A bridge over a muddy river with green trees and hills in the background.

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Top Cities in Mississippi County

A sunset over a calm lake with tall trees reflected in the water.
HotelsHotels

Charleston

Charleston
A tree-lined landscape with a river and fields.
HotelsHotels

East Prairie

East Prairie

Check prices for these dates

This weekend
31 Jul - 2 Aug
Next weekend
7 Aug - 9 Aug

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Our top choices for Mississippi County hotels

Breakfast included
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (651 reviews)
"The room was spacious and could have used a small loveseat for TV watching. The breakfast didn't include pastries or a waffle machine. There's instant oatmeal and apples, OJ, coffee and apple juice. I'm hoping as they continue to renovate it will be like other hotels I've stayed at for the same price."
United States
France
The price is S$85
includes taxes & fees
16 Aug - 17 Aug
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (422 reviews)
"Staff was excellent. It was fine for what it was — a cheap place near the highway"
United States
Emily
The price is S$102
includes taxes & fees
2 Aug - 3 Aug
The Riverstone Hotel Charleston-Sikeston
View from room

3. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is S$99
includes taxes & fees
1 Aug - 2 Aug
Eagle Inn Charleston
Lobby

4. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (292 reviews)
"Breakfast was sparse. This motel needs a complete overhaul. "
United States
Susan
The price is S$98
includes taxes & fees
14 Aug - 15 Aug
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent
"It's a block off the main drag, but wasn't hard to find. Elevator was noisy enough that we preferred the stairs but never had a problem with it. Stairs were carpeted and nice. They had a surprise $50 incidental fee they charged at checkin which surprised us, none of the other ones on our trip did that. now I have to watch for a refund which is annoying."
Greg 1-night trip
Posted 4 hours ago
Holiday Inn Express & Suites Sikeston Southwest by IHG

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