Santa Cruz Hotels from

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Santa Cruz hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (342)
"Accommodating staff, comfortable rooms, wonderful pool"
Canada
Jay
The price is S$171
15 Dec - 16 Dec
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ibis Santa Cruz DE LA Sierra

3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (69)
"Great Spot"
United States
Jose
The price is S$46
8 Dec - 9 Dec
Ibis Santa Cruz DE LA Sierra

Sun Hotel

3.5 star property
Santa Cruz
8.4 out of 10, Very good, (327)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is S$117
29 Nov - 30 Nov
Sun Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is S$84
29 Nov - 30 Nov
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hotel Cortez

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (120)
"The staff and property are second to none! "
United States
Cynthia
The price is S$165
26 Nov - 27 Nov
Hotel Cortez

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (206)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is S$145
29 Nov - 30 Nov
Marriott Santa Cruz de la Sierra Hotel

Delfines Collection Hotel By Mercure

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (71)
"Clean comfortable rooms "
United States
mary
The price is S$61
29 Nov - 30 Nov
Delfines Collection Hotel By Mercure

Camino Real Hotel

4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (406)
"The parrots. Unique"
United States
Juan P
The price is S$165
10 Dec - 11 Dec
Camino Real Hotel

HOTEL OSHO

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (28)
"Staff is great and place is comfortable "
United States
DITMAR
The price is S$77
21 Dec - 22 Dec
HOTEL OSHO

Apart Hotel Premium Suites Santa Cruz

3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz

Lido Hotel

3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (29)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is S$60
26 Nov - 27 Nov
Lido Hotel

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is S$137
7 Dec - 8 Dec
Novotel Santa Cruz De La Sierra

Hotel Las Américas

3.0 star property
Santa Cruz
6.0 out of 10, (1)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is S$50
26 Nov - 27 Nov
Hotel Las Américas

TRYP by Wyndham Santa Cruz

4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (142)
"Nice stay with good service "
United States
Jianyuan
The price is S$91
1 Dec - 2 Dec
TRYP by Wyndham Santa Cruz

Hotel LP Santa Cruz Centro

3.0 star property
Santa Cruz
8.0 out of 10, Very good, (280)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro

Chairú Eco Hotel

3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (44)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (78)
"Good price, great hotel!"
United States
James
The price is S$51
24 Nov - 25 Nov
Premium Suites Deluxe Aparthotel Equipetrol

Hotel G

3.5 star property
Santa Cruz
7.8 out of 10, Good, (104)
"Excelente Hotel "
Mexico
JACOB
Hotel G

Hotel LP Equipetrol

3.5 star property
Santa Cruz
8.2 out of 10, Very good, (201)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol

Swissôtel Santa Cruz De La Sierra

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (79)
"Beautiful hotel"
Australia
Joanna
The price is S$135
6 Dec - 7 Dec
Swissôtel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Black Friday Sale

Save up to 50% on select hotels
Showing deals for:5 Dec - 7 Dec
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

San Lorenzo Cathedral showing a park

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Top reasons to visit Santa Cruz

  • Vibrant Culture: Santa Cruz boasts rich cultural experiences with its piazzas, cathedrals, and local landmarks.
  • Outdoor Adventures: The stunning Santa Cruz mountains and picturesque beaches offer ample opportunities for relaxation and adventure.
  • Family-Friendly Activities: The city is ideal for family vacations, with various attractions and outdoor spaces to explore.
  • Diverse Accommodation: From luxurious hotels to budget hostels, there's something for every type of traveller.
  • Leisure and Shopping: Enjoy shopping centres, leisure activities, and a vibrant music scene in the heart of the city.

Find great hotels in Santa Cruz

Discover a diverse array of accommodation options in Santa Cruz, Bolivia, catering to every traveller's needs. Whether you're seeking a family-friendly hotel, a pet-friendly haven, or a business-focused stay, the city offers it all. From vibrant hostels to luxurious beachfront hotels, including the renowned Dream Inn, you'll find the perfect base for your Bolivian adventure. Experience the best hotels that combine comfort and convenience in this charming destination.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Nestled in the heart of Santa Cruz, Los Tajibos offers a sophisticated blend of luxury and comfort, making it ideal for business and leisure travellers alike. The hotel features a full-service spa and an inviting outdoor pool, perfect for relaxation after a busy day. Business amenities, including a well-equipped conference centre and accessible business facilities, cater to corporate guests. Experience a serene city-themed getaway, complete with body wraps and a hot tub, ensuring a revitalising stay in this vibrant urban setting.
  • Hotel G: Hotel G embraces a unique pet-friendly ethos, welcoming furry companions to share in your travel adventures. This stylish 3.5-star hotel is perfect for those who wish to bring their pets along, offering amenities tailored to ensure both you and your pets feel at home. With a relaxed atmosphere and a convenient location in Santa Cruz, guests can enjoy a comfortable stay with their pets by their side. The hotel prides itself on its accommodating pet policy, making it an excellent choice for animal lovers seeking a memorable holiday experience.
  • Marriott Santa Cruz de la Sierra Hotel: As a luxurious 5-star accommodation, the Marriott Santa Cruz de la Sierra Hotel is perfect for families and those seeking an indulgent escape. The hotel boasts an impressive full-service spa, providing a range of treatments to rejuvenate your senses, alongside a refreshing pool area with umbrellas for relaxation. Families will appreciate the complimentary cribs for younger guests, ensuring a comfortable stay for all. Situated in a prime location, this hotel offers both elegance and convenience for a truly remarkable Bolivian holiday experience.

Where to stay in and around Santa Cruz

Santa Cruz, Bolivia, offers a delightful blend of urban charm and outdoor adventure. Whether you're strolling through the vibrant downtown or exploring the scenic Santa Cruz mountains, there's something for everyone. Enjoy the friendly atmosphere and take advantage of beach access for relaxation. Don't miss out on the city's favourite spots, where you can immerse yourself in local culture and create unforgettable memories during your family-friendly vacation.

  • Warnes: Located 30.6km from the vibrant heart of Santa Cruz, Warnes is a charming city that offers a blend of urban convenience and family-friendly experiences. Although visitor numbers are relatively steady throughout the year, peaks occur in September and during the festive months of December to January. Travellers are drawn to Warnes for its shopping centres and resorts, making it an excellent destination for those looking to indulge in retail therapy or relax in leisure facilities. Local attractions, such as the botanical garden and various places of worship, add a cultural dimension to your visit, ensuring a well-rounded travel experience.
  • Colinas del Urubo: Nestled within the Santa Cruz area, Colinas del Urubo is a tranquil village perfect for outdoor enthusiasts and families alike. With visitor numbers peaking in March and from September to October, this village provides a serene escape from the bustling city. Featuring picturesque resorts and a stunning botanical garden, Colinas del Urubo offers ample opportunities for relaxation and exploration amidst nature. Whether you are seeking adventure or family bonding time, this village promises memorable experiences in a serene setting.
  • La Guardia: Just 20.9km from Santa Cruz, La Guardia is an adventurous city that caters to outdoor lovers and families. Peak visitor numbers in September and the festive season of December to January signal its popularity among those seeking adventure. The city offers a variety of activities, including access to resorts and nearby attractions such as a picturesque waterfall and a lovely piazza square. With its rich natural beauty and welcoming atmosphere, La Guardia is an ideal destination for those looking to create lasting memories with loved ones.

Things to do in Santa Cruz

Santa Cruz, Bolivia, is an ideal destination for city-themed and family outdoor vacations, offering a vibrant music scene and various activities. Visitors can explore the city through its shopping centres and malls, enjoy leisure time at the Pasatiempo Golf Club, and relax at the beach boardwalk. Whether indulging in retail therapy or discovering local culture, Santa Cruz promises a delightful experience for all travellers.

Shopping

For a vibrant shopping experience in Santa Cruz, visit Ventura Mall for entertainment and family vibes. La Recova Artisan Walk offers local crafts, while Patio Design LifeStyle Center combines shopping with a lively atmosphere. If you're up for a drive, explore more unique options beyond the city centre.

Recreation

Experience the vibrant atmosphere at Ramon Tahuichi Aguilera Stadium, where you can engage in various sports activities and soak up the local culture. The stadium offers a unique environment to enjoy fitness and recreation amidst the lively spirit of Santa Cruz.

Adventure

In Santa Cruz, explore the incredible Amboró National Park, where you can hike through diverse ecosystems and spot exotic wildlife. For adrenaline seekers, head to the nearby Lomas de Arena, offering thrilling sandboarding experiences amidst stunning dunes.

Nightlife

The nightlife in Santa Cruz offers a vibrant mix of entertainment. Catch a film at Cine Center for a romantic evening, or immerse yourself in culture at the Casa Municipal de Cultura Raúl Otero Reiche, where family-friendly performances light up the night.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money during your visit to Santa Cruz, consider travelling in June, August, or November when prices are lower. Saturdays offer the best hotel rates, while Tuesdays are the most expensive. Utilise Expedia’s search tool to filter by budget and eco-friendly options, and consider booking a package that combines your hotel, flights, and activities for additional savings. Additionally, explore free activities in the city to enhance your experience without straining your finances.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are June, August and November, where the prices are slightly lower. This is in comparison to March to April and September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Make use of Expedia’s search tool to refine your choices based on your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are currently available. To find the best prices and offers, simply adjust the price filter to sort from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Santa Cruz with your flights and activities through an Expedia package.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is an excellent destination for city-themed, family, and outdoor vacations. Visitors can explore notable attractions such as piazzas, cathedrals, and landmarks that offer rich cultural experiences. For those seeking leisure, the scenic Santa Cruz mountains, picturesque beaches, and the Santa Cruz wharf provide plenty of opportunities for relaxation and adventure, making it a perfect getaway for families and outdoor enthusiasts alike.

  • Plaza 24 de Septiembre: This vibrant square serves as the heart of Santa Cruz, bustling with life and culture. Surrounded by cafes and shops, it’s a perfect spot for mingling with locals and enjoying street performances in a lively atmosphere.
  • San Lorenzo Cathedral: A stunning example of colonial architecture, San Lorenzo Cathedral boasts intricate details and a serene ambience. Visitors can admire its beautiful stained glass windows while soaking in the cultural heritage of the region.
  • Blacutt Square: This landmark is ideal for excursions, offering a peaceful retreat from the city’s hustle. Surrounded by lush greenery, it’s a great place to relax and enjoy the natural beauty of Santa Cruz.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are slightly low and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly HighAverage
February77.0°F (25.0°C)Light RainMostly CloudyAverageAverage
March76.5°F (24.7°C)Light RainMostly SunnyAverageSlightly High
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnySlightly HighAverage
August72.9°F (22.7°C)No RainSunnyAverageSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnySlightly LowAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageSlightly Low
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowAverage

The nearest major airports for your trip to Santa Cruz

Flying into Santa Cruz, Bolivia, you will arrive at Viru Viru International Airport (VVI), situated 16.1km from the city centre. Excellent hotel options nearby include the 5-star Marriott Santa Cruz de la Sierra and Radisson Hotel Santa Cruz, both located 14.5km from VVI. For a slightly further option, Buganvillas Hotel Suites & Spa, a 4-star hotel, is 17.7km away. These hotels provide convenient transportation services to the airport, including 24-hour airport shuttles and various transfer options, ensuring a smooth journey to and from your accommodation.

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Chairú Eco Hotel is a favourite with Expedia customers. This hotel offers 2 restaurants and a bar. Reviews from our site also recommend Alfonsina Hotel Boutique by Inboccaluppo and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 274 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Ethno-folkloric Museum, Cine Center and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Lomas de Arena Regional Park and Arenal Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.

Explore a world of travel with Expedia