Downtown South San Francisco

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is S$145 per night from 31 May to 1 Jun
S$145
31 May - 1 Jun
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,973 reviews)
It was a very enjoyable stay. Very clean, breakfast was okay had a selection of basic foods. We didn't need parking however it looked as if there was plenty of space. The staff was Super friendly, helpful and went above what was expected. Thank You All!

Reviewed on 8 May, 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is S$269 per night from 25 May to 26 May
S$269
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,469 reviews)
Overall the hotel was great. The staff are amazing and helpful. The breakfast is a buffet and has a variety of options. Pool is nice as well but too cold during this time. The rooms were clean tidy and decently spacious. Only issue is the wifi isn’t the greatest and at times slow.

Reviewed on 8 May, 2026

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is S$197 per night from 25 May to 26 May
S$197
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,709 reviews)
Easy check in, walkable distance to everywhere, clean environment

Reviewed on 8 May, 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is S$238 per night from 25 May to 26 May
S$238
25 May - 26 May
includes taxes & fees
Stay at this family-friendly hotel in San Francisco. Enjoy free Wi-Fi, a fitness centre and valet parking (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (3,104 reviews)
Stayed in the older part of the hotel. What I liked best was that the windows open, so you can cool the room down and have fresh air at night. The room was a decent size. Mini fridge in the room and a water bottle filling station down the hall. The front desk staff were not the most welcoming, but ...

Reviewed on 8 May, 2026

Handlery Union Square Hotel
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
The price is S$189 per night from 28 May to 29 May
S$189
28 May - 29 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (3,121 reviews)
The air conditioning did not work. The front desk said someone would fix it. I came back in the evening and it was never fixed. The room is clean. The bathrooms are motel-esque. And the rooms are small. The water refill station was questionable. The water had a very poor taste and the system is inefficient. ...

Reviewed on 8 May, 2026

Club Quarters Hotel in San Francisco
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is S$386 per night from 25 May to 26 May
S$386
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,219 reviews)
So, there are three Hyatt's in San Francisco. My reservation was for the Hyatt Regency San Francisco, at Embarcadero Center. There is also a Hyatt Regency San Francisco Airport, and Hyatt SOMA. I asked if there was a hotel shuttle from the airport, for Hyatt Regency San Francisco, and was told yes. ...

Reviewed on 6 May, 2026

Hyatt Regency San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. San Francisco Public Library is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Potrero Hill

Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Museum of Craft & Design are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
Sunset District

Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
South of Market

South of Market

3.5/5(115 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

South of Market
 Japanese Tea Garden in Golden Gate Park reflecting in one of the koi ponds. San Fancisci, California

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate


Downtown South San Francisco