Santa Cruz Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to S$1,300 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
A tree-lined street with parked motorcycles and cars, and a person walking.

Historical Center

7 out of top 10 points of interest in this area
4.5/5(631 area reviews)

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Find hotels in Historical Center

Top hotels in Santa Cruz

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
The price is S$609 per night from 2 Aug to 3 Aug
S$609
2 Aug - 3 Aug
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
"An amazing hotel which i would definitely recommend. The room was beautiful but the air-con was not the best. Amazing staff who couldn't do enough for you."

Reviewed on 9 Jul, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
The price is S$185 per night from 1 Aug to 2 Aug
S$185
1 Aug - 2 Aug
includes taxes & fees
9.2/10 Wonderful! (1,010 reviews)
"Such a magical place in Sevilla! We had a lovely time staying here, from the moment I walked I through the doors Las Casas de la Judería just immerses you into the Spanish magic. The facility is well kept, there are some cool amenities (pool on the terrace, spa, breakfast, piano bar). It’s such a ..."

Reviewed on 9 Jul, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
The price is S$72 per night from 27 Jul to 28 Jul
S$72
27 Jul - 28 Jul
includes taxes & fees
8.8/10 Excellent! (1,015 reviews)
"This is an absolute gem of a hotel that should be rated more than just 2 stars. Excellent central location - so easy to get to by bus from the airport, no more than 10 minute walk to most of the historical sites. There are restaurants galore on the doorstep, including one literally steps opposite ..."

Reviewed on 9 Jul, 2026

Hotel Murillo
See all 413 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting . When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz holiday package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1,000,000 properties around the world. Whether you're enjoying a break with the whole family or travelling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz holiday?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our holiday packages today.
Can I choose my airline with a Santa Cruz Expedia holiday package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organising your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
Once a Moorish fort, this architectural gem is now the oldest functioning palace in Europe.
See properties

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.