S$520 Cheap Flights from San Francisco to Santiago

View S$520 flight on Mon, 9 Feb, 2026Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Santiago Intl. Airport (SCL)

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Cheap Flights from San Francisco to Santiago (SFO-SCL)

Prices were available within the past 7 days and start at S$520 for one-way flights and S$581 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Mon, 27 Oct - Mon, 10 Nov
SFO
San Francisco
SCL
Santiago
S$581 Return, found 1 day ago
S$581
Return
found 1 day ago
Select Copa flight, departing Mon, 27 Oct from San Francisco to Santiago, returning Mon, 10 Nov, priced at S$581 found 1 day ago
Delta
Thu, 13 Nov - Mon, 24 Nov
SFO
San Francisco
SCL
Santiago
S$755 Return, found 1 day ago
S$755
Return
found 1 day ago
Select Delta flight, departing Thu, 13 Nov from San Francisco to Santiago, returning Mon, 24 Nov, priced at S$755 found 1 day ago
LATAM Airlines Group
Thu, 13 Nov - Mon, 24 Nov
SFO
San Francisco
SCL
Santiago
S$792 Return, found 1 day ago
S$792
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Thu, 13 Nov from San Francisco to Santiago, returning Mon, 24 Nov, priced at S$792 found 1 day ago
LATAM Airlines Group
Mon, 27 Oct - Mon, 10 Nov
SFO
San Francisco
SCL
Santiago
S$799 Return, found 1 day ago
S$799
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Mon, 27 Oct from San Francisco to Santiago, returning Mon, 10 Nov, priced at S$799 found 1 day ago
LATAM Airlines Group
Mon, 27 Oct - Mon, 10 Nov
SFO
San Francisco
SCL
Santiago
S$805 Return, found 1 day ago
S$805
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Mon, 27 Oct from San Francisco to Santiago, returning Mon, 10 Nov, priced at S$805 found 1 day ago
LATAM Airlines Group
Mon, 27 Oct - Mon, 10 Nov
SFO
San Francisco
SCL
Santiago
S$811 Return, found 1 day ago
S$811
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Mon, 27 Oct from San Francisco to Santiago, returning Mon, 10 Nov, priced at S$811 found 1 day ago
United
Mon, 9 Feb - Thu, 19 Feb
SFO
San Francisco
SCL
Santiago
S$832 Return, found 1 day ago
S$832
Return
found 1 day ago
Select United flight, departing Mon, 9 Feb from San Francisco to Santiago, returning Thu, 19 Feb, priced at S$832 found 1 day ago
American Airlines
Thu, 13 Nov - Mon, 24 Nov
SFO
San Francisco
SCL
Santiago
S$832 Return, found 1 day ago
S$832
Return
found 1 day ago
Select American Airlines flight, departing Thu, 13 Nov from San Francisco to Santiago, returning Mon, 24 Nov, priced at S$832 found 1 day ago
United
Thu, 13 Nov - Mon, 24 Nov
SFO
San Francisco
SCL
Santiago
S$875 Return, found 1 day ago
S$875
Return
found 1 day ago
Select United flight, departing Thu, 13 Nov from San Francisco to Santiago, returning Mon, 24 Nov, priced at S$875 found 1 day ago
United
Thu, 13 Nov - Mon, 24 Nov
SFO
San Francisco
SCL
Santiago
S$883 Return, found 1 day ago
S$883
Return
found 1 day ago
Select United flight, departing Thu, 13 Nov from San Francisco to Santiago, returning Mon, 24 Nov, priced at S$883 found 1 day ago

Find the cheapest month to fly from San Francisco (SFO) to Santiago (SCL)

March is typically the cheapest month to fly

From S$699 - S$1,109 per traveller.

Frequently asked questions

How much is a flight from San Francisco Intl. Airport (SFO) to SCL?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip flight between San Francisco Intl. Airport (SFO) and Nuevo Pudahuel Airport was S$581. Cheap tickets don't hang around forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Santiago International Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.
How do I find cheap flights from San Francisco Airport to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for San Francisco Airport to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to Santiago International Airport?
The distance is around 9,500 kilometres, so pack your carry-on bag with everything you need to make your journey comfortable. Not sure what to take on board your San Francisco to Santiago flight? A sleep mask, earplugs and a travel pillow are among the essentials.
Which airlines fly direct from SFO to SCL?
Unfortunately, there are no airlines that fly directly between SFO and Santiago International Airport. You'll have to book a flight with one or more stops.
Are San Francisco Airport to Arturo Merino Benitez Airport (SCL) flight tickets cheaper when they're purchased at the last minute?
Late planners can occasionally find a bargain, with some super cheap fares from SFO to Santiago International Airport emerging a few weeks prior to the departure date. If you'd rather plan ahead of time, Expedia compares and updates the best flight deals continuously — as early as 12 months in advance in some cases. It does depend on the carrier though, as not all airlines publish prices that far in advance.

Travel information

Travel information

Origin airport
San Francisco Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca
Return price
S$580
Distance
9474 km

Book with confidence

Book with confidence

Perfect flights from San Francisco to Santiago

Your Journey from San Francisco to Santiago

Start your unforgettable journey with Expedia. Our broad selection of flights from San Francisco to Santiago caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including United, Delta, Air Canada, LATAM Airlines Group, Copa, American Airlines. Our selection of flights from San Francisco Intl. to Arturo Merino Benitez caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with San Francisco to Santiago Flights

Experience the joy of finding cheap flights from San Francisco Intl. to Arturo Merino Benitez that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$520 and roundtrip prices from S$581*.
 

Pre-Flight Essentials

Ensure a smooth journey from San Francisco to Santiago with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Santiago

Picture yourself stepping off the plane in Santiago and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your San Francisco to Santiago Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from San Francisco to Santiago.
 

Beyond the Flight – Exploring Santiago

With Expedia, your adventure extends beyond the flight. Explore Santiago at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from San Francisco to Santiago with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from San Francisco to Santiago with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.
Perfect flights from San Francisco to Santiago

Explore a world of travel with Expedia

Explore a world of travel with Expedia

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