South Main Hotels from from S$73

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Our top choices for South Main hotels

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1,222 reviews)
"Front desk staff was very professional and kind."
United States
MARINA
The price is S$148
includes taxes & fees
23 Mar - 24 Mar
Wyndham Houston near NRG Park/Medical Center

Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG
2.5 star property
South Main
7.4 out of 10, Good, (837 reviews)
"This is a safe, friendly hotel close to MDA Cancer Center"
United States
Myra
The price is S$171
includes taxes & fees
23 Mar - 24 Mar
Candlewood Suites Houston Medical Center by IHG

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (1,001 reviews)
"Easy access to stadium "
United States
Richard
The price is S$104
includes taxes & fees
23 Mar - 24 Mar
Wingate Houston near NRG Park/Medical Center

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1,008 reviews)
"Clean room, helpful staff and good location to hospital."
United States
George
The price is S$180
includes taxes & fees
22 Feb - 23 Feb
Comfort Suites Houston near Medical Center- NRG Stadium

Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center
2.5 star property
South Main
6.6 out of 10, (1,002 reviews)
"Courteous staff, clean room, quite property"
United States
Javier
The price is S$112
includes taxes & fees
23 Mar - 24 Mar
Quality Inn & Suites NRG Park - Medical Center

Best Western Plus Pearland/Houston Medical Center Hotel

Best Western Plus Pearland/Houston Medical Center Hotel
2.5 star property
Southeast Houston
9.4 out of 10, Exceptional, (137 reviews)
"Room was clean, and the staff friendly "
United States
Angie
The price is S$132
includes taxes & fees
23 Feb - 24 Feb
Best Western Plus Pearland/Houston Medical Center Hotel

Palace Inn Blue Edgebrook

Palace Inn Blue Edgebrook
3.0 star property
Southeast Houston
9.4 out of 10, Exceptional, (154 reviews)
"Such a great place to stay! Absolutely amazing!"
United States
Charlette
The price is S$135
includes taxes & fees
23 Feb - 24 Feb
Palace Inn Blue Edgebrook

Courtyard by Marriott Houston Intercontinental Airport

Courtyard by Marriott Houston Intercontinental Airport
3.0 star property
Houston
9.0 out of 10, Wonderful, (1,171 reviews)
"This is the second time we’ve stayed here to fly out of IAH. "
United States
Kadie
The price is S$186
includes taxes & fees
16 Mar - 17 Mar
Courtyard by Marriott Houston Intercontinental Airport

Tru by Hilton Houston Webster NASA

Tru by Hilton Houston Webster NASA
2.5 star property
Webster
9.0 out of 10, Wonderful, (1,005 reviews)
"Was a good hotel "
United States
Kathy
The price is S$116
includes taxes & fees
15 Mar - 16 Mar
Tru by Hilton Houston Webster NASA

Holiday Inn Express Hotel & Suites - Houston Space Center by IHG

Holiday Inn Express Hotel & Suites - Houston Space Center by IHG
2.5 star property
Webster
9.0 out of 10, Wonderful, (1,003 reviews)
"Great staff and very clean hotel. "
United States
Matthew
The price is S$117
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express Hotel & Suites - Houston Space Center by IHG

Hampton Inn & Suites Houston-Bush Intercontinental Aprt

Hampton Inn & Suites Houston-Bush Intercontinental Aprt
3.0 star property
Houston
8.8 out of 10, Excellent, (1,789 reviews)
"Great place "
United States
Susan
The price is S$143
includes taxes & fees
23 Mar - 24 Mar
Hampton Inn & Suites Houston-Bush Intercontinental Aprt

La Quinta Inn & Suites by Wyndham Houston Bush IAH South

La Quinta Inn & Suites by Wyndham Houston Bush IAH South
3.0 star property
Houston
8.2 out of 10, Very good, (1,526 reviews)
"This was a great place to stay and at a good price "
United States
Ashley
The price is S$107
includes taxes & fees
23 Mar - 24 Mar
La Quinta Inn & Suites by Wyndham Houston Bush IAH South

Palace Inn Blue Houston East Beltway 8

Palace Inn Blue Houston East Beltway 8
2.5 star property
Northeast Houston
9.0 out of 10, Wonderful, (365 reviews)
"Hotel was very clean, decor was great, guest services was prompt and courteous. We will def stay coming through Houston again "
United States
Desiree
The price is S$93
includes taxes & fees
25 Feb - 26 Feb
Palace Inn Blue Houston East Beltway 8

SpringHill Suites by Marriott Houston Intercontinental Arprt

SpringHill Suites by Marriott Houston Intercontinental Arprt
3.0 star property
Houston
9.0 out of 10, Wonderful, (1,667 reviews)
"Great place to stay "
United States
Andrea
The price is S$163
includes taxes & fees
15 Mar - 16 Mar
SpringHill Suites by Marriott Houston Intercontinental Arprt

Best Western Plus Manvel Inn & Suites

Best Western Plus Manvel Inn & Suites
2.5 star property
Manvel
8.8 out of 10, Excellent, (759 reviews)
"Everyone everything Awesome enjoyed my stay."
United States
Bernadette
The price is S$120
includes taxes & fees
12 Mar - 13 Mar
Best Western Plus Manvel Inn & Suites

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,117 reviews)
"Excellent stay!"
United States
Travis
The price is S$276
includes taxes & fees
22 Feb - 23 Feb
The Westin Houston Medical Center/Museum District

Hotel Park Place

Hotel Park Place
2.5 star property
Southeast Houston
8.8 out of 10, Excellent, (271 reviews)
"I had a nice stay"
United States
Christopher
The price is S$88
includes taxes & fees
22 Feb - 23 Feb
Hotel Park Place

Moxy Houston Downtown

Moxy Houston Downtown
3.0 star property
Downtown Houston
8.8 out of 10, Excellent, (769 reviews)
"great location "
United States
Yanira
The price is S$191
includes taxes & fees
22 Feb - 23 Feb
Moxy Houston Downtown

Hilton Garden Inn Houston/Bush Intercontinental Airport

Hilton Garden Inn Houston/Bush Intercontinental Airport
3.0 star property
Houston
8.4 out of 10, Very good, (1,009 reviews)
"Place was amazing and the staff were great!!!"
United States
Marlene
The price is S$155
includes taxes & fees
15 Mar - 16 Mar
Hilton Garden Inn Houston/Bush Intercontinental Airport

Doubletree by Hilton Houston Hobby Airport

Doubletree by Hilton Houston Hobby Airport
4.0 star property
Southeast Houston
8.8 out of 10, Excellent, (1,010 reviews)
"Excellent stay! The room was very clean and comfortable, and the staff went above and beyond to be friendly and helpful. Check-in was smooth, the amenities were great, and the overall atmosphere made it a relaxing experience. I’d definitely stay here again!"
United States
Wayne
The price is S$171
includes taxes & fees
2 Mar - 3 Mar
Doubletree by Hilton Houston Hobby Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

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