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Hotels in South Main

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11 Aug - 12 Aug
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12 Aug - 13 Aug
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15 Aug - 17 Aug
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Top 10 Hotels in South Main

Wyndham Houston near NRG Park/Medical Center
Lobby

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1140)
"A well kept hotel with great service and atmosphere."
The price is S$194
includes taxes & fees
13 Aug - 14 Aug
Wyndham Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical Center
Gazebo

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (930)
"Great location, rooms were hot/warm. Needs a huge make over."
The price is S$164
includes taxes & fees
13 Aug - 14 Aug
Wingate Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1002)
"Wonderful experience absolutely love my stay"
The price is S$100
includes taxes & fees
24 Aug - 25 Aug
Quality Inn & Suites NRG Park - Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (788)
"Will definitely be back again!"
The price is S$117
includes taxes & fees
22 Aug - 23 Aug
Candlewood Suites Houston Medical Center by IHG
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

4.0 star property
9.0 out of 10, Wonderful, (1020)
"Great stay!"
The price is S$192
includes taxes & fees
14 Aug - 15 Aug
Hyatt Regency Houston/Galleria
Hyatt Place Houston Medical Center
Lobby

Hyatt Place Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1882)
"Very nice hotel, clean and comfortable. "
The price is S$156
includes taxes & fees
29 Aug - 30 Aug
Hyatt Place Houston Medical Center
Blossom Hotel Houston
Front of property

Blossom Hotel Houston

4.0 star property
9.0 out of 10, Wonderful, (3467)
"I had a wonderful stay I can't wait to get back"
The price is S$199
includes taxes & fees
11 Sept - 12 Sept
Blossom Hotel Houston
Omni Houston Hotel
Interior

Omni Houston Hotel

4.0 star property
9.0 out of 10, Wonderful, (1010)
"Great place to stay Very relaxing out-of-the-way Great feel with a great swimming pool"
The price is S$231
includes taxes & fees
24 Aug - 25 Aug
Omni Houston Hotel
Hyatt Regency Houston West
Breakfast, lunch, brunch served; American cuisine, garden views

Hyatt Regency Houston West

3.5 star property
8.6 out of 10, Excellent, (1142)
"Nice rooms, plenty of food choices."
The price is S$131
includes taxes & fees
12 Sept - 13 Sept
Hyatt Regency Houston West
Holiday Inn Express & Suites Houston – Downtown North by IHG
Exterior

Holiday Inn Express & Suites Houston – Downtown North by IHG

2.5 star property
9.2 out of 10, Wonderful, (550)
"Great place to stay close to downtown "
The price is S$143
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express & Suites Houston – Downtown North by IHG
Hyatt House Houston Medical Center
Lobby

Hyatt House Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1072)
"We loved our stay. Great room, staff, and service."
The price is S$156
includes taxes & fees
22 Aug - 23 Aug
Hyatt House Houston Medical Center
The Lancaster Hotel
Exterior

The Lancaster Hotel

4.0 star property
9.6 out of 10, Exceptional, (1005)
"Beautiful hotel located downtown next to several venues and restaurants. Highly recommend if staying downtown."
The price is S$348
includes taxes & fees
21 Aug - 22 Aug
The Lancaster Hotel
The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.6 out of 10, Excellent, (1667)
"Great stay"
The price is S$215
includes taxes & fees
29 Aug - 30 Aug
The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.2 out of 10, Very good, (2364)
"Enjoyed staff and location "
The price is S$164
includes taxes & fees
10 Sept - 11 Sept
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Haven Inn & Suites Downtown Houston
Premium bedding, desk, iron/ironing board, free WiFi

Haven Inn & Suites Downtown Houston

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Great stay"
Haven Inn & Suites Downtown Houston
Heights House Hotel - Houston Heights Downtown, Ascend Hotel Collection
View from room

Heights House Hotel - Houston Heights Downtown, Ascend Hotel Collection

3.0 star property
8.0 out of 10, Very good, (1003)
"My favorite part of my experience was the staff"
The price is S$127
includes taxes & fees
1 Sept - 2 Sept
Heights House Hotel - Houston Heights Downtown, Ascend Hotel Collection
La Quinta Inn & Suites by Wyndham Houston Southwest
Exterior

La Quinta Inn & Suites by Wyndham Houston Southwest

3.0 star property
6.8 out of 10, (1008)
"I enjoyed my stay, room was very clean d"
The price is S$92
includes taxes & fees
14 Aug - 15 Aug
La Quinta Inn & Suites by Wyndham Houston Southwest
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.4 out of 10, Very good, (1179)
"Very nice hotel in a premium location!!!"
The price is S$198
includes taxes & fees
17 Aug - 18 Aug
The Royal Sonesta Houston Galleria
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very good, (410)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is S$173
includes taxes & fees
24 Aug - 25 Aug
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Club Quarters Hotel Downtown, Houston
Lobby

Club Quarters Hotel Downtown, Houston

4.0 star property
8.4 out of 10, Very good, (3593)
"Great Stay"
The price is S$158
includes taxes & fees
14 Aug - 15 Aug
Club Quarters Hotel Downtown, Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
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Downtown Houston map

Downtown Houston

3 out of top 10 points of interest in this area

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria map

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center map

Texas Medical Center

1 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Heights map

Houston Heights

You'll enjoy the coffee shops and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum.

Houston showing a city and a skyscraper
Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

10/10 Excellent
"I stay at Hyatt Regency often but this was my first at Galleria in HTx and it did not support. Open lobby area with bar and cafe, pool and fitness center. You can order food + drinks by the pool. The room is spacious and upon entering I could smell a slight bleach scent; this is typically a good indicator that the room has been cleaned properly. There were no issues with hair, stains or anything. Housekeeping will greet you in the hallways and they seem to be happy and pleasant. The front desk staff and bartenders are warm and welcoming. Parking is plenty but the parking fees can add up."
Aunnalise 4-night trip
Posted 9 hours ago
Hyatt Regency Houston/Galleria

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 55 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.