What is Santa Ana like?

Travellers to Cusco's Santa Ana neighbourhood will be sure to enjoy a stay here.

What's a favourite place to stay in Santa Ana?

Based on our traveller data, Hilton Garden Inn Cusco is one of the top choices for your stay in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant.

How many hotels should I expect to find in the Santa Ana area?

If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 47 Santa Ana hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view top deals in Santa Ana.

What can I see and do in this Cusco neighbourhood?

A few places to visit in the area around Santa Ana include Museo Irq’i Yachay, Museo de Plantas Sagradas Magicas y Medicinales and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.

Top 10 Santa Ana Hotels of 2026

An aerial view of a town nestled in a valley with mountains in the background.

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Our top choices for Santa Ana hotels

A covered outdoor seating area with modern furniture and arches.

1. Hilton Garden Inn Cusco

Santa Ana

alan

20 Nov - 21 Nov

A courtyard with a fountain, outdoor seating, and a staircase leading to an upper level.

2. Tierra Viva Cusco Saphi

Santa Ana

David

21 Nov - 22 Nov

A room with a large arched window overlooking a cityscape.

3. Loki Boutique Cusco

Santa Ana

Jessica

4 Nov - 5 Nov

A hotel room with a large bed, a flat-screen TV, a view of the city, and a wooden floor.

4. Mirador All Sur Cusco

Santa Ana

Veronica Aide

26 Oct - 27 Oct

A spacious lobby with a central staircase, multiple seating areas, and potted plants.

5. Hotel Mamasara

Santa Ana

Barbara A.

A hotel room with a bed, a desk, a TV, and a red chair.

6. Inti Punku Cusco Centro Histórico Hotel

Santa Ana

A room with a view of a cityscape and mountains through a window with a wooden chair in the foreground.

7. Anata Hostel

Santa Ana

christiane

18 Nov - 19 Nov

A modern interior with a staircase, wooden flooring, and colorful arches.

8. Centro by Casa Andina Cusco Saphi

Santa Ana

Michel

21 Nov - 22 Nov

A modern hotel room with two beds, a desk, a chair, a TV, and a wardrobe.

9. ZEVEN HOUSE - CUSCO APARTMENT

Santa Ana

"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...

Andrew

24 Oct - 25 Oct

A spacious room with a large window offering a mountain view, wooden furniture, and a swing chair.

10. Hotel El Mirador de Santa Ana

Santa Ana

Claudia Guadalupe Loya

27 Oct - 28 Oct

A kitchen with a sink, a trash bin, a refrigerator, and various kitchen utensils and appliances.

11. Casa del Valle

Santa Ana

19 Nov - 20 Nov

A hotel room with two beds, a large window, and a ceiling fan.

12. HOSTAL LA RASA

Santa Ana

Alison

17 Nov - 18 Nov

A hotel room with two beds, a window with curtains, a nightstand, and a wall-mounted light.

13. Eco Bunnu Inn Santa Ana

Santa Ana

thais

27 Oct - 28 Oct

A hotel room with two beds, a balcony with a table and chairs, and a view of a building and hills.

14. valicha casa hotel

Santa Ana

HSINNENG

4 Nov - 5 Nov

An outdoor seating area with tables and chairs, a stone archway with colorful decorations, and potted plants.

15. Tucan Hostel

Santa Ana

MERCEDES

20 Nov - 21 Nov

16. JUAN PLACIDO Hospedaje

Santa Ana

20 Nov - 21 Nov

A spacious indoor area with a high ceiling, a staircase, a bench, and several potted plants.

17. Munay Ñusta Cusco

Santa Ana

Arthur

18 Nov - 19 Nov

A compact kitchen with white walls, a refrigerator, a microwave, and a sink.

18. Casa Karmenka

Santa Ana

21 Nov - 22 Nov

A hotel interior with a central atrium, multiple balconies with wrought iron railings, and a skylight.

19. Hotel Hacienda Cusco Centro Historico

Cusco Historic Center, 0.3 km from Santa Ana

Diana

5 Nov - 6 Nov

A courtyard with a red building, a wooden bench, and a hanging plant.

20. Tambo del Arriero Hotel Boutique

Cusco Historic Center, 0.3 km from Santa Ana

Zenab

21 Nov - 22 Nov

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Compare popular hotels in Santa Ana

Property	Property class	Guest rating
Tierra Viva Cusco Saphi	3.0 star property	9.4 Exceptional 510 reviews	View
Centro by Casa Andina Cusco Saphi	3.0 star property	9.4 Exceptional 18 reviews	View
Hotel El Mirador de Santa Ana	2.5 star property	9.2 Wonderful 5 reviews	View
Hotel Mamasara	3.0 star property	8.4 Very good 18 reviews	View
Anata Hostel	3.0 star property	8.4 Very good 32 reviews	View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

A historic cathedral with two bell towers and a large dome.

Cusco Historic Center

Cusco Historic Center is known for its popular shops, and with sights like Santa Catalina Convent and Coricancha, you won't get bored spending a day wandering around this part of Cusco.

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A narrow cobblestone street flanked by white buildings with blue shutters and wrought iron balconies.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

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A cityscape with red-tiled roofs, a prominent church, and distant mountains.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Museo de Arte Precolombino and Plaza Sán Cristobal.

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A person climbing a stone wall with a backpack.

Santiago

If you're spending some time in Santiago, Santiago Plaza and "El Molino I" Shopping Center are top sights worth seeing.

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Terraced fields, mountains, and a clear sky.

Coripata

While Coripata may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Centro Qosqo de Arte Nativo and Coricancha.

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Top Santa Ana Hotel Reviews

Ureta Hotel

10/10 Excellent

"A very nice family hotel. Everybody super friendly. When coming back from a trip the owner comes outside to welcome you back ! Very kids friendly hotel."

Atoq San Blas Hotel

10/10 Excellent

"This was an amazing hotel, clean spacious quiet rooms. The staff was more than just helpful. They were very accommodating and always met us with a smile and a greeting. With warm teeth, Breakfast was great and the staff in the breakfast area were very pleasant. Laundry services were available. Shops were nearby as we were right off the main old town Square. The location was fabulous. We would highly recommend this hotel."

Union Hotel Cusco

8/10 Good

"Staff very helpful and polite. They offer free airport collection and breakfast bags for early pick ups for tours. Location is great, only a short walk to the main square and most tours pick up from hotel. Only issues were the water wasn’t very warm on the first night and having a room that overlooks the courtyard can be very loud at times, especially on days where there is live music and you have an early start the next morning."

Hilton Garden Inn Cusco

10/10 Excellent

"The property was extremely nice and we especially enjoyed the Cocoa Tea and cookies served daily in the lobby. We also loved he beautiful courtyard and seating with easy entry into the bar and the restaurant. We had a lovely young lady named Analia who was so sweet, gracious and helpful! On our last day she saw me struggling to carry two cups of coffee to the courtyard and immediately ran to my rescue! She said, “Mr. Carl, let me help you” and took the cups and walked them gracefully to our table without spilling a drop! She then said anytime I needed to just say Analia, Help and she would be there! Such a ray of sunshine and the Hilton Garden in is so lucky to have such a great ambassador who’s very actions demonstrate the meaning of hospitality!"

Hotels in Santa Ana

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Our top choices for Santa Ana hotels

1. Hilton Garden Inn Cusco

2. Tierra Viva Cusco Saphi

3. Loki Boutique Cusco

4. Mirador All Sur Cusco

5. Hotel Mamasara

6. Inti Punku Cusco Centro Histórico Hotel

7. Anata Hostel

8. Centro by Casa Andina Cusco Saphi

9. ZEVEN HOUSE - CUSCO APARTMENT

10. Hotel El Mirador de Santa Ana

11. Casa del Valle

12. HOSTAL LA RASA

13. Eco Bunnu Inn Santa Ana

14. valicha casa hotel

15. Tucan Hostel

16. JUAN PLACIDO Hospedaje

17. Munay Ñusta Cusco

18. Casa Karmenka

19. Hotel Hacienda Cusco Centro Historico

20. Tambo del Arriero Hotel Boutique

Compare popular hotels in Santa Ana

Where to stay in Santa Ana

Cusco Historic Center

San Blas

San Cristóbal

Santiago

Coripata

Top Santa Ana Hotel Reviews

Ureta Hotel

Frequently asked questions