Hotels in Midtown

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Midtown hotels

Tx Home Group- San Antonio

Tx Home Group- San Antonio
3.0 star property
Midtown
10.0 out of 10, Exceptional, (4)
"Great place to stay. Host really made you feel comfortable and welcomed. "
United States
Brian
The price is S$256
includes taxes & fees
27 Jan - 28 Jan, 2026
Tx Home Group- San Antonio

Classic 1br/1ba Charming Apt w/ Modern Upgrades

Classic 1br/1ba Charming Apt w/ Modern Upgrades
3.0 star property
Midtown
8.4 out of 10, Very good, (5)
"The property was very nice for my one-night stay. Very clean and the location was great for access to downtown San Antonio! If you are a light sleeper, I recommend bringing earplugs as the A/C unit in the bedroom was a bit loud. All in all, definitely recommend."
United States
Madison
The price is S$146
includes taxes & fees
12 Jan - 13 Jan, 2026
Classic 1br/1ba Charming Apt w/ Modern Upgrades

O'Casey's Boutique Inn

O'Casey's Boutique Inn
3.0 star property
Midtown
8.8 out of 10, Excellent, (748)
"A lovely gem of a property. Neighborhood as well. Our stay was very unique and comfortable. We liked it very much."
United States
JERRY
The price is S$211
includes taxes & fees
7 Jan - 8 Jan, 2026
O'Casey's Boutique Inn

Remodeled Historic 1BR 1BA House Near Downtown

Remodeled Historic 1BR 1BA House Near Downtown
2.0 star property
Midtown
The price is S$219
includes taxes & fees
12 Jan - 13 Jan, 2026
Remodeled Historic 1BR 1BA House Near Downtown

Remodeled Vintage Charm 1br/1ba Apt Close to DT

Remodeled Vintage Charm 1br/1ba Apt Close to DT
3.0 star property
Midtown
6.0 out of 10, (4)
"The house itself is fine. Clean and good parking. The toilet paper fixture was broken, the soap in the bathroom is cheap. They charge $200 (insane) deposit of which they decided to take $22 because i slightly stained their crappy white towels with a smudge of makeup. They claimed that they couldnt be cleaned so they deducted that from my deposit. So, be careful staining their towels "
United States
Hilda
The price is S$165
includes taxes & fees
27 Jan - 28 Jan, 2026
Remodeled Vintage Charm 1br/1ba Apt Close to DT

Stunning 2br/1ba Historic Pad Few Steps Downtown

Stunning 2br/1ba Historic Pad Few Steps Downtown
3.5 star property
Midtown
6.0 out of 10, (2)
"Location was close to downtown and met our needs. The house was clean and in good shape. Although, I think there were a few fire detectors missing. The dock was there and the detector was not. We didn't get to use the parking spot promised in the back due to concrete repair going on. But there was ample street parking. The fridge did not work when we arrived and the owner sent maintenance the next day to fix it. All in all, we had a great time."
United States
Carrie
Stunning 2br/1ba Historic Pad Few Steps Downtown

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3.0 star property
Downtown San Antonio, 3.5 km from Midtown
7.8 out of 10, Good, (3812)
"Had an amazing time at the hotel "
United States
Uriel
The price is S$130
includes taxes & fees
4 Jan - 5 Jan, 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk
2.0 star property
Downtown San Antonio, 3.1 km from Midtown
9.0 out of 10, Wonderful, (1821)
"Great hotel in a great location "
United States
Breanna
The price is S$145
includes taxes & fees
4 Jan - 5 Jan, 2026
Hotel Gibbs Downtown Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
13.7 km from Midtown
9.2 out of 10, Wonderful, (1123)
"Great clean hotel, we came in with my family happy and left happy! "
United States
Samuel
The price is S$116
includes taxes & fees
16 Jan - 17 Jan, 2026
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

Days Inn by Wyndham Suites San Antonio North/Stone Oak

Days Inn by Wyndham Suites San Antonio North/Stone Oak
2.5 star property
16.6 km from Midtown
8.0 out of 10, Very good, (1130)
"Rooms were clean "
United States
Kristina
The price is S$89
includes taxes & fees
12 Jan - 13 Jan, 2026
Days Inn by Wyndham Suites San Antonio North/Stone Oak

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
11.3 km from Midtown
8.6 out of 10, Excellent, (1237)
"Love this hotel!"
United States
Nora
The price is S$128
includes taxes & fees
23 Jan - 24 Jan, 2026
The Westin San Antonio North

Menger Hotel

Menger Hotel
3.5 star property
Downtown San Antonio, 3.3 km from Midtown
9.0 out of 10, Wonderful, (3634)
"Great, grand hotel it was wonderful stay."
United States
Brian
The price is S$152
includes taxes & fees
25 Jan - 26 Jan, 2026
Menger Hotel

Hampton Inn San Antonio-Downtown (River Walk)

Hampton Inn San Antonio-Downtown (River Walk)
2.5 star property
Downtown San Antonio, 3.2 km from Midtown
8.4 out of 10, Very good, (2412)
"Check in was great - the front desk is very friendly and place looks clean"
United States
Monica
The price is S$120
includes taxes & fees
6 Jan - 7 Jan, 2026
Hampton Inn San Antonio-Downtown (River Walk)

Tru by Hilton San Antonio North

Tru by Hilton San Antonio North
2.5 star property
22 km from Midtown
8.8 out of 10, Excellent, (633)
"Staff was very helpful n friendly. Rooms were clean and gym as well. Will definitely stay again"
United States
Cynthia
The price is S$109
includes taxes & fees
27 Jan - 28 Jan, 2026
Tru by Hilton San Antonio North

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 17.5 km from Midtown
9.0 out of 10, Wonderful, (1325)
"Beautiful location and great staff"
United States
Miguel
The price is S$168
includes taxes & fees
12 Jan - 13 Jan, 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Riverwalk Plaza

Riverwalk Plaza
4.0 star property
3.4 km from Midtown
8.2 out of 10, Very good, (6268)
"Clean room great location friendly staff"
United States
Rebecca
Riverwalk Plaza

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
25.3 km from Midtown
9.2 out of 10, Wonderful, (168)
"Very clean, convenient location, very nice staff.. "
United States
LIEZL
The price is S$104
includes taxes & fees
4 Jan - 5 Jan, 2026
Extended Stay America Premier Suites - San Antonio - Schertz

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 16.6 km from Midtown
8.2 out of 10, Very good, (1001)
"Clean room, friendly and helpful staff."
United States
Robyn
The price is S$102
includes taxes & fees
30 Jan - 31 Jan, 2026
Best Western Garden Inn

Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown, 7.7 km from Midtown
9.2 out of 10, Wonderful, (1065)
"We enjoyed the stay! Staff was super friendly. Will stay again. "
United States
Carla
The price is S$135
includes taxes & fees
4 Jan - 5 Jan, 2026
Wyndham Garden San Antonio Airport

Days Inn by Wyndham San Antonio Airport

Days Inn by Wyndham San Antonio Airport
2.0 star property
Uptown, 7.5 km from Midtown
8.0 out of 10, Very good, (1016)
"The check-in was fast and efficient. The person who checked us in was courteous and professional. "
United States
Wynonie
The price is S$78
includes taxes & fees
4 Jan - 5 Jan, 2026
Days Inn by Wyndham San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio River and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

Top Midtown Hotel Reviews

Frequently asked questions

What's it like in Midtown?
Midtown is a neighbourhood that travellers like for its riverfront, bars and libraries. Looking for sights you might find in a travel guide about Midtown? Consider a visit to San Antonio River while you're in the neighbourhood.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, O'Casey's Boutique Inn is the highest ranked property in Midtown. This B&B offers free breakfast and free parking.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in San Antonio, Expedia has something to meet your needs with 222 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals in Midtown.
What are the top things to see and do in Midtown?
If you're looking for activities to do while you're in Midtown, look into Historic Brackenridge Golf Course and McFarlin Tennis Center. As you're discovering the neighbourhood, San Antonio River and The DoSeum are some other places worth a visit. Japanese Tea Gardens, Parchman Stremmel Galleries and Button Stadim are just a few of the places to visit in and around Midtown. While you're out sightseeing in San Antonio, make sure that you visit other sights such as Brackenridge Eagle Miniature Train or Kiddie Park.

Explore a world of travel with Expedia