Top 10 Serra Highlands Hotels of 2026

The Golden Gate Bridge spanning the Golden Gate Strait, with a city skyline in the background.

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Our top choices for Serra Highlands hotels

1. Best Western Plus Grosvenor Airport Hotel

4.3 km from Serra Highlands

EDDIE

includes taxes & fees

30 Aug - 31 Aug

2. DoubleTree by Hilton San Francisco South Airport Blvd

4.1 km from Serra Highlands

Ashley

includes taxes & fees

6 Sept - 7 Sept

3. Home2 Suites by Hilton San Francisco Airport North

The East Side, 4.4 km from Serra Highlands

Lizset

includes taxes & fees

23 Aug - 24 Aug

4. Embassy Suites by Hilton San Francisco Airport Oyster Point

The East Side, 4.3 km from Serra Highlands

Alain

includes taxes & fees

6 Sept - 7 Sept

5. La Quinta Inn & Suites by Wyndham San Francisco Airport N

Downtown South San Francisco, 3.8 km from Serra Highlands

Denis

includes taxes & fees

23 Aug - 24 Aug

6. Hotel Aluxor SFO

5 km from Serra Highlands

Christina

includes taxes & fees

23 Aug - 24 Aug

Desk, blackout curtains, iron/ironing board, free WiFi

7. Hotel Nova SFO

4.4 km from Serra Highlands

Aarzu

includes taxes & fees

15 Aug - 16 Aug

In-room safe, desk, laptop workspace, iron/ironing board

8. Hotel Skye SFO

5.1 km from Serra Highlands

Jaspreet

includes taxes & fees

23 Aug - 24 Aug

Hypo-allergenic bedding, pillow-top beds, laptop workspace

9. The Atrium Hotel

4.7 km from Serra Highlands

SOHAIL

includes taxes & fees

23 Aug - 24 Aug

10. Sonesta Select San Francisco Airport Oyster Point Waterfront

Oyster Point, 5 km from Serra Highlands

Renato

includes taxes & fees

23 Aug - 24 Aug

11. Comfort Inn and Suites San Francisco Airport North

The East Side, 4 km from Serra Highlands

Arcangel

includes taxes & fees

6 Sept - 7 Sept

Premium bedding, pillow-top beds, in-room safe, desk

12. Villa Montes Hotel

4.7 km from Serra Highlands

Anna

includes taxes & fees

5 Sept - 6 Sept

Desk, laptop workspace, blackout curtains

13. Gateway Inn & Suites San Francisco SFO Airport

4.9 km from Serra Highlands

david

includes taxes & fees

23 Aug - 24 Aug

14. Hotel Aura SFO

5.7 km from Serra Highlands

Andres

includes taxes & fees

16 Aug - 17 Aug

15. DoubleTree by Hilton San Francisco Airport North Bayfront

5.7 km from Serra Highlands

Robert

includes taxes & fees

6 Sept - 7 Sept

16. La Quinta Inn & Suites by Wyndham San Francisco Airport West

6.7 km from Serra Highlands

Colleen

includes taxes & fees

7 Sept - 8 Sept

17. Aloft by Marriott San Francisco Airport

8.7 km from Serra Highlands

Jeffrey

includes taxes & fees

30 Aug - 31 Aug

18. Hotel 1550 - SFO Airport

6.5 km from Serra Highlands

Victoria

includes taxes & fees

16 Aug - 17 Aug

19. Hyatt Regency San Francisco Airport

10.2 km from Serra Highlands

Juliana

includes taxes & fees

6 Sept - 7 Sept

20. The Millwood - A Boutique Hotel

6.8 km from Serra Highlands

Susan

includes taxes & fees

7 Sept - 8 Sept

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Where to stay in Serra Highlands

Find the best Serra Highlands areas for the activities you enjoy most.

A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Dating back to the middle of the 19th Century, this historic wharf has been through many incarnations. Today it’s bursting with fun, sea lions and restaurants.

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A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Fashion puts its best foot forward in this vast shopping plaza.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

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Top Serra Highlands Hotel Reviews

DoubleTree by Hilton Hotel Berkeley Marina

10/10 Excellent

"Loved our stay! Comfortable bed with a spacious room."

Handlery Union Square Hotel

8/10 Good

"You can't beat the location of this hotel, it was very central and easy to take public transport around it. The pool is a nice added bonus, it was warmed though unfortunately SF was too cold for us to truly enjoy the pool, though there was plenty of other people who seemed to be enjoying it. The staff was very professional and helpful. The lobby was very nice as well. Now the hotel itself is definitely run down. Our room was over in the "premium" section which was not at all premium. Perhaps in the main building the rooms are nicer but our area it was definitely run down and in great need of some basic upgrading. This extended into our rooms as well. The beds were not that comfortable, the bathroom had some traces of leftover hair and the water in the shower would stop for 1 second, not enough to make it uncomfortable but definitely strange. Hair is tricky and I'm sure they cleaned so it didn't bother me but its just an extra level of detail they are not checking. I never mentioned this to the staff as in the end I was able to live with it but I'm certain they would have made it right if I had asked. Though I'd definitely look around for options first I wouldn't exclude this hotel from future stays. It is definitely good enough and definitely the location and pool are really great to have so I would stay again if the price was right."

Chancellor Hotel on Union Square

10/10 Excellent

"This is a hidden gem! We were somewhat leery booking this property because the price was $150 for the night. What we experienced was a great boutique style hotel. The room was smaller but had a large walk in closet, which you don’t see in hotels. This allowed us to put luggage in there and made the room feel bigger. Highly recommend staying here!"

Frequently asked questions

What is Serra Highlands like?

Travellers to South San Francisco's Serra Highlands neighbourhood will be sure to enjoy a stay here.

How many hotels will I find in the Serra Highlands area?

Book one of Expedia's 5 hotels and other accommodation options in Serra Highlands and start exploring everything South San Francisco has to offer.

If I need to cancel my hotel reservation in Serra Highlands, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the best deals in Serra Highlands.

What is there to do in this South San Francisco neighbourhood?

Cypress Lawn Memorial Park, Hills of Eternity Memorial Park and Wyatt Earp's Grave are just a few of the places to visit in and around Serra Highlands. While you're out sightseeing, Pet's Rest Cemetery and Serramonte Center are a couple of additional sights to visit in South San Francisco.

Hotels in Serra Highlands

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Our top choices for Serra Highlands hotels

1. Best Western Plus Grosvenor Airport Hotel

2. DoubleTree by Hilton San Francisco South Airport Blvd

3. Home2 Suites by Hilton San Francisco Airport North

4. Embassy Suites by Hilton San Francisco Airport Oyster Point

5. La Quinta Inn & Suites by Wyndham San Francisco Airport N

6. Hotel Aluxor SFO

7. Hotel Nova SFO

8. Hotel Skye SFO

9. The Atrium Hotel

10. Sonesta Select San Francisco Airport Oyster Point Waterfront

11. Comfort Inn and Suites San Francisco Airport North

12. Villa Montes Hotel

13. Gateway Inn & Suites San Francisco SFO Airport

14. Hotel Aura SFO

15. DoubleTree by Hilton San Francisco Airport North Bayfront

16. La Quinta Inn & Suites by Wyndham San Francisco Airport West

17. Aloft by Marriott San Francisco Airport

18. Hotel 1550 - SFO Airport

19. Hyatt Regency San Francisco Airport

20. The Millwood - A Boutique Hotel

Where to stay in Serra Highlands

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Serra Highlands Hotel Reviews

DoubleTree by Hilton Hotel Berkeley Marina

Frequently asked questions

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