Regis is a neighbourhood that travellers like for its jazz scene, golf courses and university setting. Are you looking for Regis travel tips? Make sure that you visit Clear Creek and Willis Case Golf Course while you're in the neighbourhood.

Where is the best hotel for a stay in Regis?

For your stay in Regis, Motel 6 Denver, CO – Downtown is one of the top choices based on our traveller data.

How many hotels will I be able to find in Regis?

Book one of Expedia's 7 hotels and other accommodation options in Regis and start exploring everything Denver has to offer.

If I need to cancel my hotel reservation in Regis, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best options available in Regis.

What can I see and do in this Denver neighbourhood?

A few attractions you might want to check out while you're in Regis are Clear Creek and Willis Case Golf Course. While you're out sightseeing in Denver, make sure that you visit other sights such as William Scheitler Recreation Center or The Oriental Theater.

Top 10 Regis Hotels of 2026 | Expedia Singapore

A large, historic building with a prominent clock tower and a statue in front.

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Our top choices for Regis hotels

A modern hotel with a prominent '6' sign, multiple floors, and a parking lot with several cars.

1. Motel 6 Denver, CO – Downtown

Regis

Otilia

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a desk, a chair, and a view of the outdoor patio.

2. Holiday Inn Express Denver Central North by IHG

5.5 km from Regis

Armonia

includes taxes & fees

2 Nov - 3 Nov

A modern hotel with a prominent sign, multiple floors, and a parking sign visible.

3. Home2 Suites by Hilton Denver Downtown Convention Center

Downtown Denver, 6.4 km from Regis

Michael

includes taxes & fees

3 Oct - 4 Oct

A swimming pool with inflatable toys, lounge chairs, and a mural on the wall.

4. Hampton Inn & Suites Denver-Downtown

Uptown, 6.9 km from Regis

Joshua S

includes taxes & fees

2 Nov - 3 Nov

A spacious restaurant with high ceilings, large windows, and a variety of seating options including tables and booths.

5. Hilton Garden Inn Denver Union Station, CO

LoDo, 5.1 km from Regis

Corey

includes taxes & fees

2 Nov - 3 Nov

A bar area with a long counter, multiple stools, a television mounted on the wall, and a sign indicating a maximum occupancy of 166.

6. Vīb Hotel by Best Western Denver RiNo

River North Art District, 6 km from Regis

Karah

includes taxes & fees

1 Nov - 2 Nov

A modern lobby with a wooden ceiling, large windows, a seating area with sofas and ottomans, and a reception desk.

7. Cambria Hotel Denver Downtown RiNo

River North Art District, 5.9 km from Regis

Jesus

includes taxes & fees

25 Oct - 26 Oct

A bar area with wooden chairs, a counter with bottles, and pendant lights.

8. Hyatt Place Denver Downtown

Downtown Denver, 6.7 km from Regis

Blaine

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with a large arched window, a leather sofa, two potted plants, and a bicycle mounted on the wall.

9. Origin Westminster a Wyndham Hotel

8 km from Regis

Maria

includes taxes & fees

4 Oct - 5 Oct

A rooftop bar with outdoor seating, a bar counter, and a fire feature.

10. AC Hotel by Marriott Denver Downtown

Downtown Denver, 6.4 km from Regis

Ashley Dian Wahlfeldt

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with stainless steel appliances, wooden flooring, and a brick wall.

11. Catbird Hotel

6.4 km from Regis

Susanna

includes taxes & fees

25 Oct - 26 Oct

A bar with a view of a cityscape, including a prominent building with a dome.

12. Populus

Downtown Denver, 6.9 km from Regis

Valeria

includes taxes & fees

31 Oct - 1 Nov

A couple seated on a leather couch with a cityscape view through large windows.

13. Hyatt Regency Denver at Colorado Convention Center

Downtown Denver, 6.5 km from Regis

Lesley

includes taxes & fees

3 Oct - 4 Oct

A modern restaurant with a central bar area, multiple seating options, and a contemporary interior design.

14. Hyatt Centric Downtown Denver

Downtown Denver, 6.3 km from Regis

Rigel

includes taxes & fees

4 Oct - 5 Oct

A lobby with a marble floor, a central staircase, and a reception desk.

15. Hotel Teatro

Downtown Denver, 6 km from Regis

Diana

includes taxes & fees

2 Nov - 3 Nov

A modern dining area with long communal tables, chairs, and a long counter.

16. Element by Marriott Denver Downtown East

7 km from Regis

Ivan O Torres

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a stone fireplace, geometric shelving, and patterned armchairs.

17. Renaissance Denver Hotel & Conference Center

12.1 km from Regis

Shericka

includes taxes & fees

9 Oct - 10 Oct

A Hilton hotel entrance with a glass facade, illuminated signage, and a modern architectural design.

18. Hilton Denver City Center

Downtown Denver, 6.5 km from Regis

Kyrell

includes taxes & fees

25 Oct - 26 Oct

A modern hotel with a prominent 'SONESTA' sign, surrounded by other high-rise buildings and a well-lit urban street at dusk.

19. Sonesta Denver Downtown

Downtown Denver, 6.7 km from Regis

Melanie

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, large windows, and a central seating area with blue chairs and a round table.

20. Magnolia Hotel Denver, A Tribute Portfolio Hotel

Downtown Denver, 6.3 km from Regis

Yuke

includes taxes & fees

25 Oct - 26 Oct

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Where to stay in Regis

Find the best Regis areas for the activities you enjoy most.

A modern architectural complex with geometric shapes and a prominent red sculpture.

Downtown Denver

Discover Denver is at its most dynamic in this central district, which has cool craft breweries, bars, galleries, boutiques and entertainment venues.

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A city street with a large canopy structure, modern buildings, and potted plants.

Cherry Creek

Abundant dining options and stunning river views are well-reviewed features of Cherry Creek. Make a stop by top sights like Cherry Creek Shopping Center while you're exploring the area.

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A cityscape with modern buildings and a forested area in the foreground.

Denver Tech Center

Known for its ample dining options and great live music, there's plenty to explore in Denver Tech Center. You can visit top attractions like Fiddler's Green Amphitheatre and The Landmark Theatre Greenwood Village, and jump on the metro at Orchard Station or Arapahoe at Village Center Station to see more of the city.

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A brightly lit train station with a large Christmas tree and illuminated decorations.

LoDo

Visitors often come to LoDo for its abundant dining options, but many stay to explore sights like Union Station and McGregor Square. Getting around the area on the metro is easy if you take a ride at Union Station-Coors Field-16th St. Mall Station.

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A rural landscape with a field of corn, a bridge, and houses in the background.

Highlands Ranch

Highlands Ranch is known for its abundant dining options, and you can plan a trip to South Suburban Sports Complex and Chatfield State Park while you're in town.

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Top Regis Hotel Reviews

Hyatt Place Peña Station/Denver Airport

8/10 Good

"Great hotel close to Denver airport. Easy check-in/out. Close to plenty of good restaurants. The airport shuttle was a nice amenity. Comfortable beds and clean room. The only minor inconvenience was a loud air conditioning unit. Has my recommendation and would definitely stay here again."

Holiday Inn Express Denver Downtown by IHG

10/10 Excellent

"The hotel location is great, only one block away from the 16th Street FreeRide buses that bring you from Union Station into downtown Denver. Being so close to restaurants and shops on 16th Street was very convenient. Also just a short walk to the convention center. The check-in went smoothly, very courteous staff who actually allowed me to check in early and gave me some information about the area. The hotel and the room were both very clean and welcoming. The beds were extremely comfortable. The breakfast was very good, and the staff made sure the area was well stocked, serviced and clean. Small note, there are two machines that makes the coffee from fresh beans; it was delicious, and available at all times. I will definitely book a room here the next time I travel to Denver."

Hotels in Regis

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Our top choices for Regis hotels

1. Motel 6 Denver, CO – Downtown

2. Holiday Inn Express Denver Central North by IHG

3. Home2 Suites by Hilton Denver Downtown Convention Center

4. Hampton Inn & Suites Denver-Downtown

5. Hilton Garden Inn Denver Union Station, CO

6. Vīb Hotel by Best Western Denver RiNo

7. Cambria Hotel Denver Downtown RiNo

8. Hyatt Place Denver Downtown

9. Origin Westminster a Wyndham Hotel

10. AC Hotel by Marriott Denver Downtown

11. Catbird Hotel

12. Populus

13. Hyatt Regency Denver at Colorado Convention Center

14. Hyatt Centric Downtown Denver

15. Hotel Teatro

16. Element by Marriott Denver Downtown East

17. Renaissance Denver Hotel & Conference Center

18. Hilton Denver City Center

19. Sonesta Denver Downtown

20. Magnolia Hotel Denver, A Tribute Portfolio Hotel

Where to stay in Regis

Downtown Denver

Cherry Creek

Denver Tech Center

LoDo

Highlands Ranch

Top Regis Hotel Reviews

Hyatt Place Peña Station/Denver Airport

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