A calm lake surrounded by trees and vegetation.

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Check availability on Southwest Illinois Luxury Hotels

Tonight
10 Oct - 11 Oct
Tomorrow
11 Oct - 12 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Southwest Illinois luxury hotels

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Indulge in a luxurious retreat featuring a full-service spa, indoor pool, and casino gaming in the heart of Carterville.
S$165
includes taxes & fees
13 Oct - 14 Oct
Walker's Bluff Casino Resort
A hotel entrance with a modern design, featuring a prominent 'HOTEL' sign above the entrance.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

2. The Riverview

The Riverview
Cape Girardeau
S$154
includes taxes & fees
20 Oct - 21 Oct
The Riverview
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.
A modern building with a unique, curved roof structure.

3. The Cheshire

The Cheshire
Richmond Heights
S$226
includes taxes & fees
1 Nov - 2 Nov
The Cheshire
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.

4. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
S$281
includes taxes & fees
1 Nov - 2 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A spa bath with a sign indicating a capacity of 8 persons.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

5. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
S$199
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel St. Louis Brentwood
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.

6. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this city centre St. Louis hotel with spa services and indoor pool.
S$222
includes taxes & fees
1 Nov - 2 Nov
21C Museum Hotel St Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bakery display case with various pastries and cakes.

7. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
S$289
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
S$561
includes taxes & fees
12 Oct - 13 Oct
Four Seasons Hotel St Louis
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Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"This was the best hotel I’ve stayed in. The accommodations were outstanding with wonderful people managing the desk! Two young ladies helped us and it was amazing!"
Gina 1-night trip
Posted 11 hours ago
Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"Would stay there again"
Lidia 1-night trip
Posted 12 hours ago
Quality Inn O'Fallon - St. Louis - Shiloh
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Lovely 3 night stay. Was greeted with a warm welcome, invited for happy hour and a dinner if we did not eat yet! Suite was clean, pool and hot tub area were clean as well. If in area again we will definitely book here!!!"
Jason 3-night trip
Posted 13 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Of all the hotels I stayed at, these were probably the most comfortable beds I have ever slept in. Rooms for very clean. Pool area was nice. My would maybe suggest a few more options for the breakfast but what they did have was good."
Jennifer 1-night trip
Posted 14 hours ago
Comfort Suites Mount Vernon
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

10/10 Excellent
"Our room was very nice & bed was comfortable Easy free parking & close to highway"
Victor 1-night trip
Posted 3 days ago
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent
"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."
Lisa 3-night trip
Posted 13 days ago
Country Inn & Suites by Radisson, Marion, IL

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