Southeast Missouri Hotels from from S$78

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southeast Missouri hotels

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.4 out of 10, Exceptional, (224 reviews)
"This entire trip was inspired by Tina, a staff member. I met Tina passing through the area and she provided me with a lot of information which gave me the idea to plan a weekend trip with my wife. The lodge room we had was clean and comfortable, My wife and I had a wonderful time exploring most of the areas Tina mentioned. Thank you Tina for a wonderful inspiration for a get away. "
United States
Jared
The price is S$200
includes taxes & fees
26 Feb - 27 Feb
Echo Bluff State Park

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,012 reviews)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is S$107
includes taxes & fees
5 Mar - 6 Mar
Drury Inn & Suites Jackson MO

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (54 reviews)
"I had a great time with my mom there!"
United States
Lily
The price is S$149
includes taxes & fees
26 Feb - 27 Feb
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (512 reviews)
"The room was clean and I was able to check in a bit early."
United States
Sara
The price is S$125
includes taxes & fees
8 Mar - 9 Mar
The Riverview

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (561 reviews)
"Staff was friendly and the place is clean. Our stay was in late January and the air was so very dry and the static electricity from blankets & sheets was off the charts."
United States
Roger
The price is S$144
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express & Suites Perryville by IHG

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (587 reviews)
"Very nice stay. The front desk lady named Tracy was terrific!"
United States
Kevin
The price is S$128
includes taxes & fees
26 Feb - 27 Feb
Crown Pointe Lodge, BW Signature Collection

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (160 reviews)
"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "
United States
Richard
The price is S$133
includes taxes & fees
5 Mar - 6 Mar
Fairfield Inn & Suites by Marriott Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (710 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is S$115
includes taxes & fees
1 Mar - 2 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (996 reviews)
"Great location and room "
United States
Curtis
The price is S$135
includes taxes & fees
1 Mar - 2 Mar
Drury Inn & Suites Poplar Bluff

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (493 reviews)
"Clean room, very nice staff"
United States
Mack
The price is S$99
includes taxes & fees
26 Feb - 27 Feb
The Farmstead Hotel

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
"Great place "
United States
Kelly
The price is S$143
includes taxes & fees
2 Mar - 3 Mar
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
"As always it was a perfect visit"
United States
John
The price is S$137
includes taxes & fees
1 Mar - 2 Mar
Drury Inn & Suites Sikeston, MO

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (113 reviews)
"It was a nice stay"
United States
Douglas
The price is S$141
includes taxes & fees
5 Mar - 6 Mar
Tru By Hilton Cape Girardeau

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (802 reviews)
"Would stay again"
United States
David
The price is S$133
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn Poplar Bluff

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (12 reviews)
"Great stay "
United States
Ashley
The price is S$139
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn By Hilton Dexter

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (338 reviews)
"It was a very nice hassle free stay. I will be staying here again."
United States
Michael Grey
The price is S$124
includes taxes & fees
15 Mar - 16 Mar
Honeysuckle Inn - Mountain View

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (60 reviews)
"Clean rooms great staff"
United States
IRA
The price is S$145
includes taxes & fees
5 Mar - 6 Mar
Fairfield Inn & Suites by Marriott Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (447 reviews)
"Stay was excellent "
United States
Kourtney
The price is S$125
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express & Suites Sikeston Southwest by IHG

Days Inn & Suites By Wyndham Festus

Days Inn & Suites By Wyndham Festus
2.0 star property
Festus
The price is S$137
includes taxes & fees
12 Mar - 13 Mar
Days Inn & Suites By Wyndham Festus

Arcadia Academy

Arcadia Academy
3.0 star property
Arcadia
9.8 out of 10, Exceptional, (11 reviews)
"Love the charm of the room with the hard wood floors, architecture, friendly staff and great food"
United States
Joann
The price is S$187
includes taxes & fees
28 Mar - 29 Mar
Arcadia Academy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.

Holiday Rentals in Southeast Missouri

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Central United States attractions

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star rating