San Antonio Holidays

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    Save up to S$134 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
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José Domingo Espinar

José Domingo Espinar might not have many top sights, but Estadio Rommel Fernandez and Metromall Panama are two attractions nearby that you can check out.

Find hotels in José Domingo Espinar

Top hotels in San Antonio

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
The price is S$154 per night from 27 Apr to 28 Apr
S$154
27 Apr - 28 Apr
includes taxes & fees
Courtyard by Marriott Panama Metromall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is S$193 per night from 5 May to 6 May
S$193
5 May - 6 May
includes taxes & fees
9/10 Wonderful! (5,276 reviews)
We stayed for 7 nights. The hotel is in a safe neighborhood and within walking distance to so many restaurants - I think the farthest we had to walk was 7 minutes to a restaurant. We stayed in a king bed room and the room was very spacious - there was a small fridge and iron with ironing board and ...

Reviewed on 10 Apr, 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is S$186 per night from 4 May to 5 May
S$186
4 May - 5 May
includes taxes & fees
8.6/10 Excellent! (2,507 reviews)
Only there for one night but had everything we needed.

Reviewed on 10 Apr, 2026

Crowne Plaza Panama Airport by IHG
See all 1,388 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio holiday package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in San Antonio from just . And the more you bundle, the more cash you save. The holiday of your dreams has never been more affordable.
How do I get a cheap travel package to San Antonio?
Our San Antonio holiday packages promise plenty of savings for the savvy traveller. For the best deal, simply combine your flights, hotels and extras (including tours) into one neat package. But great bargains are only the start of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotel options across the globe to pick from. Whatever your budget or style, there's a holiday package that's perfect for you.
Where should I stay in San Antonio?
If you're interested in visiting Metromall Panama, give commuting a miss and book a hotel nearby. It's one of the best attractions in this neighbourhood.
What are the top hotels in San Antonio?
Dumas Villas is one of San Antonio's most popular properties. Lock in a room here and you'll slumber peacefully knowing you're in capable hands.
How far in advance should I book my San Antonio holiday?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to 12 months in advance. If you can't see your preferred air carrier, or you've left things to the last minute, don't stress. Cheap fares to San Antonio sometimes occur within weeks of the date of departure.
What does an Expedia San Antonio travel package include?
From airfares and hotels to rental cars, Expedia can help you put together a San Antonio package that's right for you. Holidaying for a few weeks? Check out a rental car, flight and hotel bundle. If your break is short, a hotel and flight deal may be more your style. Experiences can also be added once you've made your booking. Our holiday packages make it a cinch to plan and save.
What should I know before booking a San Antonio travel package?
So many places to explore, so many things to do. With a package, you can check more of them off your list. Bundle your hotels, flights and rental cars and get set to save.
Can I choose my airline with a San Antonio Expedia holiday package?
Yes — that's the beauty of an Expedia holiday package. You're in control. We have more than 550 airline partners all over the world, so you have lots of choice when putting together your San Antonio getaway.
If I'm not able to travel, can I cancel my San Antonio holiday package?
We totally get it — unexpected stuff happens. If you've booked a San Antonio holiday package and need to cancel or amend it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you've booked your package within 24 hours, you may be able to cancel or amend your itinerary for free. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a fee.

Popular places to visit

Templo Bahá'í

You can find out about the history of San Miguelito with a stop at Templo Bahá'í. Stroll along the seaside or visit the shops in this vibrant area.

Templo Bahá'í

Things to do

Panama Canal Half Transit Experience

Panama Canal Partial Transit

S$192
per adult
86% of travellers recommend
Panama Canal Partial Transit
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

S$63
per adult
98% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: POIN Swing Experience

Panama City: POIN Swing Experience

S$41
per adult
100% of travellers recommend
Panama City: POIN Swing Experience
See all activities in San Miguelito

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.