Serra Mesa

San Diego

A residential area with houses, roads, and a hilly landscape.

Stay near popular Serra Mesa attractions

Civita Dog Park

After visiting Civita Dog Park, make a plan to see the other sights and activities in San Diego.
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Things to do

San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

S$72
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego City Lights Night Tour

San Diego City Lights Night Tour

S$56
per adult
96% of travellers recommend
San Diego City Lights Night Tour
San Diego Whale Watching Cruise

San Diego Whale Watching Cruise

S$110
per adult
92% of travellers recommend
San Diego Whale Watching Cruise
San Diego Premier Bottomless Mimosa Brunch Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

S$137
per adult
90% of travellers recommend
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

S$157
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
Champagne Sunday Brunch Cruise

Champagne Brunch Buffet

S$160
per adult
92% of travellers recommend
Champagne Brunch Buffet
See all activities in San Diego

Top hotels in Serra Mesa

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
The price is S$363 per night from 7 Sept to 8 Sept
S$363
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (2,823 reviews)
"During our stay, the air conditioning quit working. The staff made arrangements for us to change rooms and took great care of us."

Reviewed on 31 Aug, 2026

Manchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is S$372 per night from 7 Sept to 8 Sept
S$372
7 Sept - 8 Sept
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,849 reviews)
"Room was clean and neat. Staff was very helpful. Pools and ground were awesome. A great stay!"

Reviewed on 30 Aug, 2026

Paradise Point Resort & Spa
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
The price is S$117 per night from 1 Sept to 2 Sept
S$117
1 Sept - 2 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (2,907 reviews)
"Everything went well check in and out. Thanks staff"

Reviewed on 31 Aug, 2026

California Suites Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is S$269 per night from 3 Sept to 4 Sept
S$269
3 Sept - 4 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,320 reviews)
"Enjoyed my stay very much. Very helpful staff and clean. Great views on the Bayfront."

Reviewed on 31 Aug, 2026

Wyndham San Diego Bayside
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
The price is S$272 per night from 1 Sept to 2 Sept
S$272
1 Sept - 2 Sept
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
9/10 Wonderful! (4,443 reviews)
"good"

Reviewed on 31 Aug, 2026

The Dana on Mission Bay
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is S$323 per night from 1 Sept to 2 Sept
S$323
1 Sept - 2 Sept
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (4,268 reviews)
"Great location. Walking distance from Petco Park."

Reviewed on 31 Aug, 2026

Hard Rock Hotel San Diego
See all 9,255 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.
A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

A beach with surfers and swimmers during sunset.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Serra Mesa