Serra Mesa
San Diego
Visit Serra Mesa
Popular places to visit

San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.

Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.

Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.

SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Things to do

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Whale Watching Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

San Diego City Lights Night Tour

City Cruises San Diego: Premier Dinner Cruise
Top hotels in Serra Mesa

Wyndham San Diego Bayside
Reviewed on 1 Oct, 2025

Manchester Grand Hyatt San Diego
Reviewed on 30 Sept, 2025

The DEXTRO Little Italy, BW Premier Collection
Reviewed on 1 Oct, 2025

DoubleTree by Hilton San Diego - Del Mar
Reviewed on 30 Sept, 2025

Handlery Hotel
Reviewed on 1 Oct, 2025

The Dana on Mission Bay
Reviewed on 28 Sept, 2025
Other neighbourhoods around Serra Mesa

Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Fashion Valley Mall and Snapdragon Stadium, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Del Cerro
While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Old Town San Diego
The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.