Hotels in Sanctuary

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Our top choices for Sanctuary hotels

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,305 reviews)
"Best place to stay!"
United States
Cory
The price is S$369
includes taxes & fees
24 Mar - 25 Mar
Lani Kai Beachfront Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,668 reviews)
"Super nice pool and bar area and easy to get to the beach. Clean rooms and great location. "
United States
Marjorie
The price is S$473
includes taxes & fees
12 Apr - 13 Apr
Sanibel Island Beach Resort

Villa Del Mar 402

Villa Del Mar 402
3.0 star property
24.9 km from Sanctuary
The price is S$1,122
includes taxes & fees
14 Mar - 15 Mar
Villa Del Mar 402

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 12.8 km from Sanctuary
8.6 out of 10, Excellent, (2,605 reviews)
"Great rooms, nice decor, very clean, clean property bathrooms, great views and pools. "
United States
William
The price is S$704
includes taxes & fees
12 Apr - 13 Apr
Sundial Beach Resort & Spa

Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 11.6 km from Sanctuary
8.8 out of 10, Excellent, (311 reviews)
"Clean rooms, great staff, beautiful view "
United States
Julia
The price is S$840
includes taxes & fees
10 Apr - 11 Apr
Casa Ybel Resort

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
20.4 km from Sanctuary
9.4 out of 10, Exceptional, (1,293 reviews)
"We loved our stay here! So much for the kids and adults to do!"
United States
Toni
The price is S$567
includes taxes & fees
12 Apr - 13 Apr
Pink Shell Beach Resort and Marina

Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
20.9 km from Sanctuary
9.4 out of 10, Exceptional, (1,002 reviews)
"The room overlooks the beach. Gorgeous views."
United States
Kim
The price is S$672
includes taxes & fees
4 Apr - 5 Apr
Best Western Plus Beach Resort

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 13.8 km from Sanctuary
9.2 out of 10, Wonderful, (1,001 reviews)
"Very clean and friendly staff. "
United States
Alexandria
The price is S$842
includes taxes & fees
3 Apr - 4 Apr
Sanibel Inn

Shalimar Beach Resort

Shalimar Beach Resort
2.0 star property
West End, 10.3 km from Sanctuary
10.0 out of 10, Exceptional, (34 reviews)
"Pool was great Clean room Excellent staff "
United States
Paul
The price is S$886
includes taxes & fees
25 Mar - 26 Mar
Shalimar Beach Resort

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
27.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,000 reviews)
"Beach view was absolutly outstanding. The staff was extremely friendly and helpful. The room was so big and beautiful and had everything you needed. Would be nive if they had a little breakfast area for sure. "
United States
luis perez
The price is S$967
includes taxes & fees
12 Apr - 13 Apr
Pointe Estero Beach Resort

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.4 out of 10, Exceptional, (1,002 reviews)
"This hotel is in a great location. Close to Fort Myers Beach and Sanibel Island. Lots of restaurant choices in the area. The hotel was clean and staff was friendly. The continental breakfast was a great benefit!"
United States
Sheila
The price is S$165
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very good, (1,005 reviews)
"Great view"
United States
Susan
The price is S$541
includes taxes & fees
1 Apr - 2 Apr
Marriott Sanibel Harbour Resort & Spa

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 12.8 km from Sanctuary
9.8 out of 10, Exceptional, (7 reviews)
"OUR NEW FAVORITE HOTEL! Cozy! Clean! All New! So Quaint! Filled with local charm!!! Every amenity you could need!!!"
United States
Molly
The price is S$401
includes taxes & fees
22 Mar - 23 Mar
The Anchor Inn

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (970 reviews)
"We enjoyed bike riding, the pool, and the many outdoor amenities that were available. The restaurant next door was great too! Staff was very friendly and helpful!"
United States
Cindy
Latitude 26 Waterfront Resort & Marina

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
3.7 km from Sanctuary
8.6 out of 10, Excellent, (1,000 reviews)
"Lovely location, pools and restaurants."
United States
Linda
The price is S$583
includes taxes & fees
12 Apr - 13 Apr
Tween Waters Island Resort & Spa

Edison Beach House

Edison Beach House
3.5 star property
21.2 km from Sanctuary
9.4 out of 10, Exceptional, (1,676 reviews)
"Great hotel in close proximity to bars and restaurants. The hotel is steps from the public beach and the ocean view is awesome!"
United States
Jason
Edison Beach House

Angler's Inn

Angler's Inn
2.5 star property
18.8 km from Sanctuary
9.4 out of 10, Exceptional, (327 reviews)
"Great place. Walking distance from a little parade of local craft stores and restaurants. Right on a secluded canal teeming with fish and bird life. Clean and perfect for what we needed. "
United States
Mark
The price is S$363
includes taxes & fees
18 Mar - 19 Mar
Angler's Inn

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (837 reviews)
"Just stayed one night. Room was clean, staff was helpful and polite. Did not swim but the pool looked great. Continental breakfast was actually good. "
United States
Angela
The price is S$132
includes taxes & fees
5 Apr - 6 Apr
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
22.9 km from Sanctuary
8.6 out of 10, Excellent, (1,001 reviews)
"Great location, next to dining, Walmart and the trolley. "
United States
John
The price is S$152
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
22.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,086 reviews)
"Everything about this place was fabulous!"
United States
Elizabeth Ann
DiamondHead Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 10 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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