A red train on tracks, palm trees, and modern buildings.

Find Central San Diego Spa Hotels from S$137

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Check availability on Central San Diego Hotels with Spa

Tonight
16 Sept - 17 Sept
Tomorrow
17 Sept - 18 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Our top choices for Central San Diego hotels with a spa

A hotel with a curved entrance, palm trees, and a parking lot.
A lobby with seating areas, a piano, and a reception desk.
A spacious lobby with a central round table, a reception desk, and a bar area.
A resort with a large swimming pool surrounded by lounge chairs and palm trees.

1. Handlery Hotel

Handlery Hotel
Mission Valley
  • Surrender to spa treatments and poolside luxury at this hotel with massage rooms and a beautiful heated outdoor pool and hot tub.
S$174
includes taxes & fees
20 Sept - 21 Sept
Handlery Hotel
A modern bathroom with a shower, a towel rack, and a bench.
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A pathway leading to a building labeled "LEGACY Hotel."
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.

2. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
  • Indulge in a serene escape at this upscale hotel with a full-service spa, outdoor pool with free cabanas, and couples massage treatments.
S$256
includes taxes & fees
27 Sept - 28 Sept
Legacy Resort Hotel & Spa
An aerial view of a resort with a central swimming pool, palm trees, and a view of the ocean and beach.
An outdoor dining area with tables and chairs, umbrellas, and string lights against a sunset backdrop.
A waterfront hotel with a dock, palm trees, and a view of the water.
A modern building with a curved roof, surrounded by lush tropical vegetation.

3. Paradise Point Resort & Spa

Paradise Point Resort & Spa
Mission Bay
  • Immerse in waterfront tranquility with hot stone massages and aromatherapy at this resort spa retreat.
S$382
includes taxes & fees
4 Oct - 5 Oct
Paradise Point Resort & Spa
A reception area with a mirror, decorative plants, a wooden bench, and a hanging light fixture.
An outdoor dining area with brick flooring, wicker furniture, and a stone wall.
A balcony with wicker furniture and a small table, overlooking a courtyard with palm trees and a building with balconies.
A spacious lobby with a high ceiling, wooden beams, a fireplace, and comfortable seating areas.

4. Estancia La Jolla Hotel & Spa

Estancia La Jolla Hotel & Spa
La Jolla Farms
  • Discover a tranquil garden retreat with luxurious spa treatments and a serene outdoor pool for the ultimate pampering getaway in La Jolla.
S$511
includes taxes & fees
27 Sept - 28 Sept
Estancia La Jolla Hotel & Spa
A modern building with a sloped roof and large windows, surrounded by palm trees and a well-maintained garden.
A hotel entrance with a modern design, palm trees, and a sign indicating it is part of the Best Western Plus chain.
A spacious lobby with a high ceiling, stone flooring, and wicker furniture.
An outdoor patio with round tables and chairs, large umbrellas, and a marina view in the background.

5. Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
Point Loma
  • Blissful bay views and relaxing massages set the scene for a restorative escape at this waterfront sanctuary with bubbling hot tubs.
S$216
includes taxes & fees
30 Sept - 1 Oct
Best Western Plus Island Palms Hotel & Marina
A spacious lobby with a reception desk, seating area, and artwork on the walls.
A resort pool with a lazy river, palm trees, and a view of the ocean.
A marina with boats docked, a covered outdoor dining area with red chairs and tables, and a view of the marina in the background.
A modern hotel room with a large window offering a view of the sea, a sofa, a dining table, and a TV on a wooden cabinet.

6. Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
Mission Bay
  • Experience coastal tranquility at this spa hotel with bay views, heated pools, and waterslides.
S$359
includes taxes & fees
30 Sept - 1 Oct
Hyatt Regency Mission Bay Spa and Marina
A spacious lobby with a reception desk, seating area, and a stone wall.
A resort with two-story buildings, balconies, and a pool area.
A restaurant with a view of a marina, featuring high ceilings, modern lighting, and a central chandelier.
A marina with wooden tables and chairs, umbrellas, and a view of boats and city lights in the background.

7. Humphreys Half Moon Inn

Humphreys Half Moon Inn
Point Loma
  • Escape to this bayfront sanctuary with deep-tissue massages, a serene hot tub, and an outdoor pool for complete relaxation.
S$302
includes taxes & fees
5 Oct - 6 Oct
Humphreys Half Moon Inn
A spacious indoor area with large windows overlooking the ocean, featuring modern furniture and a wooden floor.
A poolside area with sun loungers and white canopies, palm trees in the background, and a clear sky.
A staircase leading to a beach with umbrellas and people in the water.
A sunlit outdoor area with a curved staircase leading to a beach view, outdoor seating, and a palm tree.

8. La Jolla Beach and Tennis Club

La Jolla Beach and Tennis Club
La Jolla Shores
  • Mediterranean beachfront wellness awaits with private spa cabanas, golf course, and beach access for total rejuvenation.
S$366
includes taxes & fees
24 Sept - 25 Sept
La Jolla Beach and Tennis Club
A person sitting by a pool with a tiled floor and a marble wall.
A modern lounge area with dark-toned seating, a central coffee table, and a stone accent wall.
A modern bar area with a long counter, multiple stools, and a variety of bottles on shelves.
A modern hotel with a prominent entrance, multiple floors, and a landscaped area with palm trees and a bridge.

9. Sycuan Casino Resort

Sycuan Casino Resort
El Cajon
  • Escape to a luxurious mountain retreat with 10 treatment rooms and outdoor pools, where hot stone massages and aromatherapy await.
S$137
includes taxes & fees
15 Oct - 16 Oct
Sycuan Casino Resort
A dining area with a checkered floor, wooden chairs, a marble table, and a view of tropical foliage through large windows.
A couple walking through a wooden door into a building with a tropical garden view.
A room with a large glass door leading to a grassy deck with a table and chairs, overlooking a marina with boats and a clear sky.
An outdoor patio with seating, a fire pit, and a view of the ocean.

10. Catamaran Resort and Spa

Catamaran Resort and Spa
Mission Beach
  • Luxurious beachside retreat offers 10 spa treatment rooms, waterfront yoga, and a serene bay location for ultimate wellness.
S$430
includes taxes & fees
20 Sept - 21 Sept
Catamaran Resort and Spa
View all properties

Choose what matters most at spa hotels in Central San Diego

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Central San Diego Hotel Reviews

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

10/10 Excellent
"A nice size room. My son loved the space downstairs and seeing the fish. A shame we had to pay for parking, especially as the parking lot was often full and I couldn’t find a spot."
Shaina 3-night trip
Posted 2 hours ago
Embassy Suites by Hilton San Diego La Jolla
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

10/10 Excellent
"clean and good ambience loved it"
MARGARITA 1-night trip
Posted 11 hours ago
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"They were super clean , friendly , kind"
Susan 2-night trip
Posted 12 hours ago
The Alcala Hotel Mission Valley/Seaworld
Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA

10/10 Excellent
"We are coming to this hotel every year . We enjoying clean rooms, big breakfast and good location. We recommended this hotel to many people and nobody was disappointed. We will come next year again. Highly recommended."
Alexander 5-night trip
Posted 14 hours ago
Country Inn & Suites by Radisson, San Diego North, CA
Handlery Hotel

Handlery Hotel

10/10 Excellent
"The experience is amazing is amazing , worth every penny we spent clean , pool and hot tub awsome staff friendly and helpful location near everything I will be back again !!!"
James 5-night trip
Posted 16 hours ago
Handlery Hotel
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

8/10 Good
"the room was clean. had a great view of the courtyard and pool. The staff was great! Could have used some creamer for the coffee machine."
Nericia 2-night trip
Posted 18 hours ago
Crowne Plaza San Diego - Mission Valley by IHG
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

10/10 Excellent
"Location"
Vilma 1-night trip
Posted 2 days ago
Hampton Inn San Diego/Mission Valley

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