- Pet friendly Hotels in Panama City
- Romantic Hotels in Panama City
- Hotels near Shopping Areas in Panama City
- Sonesta Hotel in Panama City
- Hotels with Spa in Panama City
- Gay friendly Hotels in Paraiso
- Paraiso Hotels
- Pedasí Hotels
- Hotels with smoking rooms in Playa Coronado
- San Blas Islands Hotels
- Hotels with Yoga in Santa Catalina
- Gay friendly Hotels in Santa Clara
- Sorá Hotels
- Resorts in Sorá
- Torio Hotels
- Veracruz Hotels