Hotels in Serra Mesa

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Serra Mesa

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1004)
"Had a great stay "
The price is S$158
includes taxes & fees
6 Oct - 7 Oct
Gaslamp Plaza Suites

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1271)
"Great hotel and excellent location!"
The price is S$161
includes taxes & fees
15 Oct - 16 Oct
Urban Boutique Hotel

The Sofia Hotel

3.5 star property
8.4 out of 10, Very good, (1587)
"Fantastic staff and property. "
The Sofia Hotel

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very good, (1384)
"Pleasant stay"
The Bristol Hotel San Diego

Wyndham Garden San Diego Near SeaWorld

3.0 star property
7.4 out of 10, Good, (4019)
"Really good place to stay"
The price is S$139
includes taxes & fees
9 Oct - 10 Oct
Wyndham Garden San Diego Near SeaWorld

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1894)
"Great place to stay they are right in the middle of everything "
La Pensione Hotel

Best Western Plus Bayside Inn

3.0 star property
8.8 out of 10, Excellent, (1000)
"Awesome hotel!"
The price is S$214
includes taxes & fees
12 Oct - 13 Oct
Best Western Plus Bayside Inn

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2574)
"Great location and lovely staff. "
The Horton Grand, Downtown/Gaslamp Quarter

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2970)
"Loved staying here. Will definitely stay again "
The price is S$402
includes taxes & fees
22 Oct - 23 Oct
Hard Rock Hotel San Diego

The Beau Downtown San Diego Gaslamp Quar

3.0 star property
8.8 out of 10, Excellent, (472)
"Great staff, easy check in and good location"
The price is S$168
includes taxes & fees
12 Oct - 13 Oct
The Beau Downtown San Diego Gaslamp Quar

SureStay Hotel by Best Western San Diego Pacific Beach

2.5 star property
8.0 out of 10, Very good, (1269)
"Great stay"
The price is S$115
includes taxes & fees
26 Oct - 27 Oct
SureStay Hotel by Best Western San Diego Pacific Beach

Comfort Inn Sea World Area

3.5 star property
8.6 out of 10, Excellent, (2812)
"Friendly staff, great breakfast"
The price is S$138
includes taxes & fees
13 Oct - 14 Oct
Comfort Inn Sea World Area

Heritage Inn San Diego

2.0 star property
7.2 out of 10, Good, (1031)
"Like the area around the hotel, room was well kept also. "
The price is S$98
includes taxes & fees
6 Oct - 7 Oct
Heritage Inn San Diego

Sea Harbor Hotel

2.0 star property
8.4 out of 10, Very good, (993)
"The staff are super friendly and very accommodating to our requests. "
Sea Harbor Hotel

Hotel Gigi San Diego

2.0 star property
8.4 out of 10, Very good, (366)
"Very convenient for Petco Park. Plenty of dining options within walking distance. Bring your own shampoo/soap just in case."
The price is S$135
includes taxes & fees
3 Oct - 4 Oct
Hotel Gigi San Diego

Best Western Yacht Harbor Hotel

2.5 star property
8.6 out of 10, Excellent, (1531)
"So close to so many dining options, clean and comfortable room and the pool was refreshing. Highly recommended. Thanks!!"
The price is S$149
includes taxes & fees
2 Nov - 3 Nov
Best Western Yacht Harbor Hotel

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
8.0 out of 10, Very good, (2341)
"We loved our stay, great price, very clean and excellent location! "
The price is S$145
includes taxes & fees
6 Oct - 7 Oct
Days Inn by Wyndham San Diego Hotel Circle

The Atwood Hotel San Diego - SeaWorld/Zoo

3.0 star property
7.8 out of 10, Good, (1809)
"Great customer service and decent rooms for the pricepoint."
The Atwood Hotel San Diego - SeaWorld/Zoo

Kings Inn San Diego

2.5 star property
8.8 out of 10, Excellent, (3429)
"Great place to stay!"
The price is S$120
includes taxes & fees
5 Oct - 6 Oct
Kings Inn San Diego

Handlery Hotel

3.5 star property
8.2 out of 10, Very good, (2134)
"Very nice stay"
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Serra Mesa Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 34 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.