A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Check availability on Santa Cruz Luxury Hotels

Tonight
20 Aug - 21 Aug
Tomorrow
21 Aug - 22 Aug
This weekend
21 Aug - 23 Aug
Next weekend
28 Aug - 30 Aug

Our top choices for Santa Cruz luxury hotels

Massages
Lunch and dinner served
Meeting facility
Exterior

1. Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
Santa Cruz
  • Indulge in spa treatments, outdoor pool relaxation, and friendly concierge service at this entertainment district luxury retreat.
S$208
5 Sept - 6 Sept
Swissôtel Santa Cruz De La Sierra
Reception
Indoor spa tub
Reception
Breakfast, lunch and dinner served

2. Camino Real Hotel

Camino Real Hotel
Santa Cruz
  • Waterside luxury retreat with full-service spa offers poolside cocktails, garden-view dining, and indoor-outdoor swimming pools.
S$184
14 Sept - 15 Sept
Camino Real Hotel
Outdoor pool, pool umbrellas, pool loungers
Banquet hall
Lobby lounge
Breakfast, lunch and dinner served

3. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
Santa Cruz
  • Luxury escape in Santa Cruz's business district offers full-service spa treatments, outdoor pool relaxation, and upscale dining.
S$134
28 Aug - 29 Aug
Marriott Santa Cruz de la Sierra Hotel
Lobby sitting area
Free daily buffet breakfast
Restaurant
Lobby lounge

4. Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
Santa Cruz
  • Indulge in art deco elegance at this Santa Cruz hotel with luxurious pools and concierge service.
S$164
1 Sept - 2 Sept
Novotel Santa Cruz De La Sierra
Exterior detail
Down duvets, minibar, in-room safe, blackout curtains
Reception
Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas

5. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
Santa Cruz
S$125
22 Aug - 23 Aug
TRYP by Wyndham Santa Cruz
Lounge
Garden
Breakfast, lunch and dinner served
In-room safe, blackout curtains, iron/ironing board

6. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Santa Cruz
  • Indulge in luxury and convenience at this 4.5-star Bolivia hotel offering fine dining, fitness amenities, and garden views.
S$94
27 Aug - 28 Aug
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
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Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."
Andrew 4-night trip
Posted 4 days ago
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Frequently asked questions

Are you looking for a luxury hotel for your Santa Cruz holiday?
Travel to Santa Cruz (SRZ-El Trompillo) Airport or Santa Cruz (VVI-Viru Viru Intl.) Airport, and then treat yourself to a stay at one of 6 Santa Cruz luxury hotels. Santa Cruz has some interesting things to see and do including Plaza 24 de Septiembre and Ramon Tahuichi Aguilera Stadium, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are two other upscale options for your trip.
How many luxury hotels are there in Santa Cruz?
Lie in the lap of luxury during your getaway to Santa Cruz in one of Expedia's 6 luxury hotels.
When can I expect good weather in Santa Cruz?
Planning for the weather is a good way to make your trip to Santa Cruz relaxing and enjoyable, especially when you're splurging. The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.
What's there to see and do in Santa Cruz?
Enjoy all that Santa Cruz has to offer when you visit Plaza 24 de Septiembre, Ramon Tahuichi Aguilera Stadium and Cine Center. If you have a little extra time during your trip, you might want to make a stop at Santa Cruz Zoo and Ventura Mall.
How can I get around Santa Cruz?
It's easier to get around town comfortably when you know your options. To venture out into the surrounding area, hop aboard a train at Santa Cruz de la Sierra Station.