Hotels in Serra Mesa

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Our top choices for Serra Mesa hotels

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1271)
"Locations is excellent and the front desk lady was friendly "
Canada
Ju
Urban Boutique Hotel

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1018)
"Great hotel, excellent location, excellent view on rooftop!"
United States
Rajeev
The price is S$158
includes taxes & fees
7 Jan - 8 Jan
Gaslamp Plaza Suites

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1903)
"Great location! "
United States
Kristin
La Pensione Hotel

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1903)
"The staff was very nice and great location"
United States
Curtis
The price is S$124
includes taxes & fees
11 Jan - 12 Jan
GreenTree Inn San Diego Mission Bay

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1198)
"The room was nice"
United States
Charlotte
The price is S$92
includes taxes & fees
7 Jan - 8 Jan
Heritage Inn San Diego

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
9.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1009)
"Staff were great, location was convenient, comfortable bed and clean room. One complaint - the shower water wasn’t hot. "
United States
Hannah
The price is S$194
includes taxes & fees
14 Jan - 15 Jan
Best Western Plus Bayside Inn

SureStay Hotel by Best Western San Diego Pacific Beach

SureStay Hotel by Best Western San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1463)
"Clean room , good breakfast, convenient location "
United States
Angela
The price is S$92
includes taxes & fees
13 Jan - 14 Jan
SureStay Hotel by Best Western San Diego Pacific Beach

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4144)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is S$125
includes taxes & fees
12 Jan - 13 Jan
Wyndham Garden San Diego Near SeaWorld

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
9.6 km from Serra Mesa
8.2 out of 10, Very good, (2336)
"Nice and convenient place to stay!"
United States
Esperanza
The price is S$156
includes taxes & fees
21 Jan - 22 Jan
Hampton Inn San Diego-Downtown

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3226)
"Great location, friendly staff 👍 "
United States
Maria
The price is S$125
includes taxes & fees
13 Jan - 14 Jan
Comfort Inn Sea World Area

Springhill Suites San Diego Mission Valley

Springhill Suites San Diego Mission Valley
3.5 star property
3.4 km from Serra Mesa
9.2 out of 10, Wonderful, (1000)
"Clean, convenient, great property "
United States
Dana
The price is S$205
includes taxes & fees
7 Jan - 8 Jan
Springhill Suites San Diego Mission Valley

The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
Marina District, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (2722)
"We stay in this hotel several times throughout the year. Staff is always friendly and rooms are spotless. "
United States
Tianna
The Horton Grand, Downtown/Gaslamp Quarter

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1680)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel

The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar
3.0 star property
Gaslamp Quarter, 9.9 km from Serra Mesa
8.8 out of 10, Excellent, (570)
"A very nice spot to stay in the gas lamp district. "
United States
Janet
The price is S$187
includes taxes & fees
7 Jan - 8 Jan
The Beau Downtown San Diego Gaslamp Quar

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
12.2 km from Serra Mesa
8.6 out of 10, Excellent, (1014)
"Room was spotless, great location."
United States
Dennis
Sea Harbor Hotel

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1477)
"Very nice staff and clean rooms"
United States
Desserae
The Bristol Hotel San Diego

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
11.9 km from Serra Mesa
7.8 out of 10, Good, (1233)
"Cute place... prime location... very clean and updated rooms... comfortable beds. "
United States
Kristin
The price is S$132
includes taxes & fees
13 Jan - 14 Jan
Comfort Inn San Diego Airport At The Harbor

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
North Pacific Beach, 7.4 km from Serra Mesa
8.0 out of 10, Very good, (1442)
"Hotel looks "
United States
Harbhanu
The price is S$136
includes taxes & fees
8 Jan - 9 Jan
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
11.8 km from Serra Mesa
8.6 out of 10, Excellent, (1667)
"Spotless room, nice staff, great breakfast"
United States
DAVID
The price is S$124
includes taxes & fees
7 Jan - 8 Jan
Best Western Yacht Harbor Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1000)
"An excellent stay in an excellent area! Super clean and staff is very nice."
Canada
Emily
The price is S$191
includes taxes & fees
28 Jan - 29 Jan
Staypineapple, Hotel Z, Gaslamp San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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