
Panama Holidays
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Panama Flight & Hotel Packages

San Francisco by Wynwood House
Reviewed on 11 Sept, 2025

Las Americas Golden Tower Panama
Reviewed on 26 Sept, 2025

Megapolis Hotel Panamá
Reviewed on 27 Sept, 2025

Riande Aeropuerto Hotel & Casino
Reviewed on 26 Sept, 2025

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Reviewed on 25 Sept, 2025
Panama Holiday
While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.
Panama Hotel + Flights
Expedia has 3,334 hotels available here starting at S$168 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Holiday Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?
Your Panama Holiday Itinerary
Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.
Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.
Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.
Panama Information
Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.
If you’ll be spending most of your time in the nation’s capital, check out our Panama City Holiday PackagesOpens in a new window.
Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to holiday planning stress.
Top hotels in Panama

Hotel Riu Plaza Panama
Reviewed on 25 Sept, 2025

Dreams Playa Bonita Panama - All Inclusive
Reviewed on 26 Sept, 2025

Crowne Plaza Panama Airport by IHG
Reviewed on 25 Sept, 2025
Frequently asked questions
Popular places to visit
Colon Free Zone
During your trip to Colon, you can do some window-shopping at Colon Free Zone.
What to do in Panama

Panama City Visit an Indian town Embera and waterfall with lunch

Tour Waterfall and Embera village with lunch and entry included

Panama Canal Monkey & Wildlife Boat Safari
More trip options
Expedia's Latest Trends
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.