San Antonio Holidays

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    Better together

    Save up to S$134 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
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Cerro Viento

1 out of top 10 points of interest in this area

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

Find hotels in Cerro Viento

Top hotels in San Antonio

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is S$168 per night from 21 Jul to 22 Jul
S$168
21 Jul - 22 Jul
includes taxes & fees
9/10 Wonderful! (4,097 reviews)
"The staff was very courteous"

Reviewed on 12 Jul, 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is S$314 per night from 1 Aug to 2 Aug
S$314
1 Aug - 2 Aug
includes taxes & fees
7.2/10 Good! (1,005 reviews)
"Un hotel muy acogedor!! Muy bonitas instalaciones"

Reviewed on 11 Jul, 2025

Dreams Playa Bonita Panama - All Inclusive
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is S$176 per night from 25 Jul to 26 Jul
S$176
25 Jul - 26 Jul
includes taxes & fees
8.4/10 Very Good! (892 reviews)
"a clean and nice hotel , Lobby area was very nice with some nice shopping places, the rooms need a little update especially the bathroom, the service was excellent friendly and courteous"

Reviewed on 8 Jul, 2025

Sheraton Grand Panama
See all 1,456 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio holiday package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in San Antonio from just . And the more you bundle, the more cash you save. The holiday of your dreams has never been more affordable.
How do I get a cheap travel package to San Antonio?
Our San Antonio holiday packages promise plenty of savings for the savvy traveller. For the best deal, simply combine your flights, hotels and extras (including tours) into one neat package. But great bargains are only the start of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotel options across the globe to pick from. Whatever your budget or style, there's a holiday package that's perfect for you.
Where should I stay in San Antonio?
If you're interested in visiting Metromall Panama, give commuting a miss and book a hotel nearby. It's one of the best attractions in this neighbourhood.
What are the top hotels in San Antonio?
Dumas Villas is one of San Antonio's most popular properties. Lock in a room here and you'll slumber peacefully knowing you're in capable hands.
How far in advance should I book my San Antonio holiday?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to 12 months in advance. If you can't see your preferred air carrier, or you've left things to the last minute, don't stress. Cheap fares to San Antonio sometimes occur within weeks of the date of departure.
What does an Expedia San Antonio travel package include?
From airfares and hotels to rental cars, Expedia can help you put together a San Antonio package that's right for you. Holidaying for a few weeks? Check out a rental car, flight and hotel bundle. If your break is short, a hotel and flight deal may be more your style. Experiences can also be added once you've made your booking. Our holiday packages make it a cinch to plan and save.
What should I know before booking a San Antonio travel package?
So many places to explore, so many things to do. With a package, you can check more of them off your list. Bundle your hotels, flights and rental cars and get set to save.
Can I choose my airline with a San Antonio Expedia holiday package?
Yes --- that's the beauty of an Expedia holiday package. You're in control. We have more than 550 airline partners all over the world, so you have lots of choice when putting together your San Antonio getaway.
If I'm not able to travel, can I cancel my San Antonio holiday package?
We totally get it --- unexpected stuff happens. If you've booked a San Antonio holiday package and need to cancel or amend it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you've booked your package within 24 hours, you may be able to cancel or amend your itinerary for free. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a fee.

Things to do

Panama city and canal tour's unforgettable.

Panama city and canal tour's unforgettable.

S$90
per adult
100% of travellers recommend
Panama city and canal tour's unforgettable.
Slingshot Tour Panama

Slingshot Tour Panama

S$149
per adult
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

S$191
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
See all activities in San Miguelito

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.