Hotels in Serra Mesa

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Top 10 Hotels in Serra Mesa

Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3088)
"Our stay was great! Would stay here again"
United States
Carla
The price is S$442
includes taxes & fees
22 Nov - 23 Nov
Hard Rock Hotel San Diego
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6039)
"I enjoyed my stay."
United States
Kevin
The price is S$243
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside
Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3420)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is S$167
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Marina Gateway Hotel
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1213)
"Very friendly staff!"
United States
Glenn
The price is S$192
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 10.1 km from Serra Mesa
8.6 out of 10, Excellent, (2039)
"staff was very friendly and hotel was clean"
United States
Stephany
The price is S$154
includes taxes & fees
22 Nov - 23 Nov
Palihotel San Diego Gaslamp Quarter
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (2658)
"Beautiful and historic, very comfortable. Would definitely stay there again. "
United States
Amy
The Horton Grand, Downtown/Gaslamp Quarter
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
5.7 km from Serra Mesa
9.2 out of 10, Wonderful, (2952)
"Great stay"
United States
Songkwon
The price is S$269
includes taxes & fees
10 Dec - 11 Dec
Legacy Resort Hotel & Spa
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1005)
"Great room, clean, spacious and quiet. "
United States
Maria
The price is S$147
includes taxes & fees
23 Nov - 24 Nov
Gaslamp Plaza Suites
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1428)
"Great stay, clean room. Staff was very friendly as well. Would stay again. "
United States
Alexis
The price is S$169
includes taxes & fees
21 Dec - 22 Dec
The Bristol Hotel San Diego
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
10 km from Serra Mesa
8.4 out of 10, Very good, (1630)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel
Living room
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (848)
"Lovely hotel. Really enjoyed the complimentary bottle of wine as well as how convenient it was to walk to restaurants & bars . "
United States
Gisselle
The price is S$222
includes taxes & fees
23 Nov - 24 Nov
Alma San Diego Downtown, a Tribute Portfolio Hotel
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
10.7 km from Serra Mesa
9.2 out of 10, Wonderful, (1922)
"Great hotel"
United States
Farzana
The price is S$309
includes taxes & fees
28 Nov - 29 Nov
Marriott Marquis San Diego Marina
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1001)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is S$206
includes taxes & fees
24 Nov - 25 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
5.4 km from Serra Mesa
8.0 out of 10, Very good, (2392)
"The room was excellent and the front desk staff very professional."
United States
Nelson
The price is S$133
includes taxes & fees
24 Nov - 25 Nov
Days Inn by Wyndham San Diego Hotel Circle
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

3.5 star property
Mission Bay, 10.1 km from Serra Mesa
8.8 out of 10, Excellent, (3874)
"Overall, nice place to stay!"
United States
Jazmine
The price is S$265
includes taxes & fees
23 Nov - 24 Nov
The Dana on Mission Bay
Exterior
La Pensione Hotel

La Pensione Hotel

3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1908)
"Friendly staff, very nice room, great location!"
United States
Lisa
La Pensione Hotel
Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
9.3 km from Serra Mesa
8.8 out of 10, Excellent, (665)
"Great staff, great location, great value. "
United States
Juan
The price is S$136
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection
Check-in/check-out kiosk
Urban Boutique Hotel

Urban Boutique Hotel

3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1279)
"Alwsys clean , great staff andvperfect location"
United States
Colleen
Urban Boutique Hotel
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
12.6 km from Serra Mesa
9.2 out of 10, Wonderful, (3128)
"Great staff and beautiful location. "
United States
elaine
The price is S$174
includes taxes & fees
23 Nov - 24 Nov
Bay Club Hotel & Marina
3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

4.0 star property
29.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1613)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
Sycuan Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring street scenes, signage and a bar

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park which includes a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

10/10 Excellent
"Really clean"
Lawrence 1-night trip
Posted 1 day ago
Hampton Inn & Suites by Hilton San Diego SeaWorld

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Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.