Southeast Missouri Holidays
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Top hotels in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
Reviewed on 10 Sep, 2025
Drury Plaza Hotel Cape Girardeau Conference Center
Reviewed on 10 Sep, 2025
The Riverview
Reviewed on 9 Sep, 2025
Popular places to visit
Lake Wappapello
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
What to do in Southeast Missouri
St Louis: City Museum General Admission Ticket
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
More trip options
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.
