Downtown South San Francisco
San Francisco
Visit Downtown South San Francisco
Things to do
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
California Academy of Sciences Daytime Admission
San Francisco: One day Yosemite and Giant Sequoias Tour
San Francisco Bay Sunset Cruise by Luxury Catamaran
de Young Museum General Admission Ticket
Exclusive Muir Woods, Napa & Sonoma Full-Day Wine Tour from San Francisco
Top hotels in Downtown South San Francisco
La Quinta Inn & Suites by Wyndham San Francisco Airport N
"The front staff Chris and others are the star of your hotel. There professionalism and excellent quality support and service was above standards. The two young ladies who assisted my checkin on Saturday morning September 19th were by far excellent personnel whom treated their guest with courtesy, ..."
Reviewed on 20 Sept, 2026
Holiday Inn Golden Gateway by IHG
"Good service"
Reviewed on 21 Sept, 2026
Hotel Riu Plaza Fisherman's Wharf
"Very busy. There is a line for everything. Our room had mold around the tub."
Reviewed on 21 Sept, 2026
Handlery Union Square Hotel
Hilton San Francisco Financial District
Chancellor Hotel on Union Square
"Parking was convenient, room was clean, staff was super friendly and attentive. Great location! Thanks Chancellor staff for an awesome stay!!!"
Reviewed on 21 Sept, 2026
Check Downtown South San Francisco hotel availability
Where to stay in Downtown South San Francisco
Fisherman's Wharf
Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.
Union Square
Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.
Downtown San Francisco
Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.
South of Market
Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.
Nob Hill
Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.
