Serra Mesa
San Diego
Visit Serra Mesa
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Whale Watching Cruise
San Diego City Lights Night Tour
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
Top hotels in Serra Mesa
Sheraton San Diego Resort
The room was clean, the staff was great. We left for the day and forgot to remove the "privacy" sign. We didn't get clean towels and our dirty ones were on the floor. It was totally our fault that we didn't get clean towels. I requested some and they were very understanding and very prompt at getting ...
Reviewed on 1 Jan, 2026
Bay Club Hotel & Marina
Staff are very friendly. Daily room service is great! Marina view from room and lobby are amazing.only thing is facility is a bit old, especially bathroom tub and toilet are outdated. And it has a bit smell of mold in bathroom
Reviewed on 27 Dec, 2025
The DEXTRO Little Italy, BW Premier Collection
Good breakfast for 20 bucks.
Reviewed on 30 Dec, 2025
Courtyard by Marriott San Diego Downtown Little Italy
Excellent
Reviewed on 27 Dec, 2025
Legacy Resort Hotel & Spa
The rooms were spotless and quiet! We had a beautiful view from our balcony. Kassie was a wonderful hostess when we arrived to the end when we checked out. We will definitely be staying here again in the future. Thank you Kassie you were so kind and generous to our family. You are a great young ...
Reviewed on 27 Dec, 2025
San Diego Marriott La Jolla
clean, friendly, accommodating
Reviewed on 31 Dec, 2025
Other neighbourhoods around Serra Mesa
Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Del Cerro
While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.
Old Town San Diego
The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
