Penrose
St. Louis
Popular places to visit
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Dome at America’s Center
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Small Group Tour With Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch
St Louis Self-Guided Driving and Walking Audio Tour
Top hotels in Penrose
21C Museum Hotel St Louis
Pleasant staff
Reviewed on 17 Feb, 2026
Clayton Plaza Hotel & Extended Stay
Love it
Reviewed on 17 Feb, 2026
Pear Tree Inn St. Louis Airport
We felt very welcome when we arrived and were invited to some popcorn and soda as an evening snack. Our room was spotless and comfortable. The breakfast was delicious, hot, and a terrific way to begin our day of travel.
Reviewed on 17 Feb, 2026
Drury Plaza Hotel St. Louis at the Arch
The room was spotless and staff were outstanding. This is our first stay at a Drury Hotel and we will now seek them out when traveling.
Reviewed on 16 Feb, 2026
Hyatt Regency St. Louis at The Arch
Love the view, spacious and clean room.
Reviewed on 15 Feb, 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Everything was good
Reviewed on 16 Feb, 2026
Other neighbourhoods around Penrose
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
