S$444 Cheap Flights from San Francisco to Santiago

View S$444 flight on Mon, 29 Dec, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Santiago Intl. Airport (SCL)

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Cheap Flights from San Francisco to Santiago (SFO-SCL)

Prices were available within the past 7 days and start at S$444 for one-way flights and S$858 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$858 Return, found 2 days ago
S$858
Return
found 2 days ago
Select Copa flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$858 found 2 days ago
Copa
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$871 Return, found 2 days ago
S$871
Return
found 2 days ago
Select Copa flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$871 found 2 days ago
Copa
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$880 Return, found 2 days ago
S$880
Return
found 2 days ago
Select Copa flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$880 found 2 days ago
Copa
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$884 Return, found 2 days ago
S$884
Return
found 2 days ago
Select Copa flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$884 found 2 days ago
Copa
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$897 Return, found 2 days ago
S$897
Return
found 2 days ago
Select Copa flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$897 found 2 days ago
Copa
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$906 Return, found 2 days ago
S$906
Return
found 2 days ago
Select Copa flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$906 found 2 days ago
Delta
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$949 Return, found 2 days ago
S$949
Return
found 2 days ago
Select Delta flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$949 found 2 days ago
avianca
Sun, 13 Jul - Tue, 29 Jul
SFO
San Francisco
SCL
Santiago
S$1,085 Return, found 1 day ago
S$1,085
Return
found 1 day ago
Select avianca flight, departing Sun, 13 Jul from San Francisco to Santiago, returning Tue, 29 Jul, priced at S$1,085 found 1 day ago
American Airlines
Wed, 6 Aug - Wed, 13 Aug
SFO
San Francisco
SCL
Santiago
S$1,146 Return, found 2 days ago
S$1,146
Return
found 2 days ago
Select American Airlines flight, departing Wed, 6 Aug from San Francisco to Santiago, returning Wed, 13 Aug, priced at S$1,146 found 2 days ago
Air Canada
Sat, 13 Dec - Wed, 17 Dec
SFO
San Francisco
SCL
Santiago
S$1,388 Return, found 2 days ago
S$1,388
Return
found 2 days ago
Select Air Canada flight, departing Sat, 13 Dec from San Francisco to Santiago, returning Wed, 17 Dec, priced at S$1,388 found 2 days ago

Find the cheapest month to fly from San Francisco (SFO) to Santiago (SCL)

August is typically the cheapest month to fly

From S$677 - S$1,115 per traveller.

Graph displaying average flight prices per month

San Francisco to Santiago route information
Origin airport
San Francisco Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, Air Canada, American Airlines, Copa, Delta, United, avianca
Return price
S$858
Distance
9474 km

Perfect flights from San Francisco to Santiago

Your Journey from San Francisco to Santiago

Start your unforgettable journey with Expedia. Our broad selection of flights from San Francisco to Santiago caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including Copa, avianca, Delta, United, Air Canada, American Airlines. Our selection of flights from San Francisco Intl. to Arturo Merino Benitez caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with San Francisco to Santiago Flights

Experience the joy of finding cheap flights from San Francisco Intl. to Arturo Merino Benitez that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$444 and roundtrip prices from S$858*.
 

Pre-Flight Essentials

Ensure a smooth journey from San Francisco to Santiago with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Santiago

Picture yourself stepping off the plane in Santiago and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your San Francisco to Santiago Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from San Francisco to Santiago.
 

Beyond the Flight – Exploring Santiago

With Expedia, your adventure extends beyond the flight. Explore Santiago at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from San Francisco to Santiago with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from San Francisco to Santiago with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from San Francisco Intl. Airport (SFO) to SCL?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip flight between San Francisco Intl. Airport (SFO) and Nuevo Pudahuel Airport was S$858. Cheap tickets don't hang around forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Santiago International Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.
How do I find cheap flights from San Francisco Airport to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for San Francisco Airport to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to Santiago International Airport?
The distance is around 9,500 kilometres, so pack your carry-on bag with everything you need to make your journey comfortable. Not sure what to take on board your San Francisco to Santiago flight? A sleep mask, earplugs and a travel pillow are among the essentials.
Which airlines fly direct from SFO to SCL?
Unfortunately, there are no airlines that fly directly between SFO and Santiago International Airport. You'll have to book a flight with one or more stops.
Are San Francisco Airport to Arturo Merino Benitez Airport (SCL) flight tickets cheaper when they're purchased at the last minute?
Late planners can occasionally find a bargain, with some super cheap fares from SFO to Santiago International Airport emerging a few weeks prior to the departure date. If you'd rather plan ahead of time, Expedia compares and updates the best flight deals continuously --- as early as 12 months in advance in some cases. It does depend on the carrier though, as not all airlines publish prices that far in advance.

Explore a world of travel with Expedia

*Available to Expedia members.