S$541 Cheap Flights from Panama City to San Francisco

Based on fares offered within the last 7 days on Expedia for flights departing within the next year, round-trip journeys from PTY to San Francisco Intl. Airport (SFO) start from S$1,003. Make your booking ASAP to get the best price for your adventure. Prices and availability are subject to change. Additional terms apply.

We understand that things crop up unexpectedly, so we've made it as hassle-free as possible for you to cancel your flight online. Just head to the Customer Service Portal and follow the instructions.

Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to San Francisco Airport flights, you'll see a "no change fees" filter for you to select.

With around 5,400 kilometres separating Tocumen and San Francisco, your flight will be a long one. Pack wisely to make your trip comfortable. Things like a sleep mask and a quality neck pillow can make all the difference.

Flying nonstop from PTY to SFO is a breeze with Copa Airlines (CM). This popular carrier operates 30 flights each month.

It is possible to nab great last-minute deals from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO), but there's no guarantee. As many airlines release seats up to 12 months in advance, it's worthwhile keeping an eye on fares early and being ready to book when you spot a bargain. Expedia compares carrier prices and updates flight deals regularly, so you can feel confident knowing you're always seeing the latest offers.