Hotels in Serra Mesa

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Our top choices for Serra Mesa hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 10.7 km from Serra Mesa
9.0 out of 10, Wonderful, (2890)
"Excellent stay...wonderful staff"
United States
Michelle
The price is S$332
includes taxes & fees
3 Jan - 4 Jan
Manchester Grand Hyatt San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6019)
"Always an amazing stay"
United States
Jana
The price is S$233
includes taxes & fees
4 Jan - 5 Jan
Wyndham San Diego Bayside

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3186)
"Beautiful hotel"
United States
Jordan M.
Hard Rock Hotel San Diego

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
9.3 km from Serra Mesa
8.8 out of 10, Excellent, (840)
"would stay again and recommend "
United States
Brendi
The price is S$165
includes taxes & fees
4 Jan - 5 Jan
The DEXTRO Little Italy, BW Premier Collection

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.4 km from Serra Mesa
8.4 out of 10, Very good, (1938)
"Great location and will reserve again when visiting San Diego."
United States
Jason
The price is S$179
includes taxes & fees
9 Jan - 10 Jan
DoubleTree by Hilton San Diego - Del Mar

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4131)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is S$125
includes taxes & fees
22 Jan - 23 Jan
Wyndham Garden San Diego Near SeaWorld

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3192)
"The stay and staff were wonderful and very helpful.."
United States
Elsie
The price is S$231
includes taxes & fees
5 Jan - 6 Jan
Sheraton San Diego Resort

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1003)
"Great location "
United States
Mohammad
The price is S$141
includes taxes & fees
6 Jan - 7 Jan
Staypineapple, Hotel Z, Gaslamp San Diego

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
9.6 km from Serra Mesa
8.2 out of 10, Very good, (2320)
"Nice and convenient place to stay!"
United States
Esperanza
The price is S$155
includes taxes & fees
18 Jan - 19 Jan
Hampton Inn San Diego-Downtown

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 10.7 km from Serra Mesa
9.2 out of 10, Wonderful, (1970)
"Great place to stay, everything close by"
United States
Manjinder
The price is S$340
includes taxes & fees
9 Jan - 10 Jan
Marriott Marquis San Diego Marina

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
12.6 km from Serra Mesa
9.2 out of 10, Wonderful, (3240)
"Great stay and location!"
United States
Jason
The price is S$158
includes taxes & fees
4 Jan - 5 Jan
Bay Club Hotel & Marina

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 7.1 km from Serra Mesa
8.4 out of 10, Very good, (1321)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is S$271
includes taxes & fees
4 Jan - 5 Jan
San Diego Mission Bay Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
29.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1653)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
5.4 km from Serra Mesa
8.0 out of 10, Very good, (2430)
"Clean room and excellent service "
United States
Jaime
The price is S$124
includes taxes & fees
5 Jan - 6 Jan
Days Inn by Wyndham San Diego Hotel Circle

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 7.9 km from Serra Mesa
8.2 out of 10, Very good, (1923)
"Great stay "
United States
Vanessa
The price is S$135
includes taxes & fees
19 Jan - 20 Jan
Comfort Inn San Diego Old Town

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 10.1 km from Serra Mesa
9.0 out of 10, Wonderful, (3954)
"Great spot, great hotel, great food options!"
United States
Demes SP
The price is S$231
includes taxes & fees
4 Jan - 5 Jan
The Dana on Mission Bay

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1241)
"Clean, courteous staff, good location. "
United States
Carla
The price is S$232
includes taxes & fees
5 Jan - 6 Jan
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1051)
"Easy check in, clean room, the little store is very convenient. "
United States
Sherlene
The price is S$201
includes taxes & fees
12 Jan - 13 Jan
Holiday Inn Express San Diego Airport - Old Town by IHG

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.4 km from Serra Mesa
8.6 out of 10, Excellent, (1344)
"Clean room, Good breakfast and close to all attractions"
United States
SRIVANI
The price is S$136
includes taxes & fees
27 Jan - 28 Jan
Hampton Inn San Diego/Mission Valley

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1472)
"I loved my stay here"
United States
José
The Bristol Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 36 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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