Hotels in San Antonio

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
19 Nov - 20 Nov
Tomorrow
20 Nov - 21 Nov
This weekend
21 Nov - 23 Nov
Next weekend
28 Nov - 30 Nov

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in San Antonio

Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
6.1 km from San Antonio
8.4 out of 10, Very good, (2274)
"Spacious room, clean, good breakfast "
United States
Juan
The price is S$157
includes taxes & fees
26 Nov - 27 Nov
Crowne Plaza Panama Airport by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
15.8 km from San Antonio
9.0 out of 10, Wonderful, (1002)
"Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city."
United States
MICHELE
Central Hotel Panama Casco Viejo
Reception
Hotel Coral Suites

Hotel Coral Suites

3.5 star property
12.5 km from San Antonio
9.0 out of 10, Wonderful, (1002)
"Great place for the price. "
United States
Ryan
The price is S$97
includes taxes & fees
20 Nov - 21 Nov
Hotel Coral Suites
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

4.0 star property
16 km from San Antonio
9.6 out of 10, Exceptional, (192)
"The staff was very friendly and supportive. The room was spectacular! It was beautifully decorated and very clean. It was just a delight to stay in this lovely hotel!"
United States
Madelaine
La Concordia Boutique Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
13.1 km from San Antonio
9.0 out of 10, Wonderful, (1003)
"Very beautiful room was spotless, and staff was very good with customer service"
United States
Anthony
The price is S$245
includes taxes & fees
1 Dec - 2 Dec
Waldorf Astoria Panama
Outdoor spa tub
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 star property
12.7 km from San Antonio
9.2 out of 10, Wonderful, (1008)
"Staff was helpful, room was clean and I enjoyed my stay. "
United States
Lystra
The price is S$110
includes taxes & fees
2 Dec - 3 Dec
TRYP by Wyndham Panamá Centro
Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 star property
4.5 km from San Antonio
8.6 out of 10, Excellent, (1886)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is S$174
includes taxes & fees
20 Nov - 21 Nov
Riande Aeropuerto Hotel & Casino
Aerial view
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

3.5 star property
28.2 km from San Antonio
7.8 out of 10, Good, (654)
"We had a lovely stay, the views and tranquility of the place was my favorite part."
United States
Rebecca
The price is S$145
includes taxes & fees
23 Nov - 24 Nov
Gamboa Rainforest Reserve
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
11.9 km from San Antonio
9.2 out of 10, Wonderful, (1004)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is S$130
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City
Outdoor pool
Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina

3.0 star property
12.5 km from San Antonio
7.4 out of 10, Good, (264)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is S$85
includes taxes & fees
30 Nov - 1 Dec
Ramada Panama Centro Via Argentina
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

3.0 star property
12.2 km from San Antonio
9.0 out of 10, Wonderful, (1553)
"A nice hotel with plenty of shopping and restaurants in the area"
United States
Neil
The price is S$73
includes taxes & fees
23 Nov - 24 Nov
Principe Hotel and Suites
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
12.8 km from San Antonio
9.2 out of 10, Wonderful, (1005)
"great stay when in PTY"
United States
Fernando
The price is S$251
includes taxes & fees
25 Nov - 26 Nov
Bristol Panama, a Registry Collection Hotel
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento, 1.4 km from San Antonio
8.8 out of 10, Excellent, (1008)
"It was very clean good friendly staff good food i really love there goong back next time "
United States
Sylvester Keith
The price is S$157
includes taxes & fees
5 Dec - 6 Dec
Courtyard by Marriott Panama Metromall
Exterior
Aloft Panama

Aloft Panama

3.5 star property
10.3 km from San Antonio
8.6 out of 10, Excellent, (880)
"Great staff"
United States
RENE
The price is S$167
includes taxes & fees
26 Nov - 27 Nov
Aloft Panama
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 star property
12.3 km from San Antonio
7.6 out of 10, Good, (676)
"The breakfast was great, I love the pool."
United States
Estefani
The price is S$77
includes taxes & fees
20 Nov - 21 Nov
Hospedium Princess Hotel Panama
Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
4 km from San Antonio
9.6 out of 10, Exceptional, (629)
"Beautiful property. Excellent lunch, fish tacos were amazing. "
United States
Marc
The price is S$300
includes taxes & fees
23 Nov - 24 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Daily cooked-to-order breakfast (USD 15.00 per person)
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
11.5 km from San Antonio
8.8 out of 10, Excellent, (1000)
"Perfect stay "
United States
pedro
The price is S$175
includes taxes & fees
6 Dec - 7 Dec
Courtyard by Marriott Panama Multiplaza Mall
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
15.8 km from San Antonio
9.8 out of 10, Exceptional, (245)
"Many shops and restaurants nearby and the hotel is located in a beautiful area "
United States
Jerry
The price is S$523
includes taxes & fees
8 Dec - 9 Dec
Hotel La Compañía Casco Antiguo
Front of property
Hotel San Felipe

Hotel San Felipe

4.0 star property
15.9 km from San Antonio
9.4 out of 10, Exceptional, (229)
"Really nice staff and property is in amazing location "
United States
Michael
The price is S$174
includes taxes & fees
26 Nov - 27 Nov
Hotel San Felipe
Outdoor spa tub
Hilton Garden Inn Panama City Downtown, Panama

Hilton Garden Inn Panama City Downtown, Panama

3.5 star property
12.8 km from San Antonio
8.6 out of 10, Excellent, (1000)
"Excellent all around"
United States
Rolando
The price is S$116
includes taxes & fees
25 Nov - 26 Nov
Hilton Garden Inn Panama City Downtown, Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

Rufina Alfaro

Rufina Alfaro might not have many top sights, but Metromall Panama and Los Pueblos Commercial Center are two attractions nearby that you can check out.

José Domingo Espinar

José Domingo Espinar might not have many top sights, but Estadio Rommel Fernandez and Metromall Panama are two attractions nearby that you can check out.

Amelia Denis de Icaza

While there might not be top attractions in Amelia Denis de Icaza, you can explore the larger area and discover places like El Dorado Mall and Panama Viejo.

Victoriano Lorenzo

If you're looking for some top things to see and do in Victoriano Lorenzo and surrounding area, you can visit Panama Viejo and Estadio Rommel Fernandez.

Top San Antonio Hotel Reviews

Marriott Panama Hotel

Marriott Panama Hotel

10/10 Excellent
"Decent place to stay. Convenient and welcoming staff"
Allena 4-night trip
Posted 1 day ago
Marriott Panama Hotel

Explore a world of travel with Expedia

Frequently asked questions

What's it like in San Antonio?
San Antonio is a neighbourhood that travellers like for its shopping and gardens.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available in San Antonio.
What is there to do in this San Miguelito neighbourhood?
Metromall Panama, Los Pueblos Commercial Center and Estadio Rommel Fernandez are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Plaza de Francia and Atrio Mall are a couple of additional sights to visit in San Miguelito.