Photo by Bill Dillard

Southeast Missouri Hotels from from S$72

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southeast Missouri hotels

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1,005 reviews)
"It was a nice stay."
United States
Rebecca
The price is S$79
includes taxes & fees
12 Jan - 13 Jan
Motel 6 Poplar Bluff, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."
United States
Nicole
The price is S$133
includes taxes & fees
15 Jan - 16 Jan
Drury Inn & Suites Sikeston, MO

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (470 reviews)
"Clean room, very nice staff"
United States
Mack
The price is S$118
includes taxes & fees
12 Jan - 13 Jan
The Farmstead Hotel

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (685 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is S$117
includes taxes & fees
13 Jan - 14 Jan
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
"Great place "
United States
Kelly
The price is S$131
includes taxes & fees
19 Jan - 20 Jan
Drury Plaza Hotel Cape Girardeau Conference Center

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (728 reviews)
"Clean room and easy access to room"
United States
Anne
The price is S$81
includes taxes & fees
12 Jan - 13 Jan
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (864 reviews)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
United States
Brenda
The price is S$151
includes taxes & fees
31 Jan - 1 Feb
Fairfield Inn & Suites by Marriott Poplar Bluff

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,008 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is S$99
includes taxes & fees
18 Jan - 19 Jan
Best Western Plus Sikeston

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.4 out of 10, Exceptional, (219 reviews)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
United States
Joanne
The price is S$205
includes taxes & fees
25 Jan - 26 Jan
Echo Bluff State Park

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (711 reviews)
"Amazing place"
United States
Mladen
The price is S$160
includes taxes & fees
16 Jan - 17 Jan
Holiday Inn Poplar Bluff by IHG

Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.4 out of 10, Exceptional, (304 reviews)
"Everything was wonderful- the family that owns this is very kind, and it’s in a beautiful location!"
United States
Nathan
Shepherd Mountain Inn

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,002 reviews)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is S$113
includes taxes & fees
12 Jan - 13 Jan
Drury Inn & Suites Jackson MO

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (977 reviews)
"Great location and room "
United States
Curtis
The price is S$147
includes taxes & fees
15 Jan - 16 Jan
Drury Inn & Suites Poplar Bluff

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (336 reviews)
"Staff was very friendly."
United States
Joyce
The price is S$126
includes taxes & fees
18 Jan - 19 Jan
Honeysuckle Inn - Mountain View

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445 reviews)
"Stay was excellent "
United States
Kourtney
The price is S$136
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (175 reviews)
"Absolutely Love It!!! Clean, Quiet, and all around a safe place to stay..."
United States
Kyle
The price is S$169
includes taxes & fees
12 Jan - 13 Jan
Fort Davidson Hotel

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (462 reviews)
"Very clean and super friendly staff!"
United States
Katherine
The price is S$145
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn Sikeston

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (577 reviews)
"Clean, friendly staff enjoyed the stay"
United States
John
The price is S$189
includes taxes & fees
12 Jan - 13 Jan
Crown Pointe Lodge, BW Signature Collection

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,004 reviews)
"Great stay"
United States
Kelsea Arloetta
The price is S$77
includes taxes & fees
18 Jan - 19 Jan
Baymont Inn and Suites by Wyndham Farmington, MO

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is S$103
includes taxes & fees
15 Jan - 16 Jan
Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:23 Jan - 25 Jan
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Central United States attractions

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star rating