Name: Drury Inn & Suites Sikeston, MO
Price range: S$139
Rating: 9.6

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO

S$145

12 Apr - 13 Apr

includes taxes & fees

Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,005 reviews)

Great stay as always.

Reviewed on 3 Apr, 2026

The Riverview

777 Main St Cape Girardeau MO

S$169

8 Apr - 9 Apr

includes taxes & fees

Stay at this business-friendly hotel in Cape Girardeau. Enjoy free Wi-Fi, free parking and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and ...

9.4/10 Exceptional! (541 reviews)

Clean room. Nice view.

Reviewed on 3 Apr, 2026

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

S$139

9 Apr - 10 Apr

includes taxes & fees

Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

9.6/10 Exceptional! (1,007 reviews)

We decided we will stay here next year on our trip home from Texas.

Reviewed on 3 Apr, 2026

See all 640 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

7555 State Hwy Y French Village MO

Stay at this cabin in French Village. Enjoy free parking, patios and climate control.

9.8/10 Exceptional! (57 reviews)

Beautiful , comfortable!!

Reviewed on 21 Mar, 2026

Johnson's Shut-ins State Park

148 Taum Sauk Trail Middle Brook MO

Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...

10/10 Exceptional! (1 review)

These newer cabins are clean and have everything you need. Highly recommend!

Reviewed on 5 Nov, 2025

Lake Wappapello

8005 Missouri 172 Williamsville MO

Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...

10/10 Exceptional! (1 review)

We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went.

Reviewed on 28 Sept, 2025

See all properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Popular places to visit

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

Current River State Park

Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.