Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory which includes flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory which includes animals, flowers and zoo animals
South Beach which includes a coastal town and a beach as well as a large group of people
South Beach featuring a beach, swimming and a luxury hotel or resort
Key West Butterfly and Nature Conservatory which includes signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(39 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

4.5/5(8 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory featuring animals, zoo animals and food

Key West Butterfly and Nature Conservatory

4.5/5(10 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

S$22
per traveller
78% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

S$39
per adult
Bahama Village Walking Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

S$19
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

S$13
per traveller
Florida Key West Self-Guided Walking Audio Tour Via App
Southernmost Point in the Continental USA!

PRIVATE Welcome to Key West Walking Tour

S$353
per adult
PRIVATE Welcome to Key West Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

S$52
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
See all activities in Key West

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
4 out of 5
1319 Duval Street, Key West, FL
The price is S$419 per night from 23 Jun to 24 Jun
S$419
per night
23 Jun - 24 Jun
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,493 reviews)
"I like the tranquility, the cleanliness, the very friendly workers, I recommend it"

Reviewed on 8 Jun, 2025

Southernmost Beach Resort and Guesthouses
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,096 reviews)
"This property is adorable. Quiet, clean, and everyone is friendly. Half a block from Duval Street"

Reviewed on 8 Jun, 2025

Get rates
The Southernmost Inn - Adults Only
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is S$461 per night from 29 Jun to 30 Jun
S$461
per night
29 Jun - 30 Jun
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (979 reviews)
"Beautiful location and very friendly staff."

Reviewed on 8 Jun, 2025

The Reach Key West, Curio Collection by Hilton
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (1,001 reviews)
"The service was amazing! Loved having our room by the pool, in walking distance of everything we wanted to do, it was quiet even though on Duval Street. It had great amenities with all the personal care products, sunscreen, water, breakfast, happy hour, and adults only. Love our stay."

Reviewed on 2 Jun, 2025

Get rates
Orchid Key Inn - Adults Only
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
4 out of 5
1400 Duval Street, Key West, FL
The price is S$289 per night from 16 Jun to 17 Jun
S$289
per night
16 Jun - 17 Jun
Stay at this 4-star beach hotel in Key West. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,003 reviews)
"The history in the house is rich. Even though it’s on the end of Dual it was quiet and we did not have a bunch of noise when trying to sleep or seep in. Breakfast in the morning was great."

Reviewed on 5 Jun, 2025

The Mansion on the Sea - Southernmost House in the USA
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is S$225 per night from 10 Jun to 11 Jun
S$225
per night
10 Jun - 11 Jun
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,102 reviews)
"Its rundown but location is great, bar and liquor store attached to it made it fun. This isnt for luxury travel, its a place to sleep and shower but thats all you need in key west"

Reviewed on 2 Jun, 2025

Southwinds Motel
See all 2,811 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Default Image

Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.

Old Town Key West
Default Image

Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Default Image

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Default Image

Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
Default Image

White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Saint Mary Star of the Sea.

White Street Gallery District

Uptown - Upper Duval