Hotels in San Antonio

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in San Antonio

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2042)
"The hotel was great , location was good "
Plaza Paitilla Inn Hotel

The Executive Hotel

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Great value and love the breakfast."
The Executive Hotel

Best Western Plus Panama Zen Hotel

4.0 star property
9.0 out of 10, Wonderful, (865)
"Everything about this hotel is outstanding !!!!"
The price is S$145
includes taxes & fees
23 Jun - 24 Jun
Best Western Plus Panama Zen Hotel

American Trade Hotel

4.5 star property
9.4 out of 10, Exceptional, (527)
"The staff are nice, informative, and friendly! "
The price is S$374
includes taxes & fees
8 Jul - 9 Jul
American Trade Hotel

Principe Hotel and Suites

3.0 star property
8.8 out of 10, Excellent, (1347)
"Great place to stay in Panama city"
The price is S$83
includes taxes & fees
11 Jun - 12 Jun
Principe Hotel and Suites

Nomada Container Hotel Panama City

3.0 star property
8.8 out of 10, Excellent, (137)
"I loved this place- great location, friendly staff, clean and comfy for a nice price. I've already booked my next stay!"
The price is S$102
includes taxes & fees
11 Jun - 12 Jun
Nomada Container Hotel Panama City

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1007)
"I enjoyed my stay. Everyone was very friendly and helpful."
The price is S$151
includes taxes & fees
21 Jun - 22 Jun
Courtyard by Marriott Panama Metromall

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1007)
"Hotel very clean and the staff was excellent "
The price is S$115
includes taxes & fees
11 Jun - 12 Jun
TRYP by Wyndham Panamá Centro

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
8.8 out of 10, Excellent, (958)
"Beautiful hotel "
The price is S$211
includes taxes & fees
23 Jun - 24 Jun
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Marriott Executive Apartments Panama City, Finisterre

4.0 star property
8.8 out of 10, Excellent, (605)
"We have stayed at the property twice and enjoyed our time there."
The price is S$143
includes taxes & fees
11 Jul - 12 Jul
Marriott Executive Apartments Panama City, Finisterre

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1000)
"It was quiet staff very helpful worth the stay"
The price is S$177
includes taxes & fees
28 Jun - 29 Jun
Courtyard by Marriott Panama Multiplaza Mall

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (878)
"Great place to stay"
The price is S$181
includes taxes & fees
21 Jun - 22 Jun
Sheraton Grand Panama

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Love the location and access to the Mall! "
The price is S$190
includes taxes & fees
13 Jun - 14 Jun
Marriott Panama Hotel

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1198)
"Great location. Nice breakfast. Would come back again."
The price is S$133
includes taxes & fees
11 Jun - 12 Jun
Decapolis Hotel Panama City

MARINN PLACE Financial District

3.5 star property
9.2 out of 10, Wonderful, (278)
"It was a overall great stay "
The price is S$137
includes taxes & fees
11 Jun - 12 Jun
MARINN PLACE Financial District

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
8.8 out of 10, Excellent, (1000)
"Excellent place to stay!"
The price is S$115
includes taxes & fees
13 Jun - 14 Jun
Holiday Inn Panama Distrito Financiero by IHG

Radisson Hotel Panama Canal

4.5 star property
8.4 out of 10, Very good, (1001)
"Is a great place, where you can relax and enjoy a great time."
The price is S$107
includes taxes & fees
17 Jun - 18 Jun
Radisson Hotel Panama Canal

Amarla Boutique Hotel Casco Viejo

3.0 star property
9.8 out of 10, Exceptional, (83)
"The staff was absolutely wonderful and accommodating. "
Amarla Boutique Hotel Casco Viejo

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1005)
"Very nice and clean hotel, "
The price is S$213
includes taxes & fees
22 Jun - 23 Jun
Las Americas Golden Tower Panama

Riande Urban Hotel

3.5 star property
8.8 out of 10, Excellent, (1005)
"Nice swimming pool, friendly stuff, good breakfast, "
The price is S$108
includes taxes & fees
11 Jun - 12 Jun
Riande Urban Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.
Cerro Viento map

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

Rufina Alfaro map

Rufina Alfaro

Rufina Alfaro might not have many top sights, but Metromall Panama and Los Pueblos Commercial Center are two attractions nearby that you can check out.

José Domingo Espinar map

José Domingo Espinar

José Domingo Espinar might not have many top sights, but Estadio Rommel Fernandez and Metromall Panama are two attractions nearby that you can check out.

Victoriano Lorenzo map

Victoriano Lorenzo

If you're looking for some top things to see and do in Victoriano Lorenzo and surrounding area, you can visit Panama Viejo and Estadio Rommel Fernandez.

Belisario Porras map

Belisario Porras

If you're looking for some top things to see and do in Belisario Porras and surrounding area, you can visit Estadio Rommel Fernandez and Metromall Panama.

Frequently asked questions

What's it like in San Antonio?

San Antonio is a neighbourhood that travellers like for its shopping and gardens.

If I need to cancel my hotel reservation in San Antonio, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available in San Antonio.

What is there to do in this San Miguelito neighbourhood?

Metromall Panama, Los Pueblos Commercial Center and Estadio Rommel Fernandez are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Plaza de Francia and Atrio Mall are a couple of additional sights to visit in San Miguelito.