S$388 Cheap Flights from San Francisco to Santiago

View S$388 flight on Wed, 21 Jan, 2026Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Santiago Intl. Airport (SCL)

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Cheap Flights from San Francisco to Santiago (SFO-SCL)

Prices were available within the past 7 days and start at S$388 for one-way flights and S$763 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, 27 Nov - Wed, 10 Dec
SFO
San Francisco
SCL
Santiago
S$763 Return, found 2 days ago
S$763
Return
found 2 days ago
Select Delta flight, departing Thu, 27 Nov from San Francisco to Santiago, returning Wed, 10 Dec, priced at S$763 found 2 days ago
Delta
Fri, 28 Nov - Thu, 11 Dec
SFO
San Francisco
SCL
Santiago
S$779 Return, found 1 day ago
S$779
Return
found 1 day ago
Select Delta flight, departing Fri, 28 Nov from San Francisco to Santiago, returning Thu, 11 Dec, priced at S$779 found 1 day ago
LATAM Airlines Group
Thu, 27 Nov - Wed, 10 Dec
SFO
San Francisco
SCL
Santiago
S$801 Return, found 2 days ago
S$801
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, 27 Nov from San Francisco to Santiago, returning Wed, 10 Dec, priced at S$801 found 2 days ago
Delta
Thu, 27 Nov - Wed, 10 Dec
SFO
San Francisco
SCL
Santiago
S$811 Return, found 2 days ago
S$811
Return
found 2 days ago
Select Delta flight, departing Thu, 27 Nov from San Francisco to Santiago, returning Wed, 10 Dec, priced at S$811 found 2 days ago
LATAM Airlines Group
Thu, 27 Nov - Wed, 10 Dec
SFO
San Francisco
SCL
Santiago
S$814 Return, found 2 days ago
S$814
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, 27 Nov from San Francisco to Santiago, returning Wed, 10 Dec, priced at S$814 found 2 days ago
LATAM Airlines Group
Fri, 28 Nov - Thu, 11 Dec
SFO
San Francisco
SCL
Santiago
S$817 Return, found 1 day ago
S$817
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 28 Nov from San Francisco to Santiago, returning Thu, 11 Dec, priced at S$817 found 1 day ago
Delta
Sat, 14 Mar - Fri, 20 Mar
SFO
San Francisco
SCL
Santiago
S$818 Return, found 2 days ago
S$818
Return
found 2 days ago
Select Delta flight, departing Sat, 14 Mar from San Francisco to Santiago, returning Fri, 20 Mar, priced at S$818 found 2 days ago
American Airlines
Thu, 27 Nov - Wed, 10 Dec
SFO
San Francisco
SCL
Santiago
S$841 Return, found 2 days ago
S$841
Return
found 2 days ago
Select American Airlines flight, departing Thu, 27 Nov from San Francisco to Santiago, returning Wed, 10 Dec, priced at S$841 found 2 days ago
Copa
Thu, 27 Nov - Wed, 10 Dec
SFO
San Francisco
SCL
Santiago
S$861 Return, found 2 days ago
S$861
Return
found 2 days ago
Select Copa flight, departing Thu, 27 Nov from San Francisco to Santiago, returning Wed, 10 Dec, priced at S$861 found 2 days ago
United
Fri, 28 Nov - Thu, 11 Dec
SFO
San Francisco
SCL
Santiago
S$916 Return, found 1 day ago
S$916
Return
found 1 day ago
Select United flight, departing Fri, 28 Nov from San Francisco to Santiago, returning Thu, 11 Dec, priced at S$916 found 1 day ago

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Find the cheapest month to fly from San Francisco (SFO) to Santiago (SCL)

October is typically the cheapest month to fly

From S$604 - S$1,043 per traveller.
San Francisco to Santiago route information
Origin airport
San Francisco Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United
Return price
S$763
Distance
9474 km

Perfect flights from San Francisco to Santiago

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*Note: Prices may vary based on availability and are subject to change.

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