Search Mississippi County Hotels

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
10 Oct - 12 Oct
Next weekend
17 Oct - 19 Oct

Filter by

Guest rating
Guest rating
Star rating

Top Hotels in Mississippi County

Super 8 by Wyndham Charleston/Sikeston East MO
Front of property – evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (593)
"Thank you!!!"
The price is S$81
includes taxes & fees
12 Oct - 13 Oct
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (403)
"I consistently choose to stay there due to positive past encounters."
The price is S$89
includes taxes & fees
2 Nov - 3 Nov
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (101)
"Comfortable bed, easy access to room"
The price is S$104
includes taxes & fees
7 Oct - 8 Oct
Eagle Inn Charleston
Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (270)
"Break fast was excellent "
The price is S$97
includes taxes & fees
13 Oct - 14 Oct
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mississippi County Hotel Reviews

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

10/10 Excellent
"Clean"
Steve 3-night trip
Posted 1 day ago
Pear Tree Inn Sikeston

Explore a world of travel with Expedia

Explore a world of travel with Expedia