Hotels in Serra Mesa
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Serra Mesa hotels
Wyndham San Diego Bayside
Wyndham San Diego Bayside9.9 km from Serra Mesa
8.4 out of 10, Very good, (5,994 reviews)
"Perfect location for cruise"
blasimar
The price is S$247
includes taxes & fees
18 Jan - 19 Jan
The Bristol Hotel San Diego
The Bristol Hotel San Diego9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1,468 reviews)
"Clean room, staff was pleasant "
Miguel
The price is S$560
includes taxes & fees
9 Feb - 10 Feb
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 7.2 km from Serra Mesa
8.4 out of 10, Very good, (1,335 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
Dani
The price is S$294
includes taxes & fees
2 Feb - 3 Feb
Paradise Point Resort & Spa
Paradise Point Resort & SpaMission Bay, 9.9 km from Serra Mesa
8.6 out of 10, Excellent, (2,364 reviews)
"Great facility and amenities. We look forward to taking our family back again. "
Andy
The price is S$248
includes taxes & fees
19 Jan - 20 Jan
Sycuan Casino Resort
Sycuan Casino Resort28.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,668 reviews)
"Very clean resort. "
Petrina
Loews Coronado Bay Resort
Loews Coronado Bay Resort19.1 km from Serra Mesa
8.8 out of 10, Excellent, (1,060 reviews)
"The staff and amenities were spectacular. "
Andrew
The price is S$333
includes taxes & fees
8 Feb - 9 Feb
Hard Rock Hotel San Diego
Hard Rock Hotel San DiegoGaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3,222 reviews)
"Great view easy checking in fun atmosphere and good food "
Sergio
The price is S$378
includes taxes & fees
16 Jan - 17 Jan
The Dana on Mission Bay
The Dana on Mission BayMission Bay, 10.1 km from Serra Mesa
9.0 out of 10, Wonderful, (3,987 reviews)
"We had a wonderful stay!"
Megan
The price is S$265
includes taxes & fees
18 Jan - 19 Jan
The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection9.3 km from Serra Mesa
9.0 out of 10, Wonderful, (905 reviews)
"Great stay. Would definitely stay again."
Zoraima
The price is S$165
includes taxes & fees
22 Jan - 23 Jan
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San DiegoMarina District, 10.7 km from Serra Mesa
9.0 out of 10, Wonderful, (2,880 reviews)
"Excellent stay...wonderful staff"
Michelle
The price is S$367
includes taxes & fees
22 Jan - 23 Jan
Humphreys Half Moon Inn
Humphreys Half Moon Inn12.3 km from Serra Mesa
9.2 out of 10, Wonderful, (2,736 reviews)
"Great stay, highly recommend."
Ryan
The price is S$254
includes taxes & fees
2 Feb - 3 Feb
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp QuarterGaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,244 reviews)
"Friendly staff, great location, excellent value overall "
Maryann
The price is S$238
includes taxes & fees
18 Jan - 19 Jan
GreenTree Inn San Diego Mission Bay
GreenTree Inn San Diego Mission BayPacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,901 reviews)
"The staff was very nice and great location"
Curtis
The price is S$108
includes taxes & fees
25 Jan - 26 Jan
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay DowntownMarina District, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,575 reviews)
"Very easy vacation, convenient breakfast as well as location."
Kathy
The price is S$329
includes taxes & fees
30 Jan - 31 Jan
Hampton Inn San Diego/Mission Valley
Hampton Inn San Diego/Mission Valley6.4 km from Serra Mesa
8.6 out of 10, Excellent, (1,363 reviews)
"Great breakfast-comfortable rooms-helpful staff-great location for events"
bill
The price is S$143
includes taxes & fees
25 Jan - 26 Jan
The Sofia Hotel
The Sofia Hotel10 km from Serra Mesa
8.6 out of 10, Excellent, (1,686 reviews)
"Great location and history to the hotel "
Stephanie
DoubleTree by Hilton San Diego - Del Mar
DoubleTree by Hilton San Diego - Del MarCarmel Valley, 17.4 km from Serra Mesa
8.4 out of 10, Very good, (1,971 reviews)
"We had a great stay. The room was clean, the staff friendly and helpful, and the breakfast was excellent."
Christine
The price is S$190
includes taxes & fees
2 Feb - 3 Feb
Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp QuarterGaslamp Quarter, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (1,198 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
Ginger
The price is S$343
includes taxes & fees
30 Jan - 31 Jan
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld9 km from Serra Mesa
7.4 out of 10, Good, (4,135 reviews)
"Get location to the airport, safe, great staff, & overall wonderful stay"
Tyler
The price is S$125
includes taxes & fees
26 Jan - 27 Jan
Best Western Seven Seas
Best Western Seven Seas5.3 km from Serra Mesa
8.0 out of 10, Very good, (3,124 reviews)
"Breakfast was good and the staff was friendly and excellent. "
Thuan
The price is S$104
includes taxes & fees
19 Jan - 20 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Serra Mesa
Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Ocean Beach
With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Belmont Park
- Apartments in Central San Diego
- Hotels with free airport shuttle in Central San Diego
- Clairemont Hotels
- Downtown San Diego Hotels
- Hotels near Fashion Valley Mall
- Gaslamp Quarter Hotels
- Golden Hill Hotels
- Extended Stay America Hotels in Hillcrest
- Hotels near Hotel Circle
- Kearny Mesa Hotels
- La Jolla Village Hotels
- La Mesa Hotels
- Liberty Station Hotels
- Linda Vista Hotels
- Little Italy Hotels
- Miramar Hotels
- Hotels near Mission Basilica San Diego de Alcala
- Hotels near Mission Beach
- Romantic Hotels in Mission Valley
- Mission Valley Hotels
- North Park Hotels
- Old Town San Diego Hotels
- Hotels near Old Town San Diego State Park
- Pacific Beach Hotels
- Hotels near Qualcomm Stadium Station
- Hotels near Red Spade Theater
- Hotels near San Diego Convention Center
- San Diego Hotels
- Hotels near San Diego State University
- Scripps Ranch Hotels
- Sherman Heights Hotels
- Sorrento Valley Hotels
- Hotels near University of San Diego
- Flights from Montgomery Field
- Delta Las Vegas (LAS) to San Diego (SAN) flights
- Klm Amsterdam (AMS) to San Diego (SAN) flights
- Qatar Airways Chennai (MAA) to San Diego (SAN) flights
- Flights from Tucson (AVW) to San Diego (MYF)
- Flights from Bellingham (BLI) to San Diego (SAN)
- Flights from Ceduna (CED) to San Diego (SAN)
- Flights from Chicago (CHI) to San Diego (MYF)
- Flights from Carlsbad (CNM) to San Diego (SAN)
- Flights from Cottonwood (CTW) to San Diego (MYF)
- Flights from Mosinee (CWA) to San Diego (SAN)
- Flights from Calexico (CXL) to San Diego (MYF)
- Flights from Barstow (DAG) to San Diego (MYF)
- Flights from Dallas (DFW) to San Diego (MYF)
- Flights from Denpasar (DPS) to San Diego (SAN)
- Flights from Florence (FLO) to San Diego (SAN)
- Flights from Frankfurt (FRA) to San Diego (MYF)
- Flights from Grand Rapids (GRR) to San Diego (MYF)
- Flights from Hamburg (HAM) to San Diego (MYF)
- Flights from Lake Havasu City (HII) to San Diego (MYF)
- Flights from Tokyo (HND) to San Diego (SAN)
- Flights from Honolulu (HNL) to San Diego (SAN)
- Flights from Huntington (HTS) to San Diego (SAN)
- Flights from El Centro (IPL) to San Diego (MYF)
- Flights from Inyokern (IYK) to San Diego (MYF)
- Flights from Kalamata (KLX) to San Diego (SAN)
- Flights from Los Angeles (LAX) to San Diego (MYF)
- Flights from Manila (MNL) to San Diego (SAN)
- Flights from Marysville (MYV) to San Diego (MYF)
- Flights from Neuquén (NQN) to San Diego (MYF)
- Flights from New York (NYC) to San Diego (SAN)
- Flights from Oaxaca Intl. (OAX) to San Diego (MYF)
- Flights from Oak Harbor (ODW) to San Diego (SAN)
- Flights from Okinoerabu (OKE) to San Diego (SAN)
- Flights from North Bend (OTH) to San Diego (SAN)
- Flights from Paraburdoo (PBO) to San Diego (SAN)
- Flights from Setif (QSF) to San Diego (MYF)
- Flights from Murrieta (RBK) to San Diego (MYF)
- Flights from Raleigh (RDU) to San Diego (MYF)
- Flights from Sao Paulo (SAO) to San Diego (MYF)
- Flights from San Bernardino (SBD) to San Diego (MYF)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from Singapore (SIN) to San Diego (SAN)
- Flights from Sion (SIR) to San Diego (SAN)
- Flights from Salt Lake City (SLC) to San Diego (MYF)
- Flights from Stockholm (STO) to San Diego (SAN)
- Flights from Santa Rosa (STS) to San Diego (MYF)
- Flights from Sydney (SYD) to San Diego (MYF)
- Flights from Santa Paula (SZP) to San Diego (MYF)
- Flights from Thermal (TRM) to San Diego (MYF)
- Flights from Ulaanbaatar (ULN) to San Diego (MYF)
- Flights from Las Vegas (VGT) to San Diego (MYF)
- Flights from Willows (WLW) to San Diego (MYF)
- Flights from Watsonville (WVI) to San Diego (MYF)
- Flights from Brandon (YBR) to San Diego (SAN)
- Flights from Peawanuck (YPO) to San Diego (SAN)