Name: Hotel Murillo
Price range: S$140

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)

Once a Moorish fort, this architectural gem is now the oldest functioning palace in Europe.

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Things to do

From Seville: Ronda and Setenil de las Bodegas Day Trip

From Seville: Discover SETENIL & RONDA

S$72

per adult

90% of travellers recommend

Seville: Setas de Sevilla Entry Ticket

S$23

per adult

80% of travellers recommend

Seville: Guadalquivir River Cruise

S$26

per adult

80% of travellers recommend

Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla

S$161

per adult

90% of travellers recommend

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

S$52

per adult

88% of travellers recommend

Alcazar and Cathedral & Giralda of Seville. Skip The Line! Includes access tickets

S$102

per adult

86% of travellers recommend

See all activities in Seville

Top hotels in Santa Cruz

Las Casas de la Judería, Sevilla Historic City Center

Calle Santa Maria La Blanca 5 Seville Seville

S$212

25 Nov - 26 Nov

includes taxes & fees

Stay at this spa hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...

9.2/10 Wonderful! (1,021 reviews)

"Hot water for taking a bath was good. Swimming pool was cold."

Reviewed on 24 Oct, 2026

Hotel Amadeus Sevilla

Calle Farnesio 6 Seville Seville

Fully refundableReserve now, pay when you stay

S$195

22 Nov - 23 Nov

includes taxes & fees

Stay at this boutique hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the breakfast and the bar in their reviews. ...

9.6/10 Exceptional! (1,294 reviews)

"A charming lovely gem of a hotel in the historic part of Seville. Family owned and operated just a lovely place to stay. The breakfast every morning was incredible."

Reviewed on 26 Oct, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2 Seville Seville

S$836

23 Nov - 24 Nov

includes taxes & fees

Stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge) and 24-hour room service. Our guests praise the helpful staff in their reviews. ...

Hotel Fernando III

San Jose 21 Seville Seville

S$181

26 Nov - 27 Nov

includes taxes & fees

Stay at this business-friendly hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their ...

9.6/10 Exceptional! (1,393 reviews)

"The hotel location is only minutes from the Giralda and the Alcazar , the breakfast have a lot of options and was very tasty. This is one of my favorites hotel if your are planing to visit Sevilla this is the one."

Reviewed on 26 Oct, 2026

Hotel Rey Alfonso X

Calle Ximenez De Enciso, 35 Seville Seville

S$209

23 Nov - 24 Nov

includes taxes & fees

Stay at this hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...

9.4/10 Exceptional! (1,226 reviews)

"Very nice hotel in a great location"

Reviewed on 26 Oct, 2026

Hotel Murillo

Calle Lope de Rueda, 7-9 Seville Seville

S$140

8 Nov - 9 Nov

includes taxes & fees

Stay at this family-friendly hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

See all 411 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

A bustling urban street lined with historic buildings and trees.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

A river with boats, a historic tower, and a cityscape with trees and buildings.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

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A modern architectural structure with a unique, wave-like design.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

A large, illuminated bridge with circular arches over a calm river.

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

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