S$341 Cheap Flights from Panama City to San Francisco

View S$341 flight on Tue, 26 Aug, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Panama City to San Francisco (PTY-SFO)

Prices were available within the past 7 days and start at S$341 for one-way flights and S$839 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$839 Return, found 10 hours ago
S$839
Return
found 10 hours ago
Select Copa flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$839 found 10 hours ago
avianca
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$884 Return, found 10 hours ago
S$884
Return
found 10 hours ago
Select avianca flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$884 found 10 hours ago
avianca
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$889 Return, found 10 hours ago
S$889
Return
found 10 hours ago
Select avianca flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$889 found 10 hours ago
United
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$896 Return, found 10 hours ago
S$896
Return
found 10 hours ago
Select United flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$896 found 10 hours ago
United
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$903 Return, found 10 hours ago
S$903
Return
found 10 hours ago
Select United flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$903 found 10 hours ago
avianca
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$936 Return, found 10 hours ago
S$936
Return
found 10 hours ago
Select avianca flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$936 found 10 hours ago
avianca
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$938 Return, found 10 hours ago
S$938
Return
found 10 hours ago
Select avianca flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$938 found 10 hours ago
avianca
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$942 Return, found 10 hours ago
S$942
Return
found 10 hours ago
Select avianca flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$942 found 10 hours ago
American Airlines
Fri, 25 Jul - Tue, 29 Jul
PTY
Panama City
SFO
San Francisco
S$1,132 Return, found 10 hours ago
S$1,132
Return
found 10 hours ago
Select American Airlines flight, departing Fri, 25 Jul from Panama City to San Francisco, returning Tue, 29 Jul, priced at S$1,132 found 10 hours ago
Delta
Sat, 12 Jul - Wed, 16 Jul
PTY
Panama City
SFO
San Francisco
S$2,001 Return, found 4 hours ago
S$2,001
Return
found 4 hours ago
Select Delta flight, departing Sat, 12 Jul from Panama City to San Francisco, returning Wed, 16 Jul, priced at S$2,001 found 4 hours ago

Find the cheapest month to fly from Panama City (PTY) to San Francisco (SFO)

August is typically the cheapest month to fly

From S$601 - S$1,074 per traveller.

Graph displaying average flight prices per month

Panama City to San Francisco route information
Origin airport
Tocumen Intl.
Destination airport
San Francisco Intl.
Return price
S$839
Distance
5313 km
Average flight time
5 hours 45 mins

Flights from Tocumen to San Francisco

There are several airlines that operate frequent flights from Panama (PTY) to San Francisco (SFO) including

The earliest flight leaves Tocumen Intl. Airport at 09:23 and arrives at San Francisco Intl. Airport at 00:08. The last flight of the day departs Panama at 18:31 and arrives at San Francisco at 23:08.

The flight distance from Panama to San Francisco is about 5372 km, the shortest flight is 07 hours 31 minutes with United Airlines.

Expedia lets you search across the largest number of airlines and San Francisco flights, which means that you’ll be able to find a great flight deal at the perfect travel date and time. Our simple-to-use booking engine makes looking for terrific bargains easy and hassle-free; just enter your travel dates and departure city, and let Expedia do the rest! Adjust your travel dates and explore connecting flights to find an even better deal on your Tocumen San Francisco flight!

Browse through dozens of options and rest assured that you’re seeing the best price guaranteed! Our friendly customer service representatives are here to serve you 24 hours day to provide assistance and answer any questions that you may have about booking your Tocumen to San Francisco trip. There’s simply no substitute for great prices suited to your travel needs and backed by excellent customer support.

Combine your San Francisco flight with a hotel and/or car rental for a package deal designed to save you even more money! Discover additional savings by booking in advance or find a last minute deal. There are tons of ways to save on your flights from Tocumen to San Francisco with Expedia. Use us as your stop travel destination and have the confidence that you’re getting a bargain!

Frequently asked questions

How much is a flight from PTY to San Francisco Intl. Airport (SFO)?
Based on fares offered within the last 7 days on Expedia for flights departing within the next year, round-trip journeys from PTY to San Francisco Intl. Airport (SFO) start from S$839. Make your booking ASAP to get the best price for your adventure. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Tocumen Intl. Airport (PTY) to San Francisco Airport?
We understand that things crop up unexpectedly, so we've made it as hassle-free as possible for you to cancel your flight online. Just head to the Customer Service Portal and follow the instructions.
How do I find cheap flights from PTY to San Francisco Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to San Francisco Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Panama Airport to San Francisco Airport?
With around 5,400 kilometres separating Tocumen and San Francisco, your flight will be a long one. Pack wisely to make your trip comfortable. Things like a sleep mask and a quality neck pillow can make all the difference.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO)?
Flying nonstop from PTY to SFO is a breeze with Copa Airlines (CM). This popular carrier operates 30 flights each month.
Are Tocumen Intl. Airport (PTY) to SFO flight tickets cheaper when they're purchased at the last minute?
It is possible to nab great last-minute deals from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO), but there's no guarantee. As many airlines release seats up to 12 months in advance, it's worthwhile keeping an eye on fares early and being ready to book when you spot a bargain. Expedia compares carrier prices and updates flight deals regularly, so you can feel confident knowing you're always seeing the latest offers.

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