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Domus 21 Luxury Suites

Travelers find a genuine Roman home base at Domus 21 Luxury Suites, where express check-in and coworking spaces complement easy access to Campo de' Fiori

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Located in central Rome, Domus 21 Luxury Suites welcomes families with practical comforts. The property offers pet-sitting services, coworking areas with reliable in-room WiFi, and express check-in/out. Guests consistently praise the attentive staff.
VIP Access

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Laundry room
  • Housekeeping

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Room options

Available filters for rooms
Showing 4 of 4 rooms

View all photos for Superior Room, 1 Queen Bed, Courtyard View

Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Superior Room, 1 Queen Bed, Courtyard View

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Soundproofed
Individually furnished
Individually decorated
Air conditioning
Connecting rooms available
Free cots/infant beds
Minibar (some free items)
  • 20 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 Queen Bed

View all photos for Deluxe Room, City View

View from room

Deluxe Room, City View

9.6 out of 10
Exceptional
(4 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cots/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
  • City view
  • 24 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed OR 2 Single Beds

View all photos for Junior Suite

Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Junior Suite

10.0 out of 10
Exceptional
(3 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cots/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
  • City view
  • 40 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Grand Room

Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Grand Room

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cots/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
  • City view
  • 34 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

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About the area

Located in Rome City Centre neighbourhood, Domus 21 Luxury Suites is connected to a railway/underground station. Vatican Museums and Castel Sant'Angelo are cultural highlights, and travellers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Make sure you don't miss outdoor adventures like mountain climbing, ecotours and ziplining, or hop on a segway for hire nearby and take a self-guided tour around Rome. Visit our Rome travel guide
View more Guest houses in Rome
Map
Corso Vittorio Emanuele II 21, Rome, RM, 00186

What's nearby

  • Area Sacra di Largo Argentina showing heritage elements and building ruins
    Largo di Torre Argentina
    2 min walk - 0.2 km
  • Teatro Faiano
    1 min walk - 0.0 km
  • Piazza della Minerva
    2 min walk - 0.2 km
  • Santa Maria Sopra Minerva
    2 min walk - 0.2 km
  • Chiesa del Gesù
    2 min walk - 0.2 km

Getting around

  • Venezia Tram Stop
    4 min walk
  • Rome San Pietro Station
    5 min drive
  • Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)
    40 min drive

Restaurants

  • Alice Pizza Largo Argentina
    1 min walk
  • Shari Vari
    5 min walk
  • Te Amo
    5 min walk
  • PASTAEAT la pastapoke
    1 min walk
  • Appetito Cafe
    5 min walk

About this property

Domus 21 Luxury Suites

Luxury family-friendly guest house near Pantheon
A short walk from Campo de' Fiori and Piazza Navona, Domus 21 Luxury Suites provides dry cleaning/laundry services and more. Guests can connect to free in-room WiFi.
Other perks include:
  • A round-trip airport shuttle (surcharge), an electric car charging station and express check-out
  • Express check-in, books and bike parking
  • Smoke-free property, a lift and coworking spaces
  • Guest reviews speak highly of the helpful staff
Room features
All guest rooms at Domus 21 Luxury Suites have comforts, such as premium bedding and pillow menus, in addition to thoughtful touches, such as laptop-compatible safes and air conditioning.
More amenities include:
  • Highchairs, children's books and art supplies
  • Reusable coffee/tea filters, recycling and LED light bulbs
  • Rainfall showers, designer toiletries and bidets
  • Composting, eco-friendly cleaning products and childcare services

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • In-room WiFi speed: 500+ Mbps (good for 6+ people or 10+ devices)
  • Available in some public areas: Free WiFi

Parking and transport

  • Electric car charging station on site
  • Offsite parking available (EUR 24 per day); discounts available
  • Street parking available
  • 24-hour return airport shuttle at scheduled times and on request for a surcharge

Food and drink

  • Couples/private dining
  • Private picnics

Things to do

  • Bicycle tours
  • Books
  • Helicopter/aeroplane tours
  • Private wine tours
  • Wine tours
  • Winery release events

Family friendly

  • Art supplies
  • Baby toys
  • Children's books
  • Children's games
  • Children's toys
  • High chair
  • In-room babysitting
  • In-room cot
  • Laundry facilities
  • Soundproofed rooms

Conveniences

  • Free newspapers in lobby
  • Guidebooks
  • Laundry facilities
  • Limited-hour front desk
  • Luggage storage

Guest services

  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Proposal/romance packages
  • Tour and ticket assistance
  • Turndown service

Business services

  • Coworking space

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible airport shuttle
  • Lift
  • Well-lit path to entrance

More

  • At least 10% of profits reinvested in community and sustainability
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Comprehensive recycling policy
  • Double-glazed windows
  • Humane treatment of captive wild animals
  • Local artist showcase
  • Local culture and ecosystem education
  • Locally-owned and organised tours and activities
  • Smoke-free property

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Egyptian cotton sheets
  • Free cot
  • Hypo-allergenic bedding
  • Pillow menu
  • Pillowtop mattress

Bathroom

  • Bidet
  • Designer toiletries
  • Dressing gowns
  • Hair dryer
  • Rainfall showerhead
  • Shampoo
  • Shower
  • Slippers
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Champagne service
  • Coffee/tea maker
  • Electric kettle
  • Espresso maker
  • Free bottled water
  • Free minibar (limited items)
  • Restaurant dining guides

More

  • Air conditioning
  • Cleaning products are eco-friendly
  • Composting
  • Connecting rooms available
  • Eco-friendly toiletries
  • Electrical adapters
  • Energy-saving switches in guestrooms
  • Free daily newspapers
  • Iron/ironing board on request
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Printer
  • Recycling
  • Reusable coffee/tea filters
  • Soundproofed rooms
  • Water-efficient showers
  • Water-efficient toilets

Policies

Check-in

Check-in start time: 2:00 PM; check-in end time: 11:30 AM
Contactless check-in and check-out are available
Express check-in available
Minimum check-in age - 15

Check-out

Check-out before 11:30 AM
Contactless check-out
Express check-out available

Special check-in instructions

This property offers transfers from the airport (surcharges may apply); guests must contact the property with arrival details before travel, using the contact information on the booking confirmation
The front desk is open daily from 9:00 AM - 5:00 PM
Guests planning to arrive outside of normal check-in hours must contact the property in advance for check-in instructions and key retrieval information; front desk staffed during limited hours
To make arrangements for check-in please contact the property at least 24 hours before arrival using the information on the booking confirmation
If you are planning to arrive after 2:00 PM please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Front desk (limited hours), key retrieval

Pets

Pets stay for free
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
4 total (up to 10 kg per pet)
Pets cannot be left unattended
Food and water bowls, pet-sitting services, litter trays and pet-grooming services are available

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Free cots are available on request at the property

Payment types at the property

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • A tax is imposed by the city: EUR 5.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

We have included all charges provided to us by the property.

Optional extras

  • Airport shuttle fee: EUR 70 per vehicle (one-way, maximum occupancy 2)
  • Airport shuttle fee per child: EUR 70 (one-way), (from 10 to 18 years old)
  • Nearby parking fee: EUR 24 per day (3281 ft away)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards and cash
Cashless transactions are available
Safety features at this property include a fire extinguisher, a security system, a first aid kit and window guards
Property Registration Number IT058091B4OUIRD7WF

We should mention

All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using the information in the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation

Property is also known as

Domus 21 Luxury Suites Rome
Domus 21 Luxury Suites Guesthouse
Domus 21 Luxury Suites Guesthouse Rome

Frequently asked questions

Is Domus 21 Luxury Suites pet-friendly?

Yes, this property allows cats and dogs (limit 4 total) with a maximum weight of up to 10 kg per pet.

What time is check-in at Domus 21 Luxury Suites?

Check-in start time: 2:00 PM; check-in end time: 11:30 AM.

What time is check-out at Domus 21 Luxury Suites?

Checkout is at 11:30 AM.

Does Domus 21 Luxury Suites provide a shuttle to the airport?

Yes, there's an airport shuttle that runs on request. A fee of EUR 70 per vehicle applies.

Where is Domus 21 Luxury Suites located?

This family-friendly Rome guesthouse is located near the airport, within a 5-minute walk of Corso Vittorio Emanuele II, Pantheon and Piazza Venezia. Piazza Navona and Via del Corso are also within 10 minutes. Venezia Tram Stop and Arenula-Cairoli Tram Station are within a 5-minute walk.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Domus 21 Luxury Suites Reviews

9.6

Exceptional

10

Cleanliness

9.4

Amenities

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 79 out of 94 reviews
Rating 8 - Good. 12 out of 94 reviews
Rating 6 - Okay. 2 out of 94 reviews
Rating 4 - Poor. 0 out of 94 reviews
Rating 2 - Terrible. 1 out of 94 reviews

Reviews

8/10 Good

Neil

Liked: Cleanliness, staff & service, amenities
Was shown the room and amenities. Great location
Stayed 1 night in Nov 2025

10/10 Excellent

Deanna

Liked: Cleanliness, amenities, property conditions & facilities
Very lovely property! Close to so many restaurants, shopping, bus stops and site seeing.
Stayed 4 nights in Jun 2025

10/10 Excellent

Heidi

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love this hotel!!! Awesome location, very nice inside, beds are super comfortable and staff was friendly and helpful! It also has a lift, which is great when u don’t pack light:-) They do not 24 reception so if you are arriving early or late you will just need to make arrangements.
Stayed 1 night in Oct 2025

10/10 Excellent

Sean

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Stay in Rome

Great location. Super clean. Friendly staff. Comfy bed. Hot shower. Everything I needed for my stay in Rome.
Stayed 1 night in Aug 2025

10/10 Excellent

diane

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a very unique and private property. The entrance was unsuspecting but easy to find. Once you went up the elevator and entered the guest services desk we were warmly welcomed. The room was very clean and the bed and linens very comfortable. We could not hear any street noise and had a pretty city view.
Stayed 3 nights in Sep 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice staff. Great location
Stayed 1 night in Apr 2025

10/10 Excellent

Yuri

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very good location and stylish
Stayed 2 nights in Nov 2024

10/10 Excellent

Nhu

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is exceptional space to spend time in Rome. The staff and rooms are superior. Their space is very aesthetic and the attention to detail in their design did not go unnoticed. I would not hesitate to stay here again! Thank you for the beautiful accommodations!
Stayed 1 night in Jun 2025

10/10 Excellent

Mikeala

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely size rooms that are really clean and quiet. Great location and friendly reception staff
Stayed 4 nights in Oct 2024

10/10 Excellent

Jose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent location and service. Even though the hotel doesn't have a 24 hr reception, the staff is invaluable with anything, and the size of the room and location are superb.
Stayed 5 nights in Apr 2025

8/10 Good

Dennis

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location, location, location. Great restaurants all around. Walkable to Trevi, the Colosseum and Pantheon.
Stayed 3 nights in Mar 2025

8/10 Good

Caitlyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property is in an excellent location. Walkable to many dining options and close to a lot of sight seeing. The suites are a little hard to find once you arrive and you have to go up the oldest and smallest elevator which was an Experience in itself! more directions prior Would have been helpful but overall it’s a great place for a quick trip in Rome!
Stayed 2 nights in Jun 2025

10/10 Excellent

Joshua

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Excellent hotel

One night stay in Rome before kicking off to the cruise ship. This was our first time in Rome. Amazing hotel! Had a great view, the ceiling is amazing, and the space was large and super clean. Super quiet had no problem sleeping at night, nor in the middle of the day nap as we were jet lagged getting here. The staff when we got here to check in, was so wonderful and inviting. This is definitely a place I am saving in my favorites to come back to again. Super great location, everything was very within walking distance. Newly married couple in our mid/upper 30s.
Stayed 1 night in Aug 2025

10/10 Excellent

Ira

Liked: Cleanliness, staff & service, property conditions & facilities
A five star experience in a well priced four star type property. Getting into place the first time is a bit of a challenge - street level passcode, up a flight of stairs to an old style elevator up to fifth floor - but once there, it's a lovely boutique property. Clean and front desk clerk very helpful.
Stayed 2 nights in May 2025

10/10 Excellent

zeline

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice rooms. good location. walkable to colusseum and many nice areas.
Stayed 3 nights in Mar 2024

8/10 Good

Alison

Liked: Cleanliness, staff & service, property conditions & facilities
Fabulous location. Very quiet and peaceful room.
Stayed 4 nights in Sep 2023

10/10 Excellent

Diana

Liked: Cleanliness, staff & service, property conditions & facilities
the staff was very attentive, nice, friendly, and welcoming, they also always made sure the room was always clean refilled my pear juice which was 10/10
Stayed 5 nights in Jul 2024

10/10 Excellent

Angela

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and spacious.
Stayed 2 nights in Jul 2024

10/10 Excellent

Anthony

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely apartments with an attentive staff. They graciously allowed an early check in on our arrival.

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great room, fantastic service

Only stayed one night but stay was fantastic. Front desk was very helpful in checking in, handling luggage early and planning transportation for us to the airport. Additional drinks/etc. that were already in the room were a bonus. Thanks for a great stay.
Stayed 1 night in Jul 2024

10/10 Excellent

Linda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was great, the location was awesome to walk to everything. There was a first foyer with security at the door so safety was wonderful. The room was spacious and the staff was very helpful with the luggage, assisted with tourist questions and walked me to my taxi to assure I was all set. Great stay and great staff. Such a great stay at a new property!
Stayed 2 nights in May 2024

10/10 Excellent

Brandon

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect

Our host was very hospitable, family-oriented, and kind. They accommodated us with very last minute reservations and our suite was extremely clean. Location was optimal also. We highly recommend this property! We were very pleased.
Stayed 1 night in Jul 2024

10/10 Excellent

David

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Amazing Hotel!!

This Hotel did not disappoint!! Exceptional! Staff, very friendly courteous and helpful! Great location and very easy to get to main attractions. We were there for eight days and we are so excited we will be returning there in a few days for another 3 nights! This little hotel was perfect!
Stayed 8 nights in Sep 2023

10/10 Excellent

Darcy

Really enjoyed our stay. Great location to walk to all the sights. Staff was lovely although not there all the time. Room was nice and great AC. An iron, water, coffee was provided daily. Our bathroom pocket door was difficult to close all the way, but otherwise I would have given it 5 stars.
Stayed 3 nights in Jun 2024

6/10 Okay

Peter

Liked: Cleanliness, staff & service
Disliked: Amenities, property conditions & facilities
There are better options for staying in the center of Rome. the location is good and the bed is comfy but otherwise there is no reason to stay here. We could hear our very loud neighbors early in the morning. The maintenance of the room was lacking, i.e. toilet seat, shower soap dish, lighting etc.
Stayed 2 nights in Feb 2025