Hotels in Downtown South San Francisco

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6 Oct - 7 Oct
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Top 10 Hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Exterior

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very good, (2010)
"Great place to stay "
The price is S$153
includes taxes & fees
26 Oct - 27 Oct
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Airport Inn
Interior detail

Airport Inn

2.0 star property
8.8 out of 10, Excellent, (962)
"I was surprised by how friendly the front desk guy was when I checked in after midnight, and also by how clean the room was, for the price I would say this is unbeatable for the area, I will be back."
The price is S$143
includes taxes & fees
12 Oct - 13 Oct
Airport Inn
Inn By The SFO
Lobby

Inn By The SFO

2.0 star property
7.8 out of 10, Good, (1001)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
Inn By The SFO
Miller Apartments
Fridge, microwave, coffee/tea maker, dining tables

Miller Apartments

2.0 star property
7.8 out of 10, Good, (14)
"Ty"
The price is S$192
includes taxes & fees
11 Oct - 12 Oct
Miller Apartments
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Free daily buffet breakfast

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
9.0 out of 10, Wonderful, (2158)
"Had a wonderful stay, staff was wonderful."
The price is S$254
includes taxes & fees
5 Nov - 6 Nov
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Harbor View Inn
Premium bedding, down duvets, in-room safe, desk

Harbor View Inn

2.0 star property
9.0 out of 10, Wonderful, (581)
"Easy parking, friendly staff, coffee and sodas available 24 hrs"
Harbor View Inn
Hotel North Beach
Lobby

Hotel North Beach

2.0 star property
7.0 out of 10, Good, (1008)
"Shops great food cool vibe this the coolest place love it "
Hotel North Beach
Half Moon Bay Lodge
Exterior

Half Moon Bay Lodge

3.0 star property
9.0 out of 10, Wonderful, (1007)
"Definitely would stay there again. Felt like being with family."
The price is S$254
includes taxes & fees
4 Nov - 5 Nov
Half Moon Bay Lodge
Hotel Caza Fisherman's Wharf
Exterior

Hotel Caza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (3798)
"very nice place to stay"
The price is S$250
includes taxes & fees
4 Nov - 5 Nov
Hotel Caza Fisherman's Wharf
The Lodge at Tiburon
Front of property

The Lodge at Tiburon

3.5 star property
8.8 out of 10, Excellent, (1000)
"Overall a great stay. "
The price is S$330
includes taxes & fees
2 Nov - 3 Nov
The Lodge at Tiburon
The Marina Inn on San Francisco Bay
Outdoor pool

The Marina Inn on San Francisco Bay

2.5 star property
8.6 out of 10, Excellent, (2124)
"Great value, convenient location, & the staff was very nice. "
The Marina Inn on San Francisco Bay
FOUND Hotel Carlton, Nob Hill
Front of property

FOUND Hotel Carlton, Nob Hill

2.0 star property
8.6 out of 10, Excellent, (933)
"Great staff- great locations"
The price is S$100
includes taxes & fees
3 Nov - 4 Nov
FOUND Hotel Carlton, Nob Hill
Hyatt Centric Fisherman's Wharf San Francisco
Terrace/patio

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
8.6 out of 10, Excellent, (1419)
"Great place to stay."
The price is S$258
includes taxes & fees
2 Nov - 3 Nov
Hyatt Centric Fisherman's Wharf San Francisco
Hotel Riu Plaza Fisherman's Wharf
Lobby sitting area

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6934)
"Very clean, wonderful staff, amazing breakfast, and close to all fishermen’s Wharf activities!!"
The price is S$253
includes taxes & fees
5 Nov - 6 Nov
Hotel Riu Plaza Fisherman's Wharf
Hotel Majestic
Front of property

Hotel Majestic

3.5 star property
9.2 out of 10, Wonderful, (1011)
"I love how close the hotel is to Japan Town, this is our second time staying there and will be back for a third stay in the near future!"
The price is S$224
includes taxes & fees
19 Oct - 20 Oct
Hotel Majestic
HYATT house Emeryville/San Francisco Bay Area
Exterior

HYATT house Emeryville/San Francisco Bay Area

3.0 star property
9.0 out of 10, Wonderful, (1137)
"The hotel experience was great. We will definitely be staying in there again."
The price is S$220
includes taxes & fees
19 Oct - 20 Oct
HYATT house Emeryville/San Francisco Bay Area
Hotel Skye SFO
In-room safe, desk, laptop workspace, iron/ironing board

Hotel Skye SFO

3.0 star property
8.8 out of 10, Excellent, (1454)
"We enjoyed the stay"
The price is S$166
includes taxes & fees
2 Nov - 3 Nov
Hotel Skye SFO
Hyatt Regency San Francisco Airport
Exterior

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1320)
"The location was great"
The price is S$231
includes taxes & fees
2 Nov - 3 Nov
Hyatt Regency San Francisco Airport
SFO El Rancho Inn SureStay Collection by Best Western
Exterior

SFO El Rancho Inn SureStay Collection by Best Western

3.0 star property
8.4 out of 10, Very good, (2858)
"Ideal for a stopover night."
The price is S$189
includes taxes & fees
19 Oct - 20 Oct
SFO El Rancho Inn SureStay Collection by Best Western
The Dylan at SFO
Lobby sitting area

The Dylan at SFO

3.0 star property
9.2 out of 10, Wonderful, (1761)
"Nice place to stay "
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.
Union Square showing a city and a skyscraper

Union Square

Fashion puts its best foot forward in this vast shopping plaza.

Fisherman’s Wharf which includes a bay or harbour

Fisherman's Wharf

Dating back to the middle of the 19th Century, this historic wharf has been through many incarnations. Today it’s bursting with fun, sea lions and restaurants.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market which includes a city, a park and skyline

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing a city and street scenes

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

10/10 Excellent
"When staying here for 2 nights in September 2025, I was very satisfied. Clean rooms, friendly and helpful staff. I then left for an overseas trip and had scheduled to stay at Bay Landing again on the way back for one night. The second stay was not so pleasant. Was given a room, that looked very tired. Faucet in bathtub was loose, air conditioning unit had a little fabric blowing in the breeze. Refrigerator had no freezing compartment, when asked, the front desk person would not freeze the freezer pack. This has been done in the past with other accommodations without a problem, both stateside and overseas. So, my suggestion is that Bayside either change their policy for diabetics, or find another hotel more accommodating. "
Astrid 2-night trip
Posted 2 days ago
Bay Landing San Francisco Airport Hotel

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Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.

What's a favourite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favourite options in the area include Airport Inn and Inn By The SFO.

How many hotels should I expect to find in the Downtown South San Francisco area?

When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.

What can I see and do in this South San Francisco neighbourhood?

See's Candies, Cinemark Century at Tanforan and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.