Southeast Missouri

Travel Guide

Southeast Missouri
Southeast Missouri
Southeast Missouri
Photo by Jessica Richter
Photo by Jessica Richter
Photo by Jessica Richter
Photo by Jessica Richter
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
The price is S$81 per night from 1 Sept to 2 Sept
S$81
1 Sept - 2 Sept
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,005 reviews)
"I actually stay there a couple times a month. I do it for the pool most all their staff is very friendly jay is especially/. I would recommend it to anyone."

Reviewed on 17 Aug, 2025

Baymont Inn and Suites by Wyndham Farmington, MO
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
The price is S$153 per night from 20 Aug to 21 Aug
S$153
20 Aug - 21 Aug
includes taxes & fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
9.2/10 Wonderful! (391 reviews)
"It was absolutely wonderful!"

Reviewed on 16 Aug, 2025

The Riverview
The Farmstead Hotel

The Farmstead Hotel

2.5 out of 5
778 E 3rd St, Caruthersville, MO
The price is S$188 per night from 29 Aug to 30 Aug
S$188
29 Aug - 30 Aug
includes taxes & fees
Stay at this hotel in Caruthersville. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (403 reviews)
"My wife and I are very pleased with Homestead Hotel. Very friendly and helpful staff at the front desk. For being 3 years old Homestead Hotel is very clean and welcoming. My wife and I highly recommend this hotel. Another plus with this motel is it’s right next to the casino."

Reviewed on 18 Aug, 2025

The Farmstead Hotel
See all 587 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St. Francois

Postcard Cabins St. Francois

2 out of 5
7555 State Hwy Y, French Village, MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
9.8/10 Exceptional! (27 reviews)
"Our Postcard cabin was a joy. Peaceful, clean, well-stocked, and cool! Could not have been better."

Reviewed on 15 Aug, 2025

Postcard Cabins St. Francois
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.4/10 Exceptional! (148 reviews)
"This is my 3rd time staying here and second time as a family. and every time Ive stayed it has been clean and pleasant. Only a couple run ins with a spider and a wasp. Beyond that we have nothing to complain about and loved the bath!! We will be back again."

Reviewed on 14 Jul, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172, Williamsville, MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
Lake Wappapello
See all properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Elephant Rocks State Park

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Elephant Rocks State Park
Echo Bluff State Park

Echo Bluff State Park

You can take time to visit Echo Bluff State Park during your travels to Salem. While you're in the area, stroll along the riverfront.

Echo Bluff State Park
Rocky Falls

Rocky Falls

Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting.

Rocky Falls
Lake Wappapello

Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

Lake Wappapello

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

Southeast Missouri State University

Century Casino Caruthersville

Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

Century Casino Caruthersville

Things to do

St Louis: City Museum General Admission Ticket

St Louis: City Museum General Admission Ticket

S$29
per adult
96% of travellers recommend
St Louis: City Museum General Admission Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

S$31
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

S$217
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St Louis: 75-Minute City Trolley Tour

St Louis: 75-Minute City Trolley Tour

S$39
per adult
St Louis: 75-Minute City Trolley Tour
Step into the shadows and discover the haunting tales of our city's past.

St. Louis Ghosts: Gateway Ghouls and Hauntings

S$33
per adult
100% of travellers recommend
St. Louis Ghosts: Gateway Ghouls and Hauntings
St Louis Self-Guided Driving and Walking Audio Tour

St Louis Self-Guided Driving and Walking Audio Tour

S$22
per traveller
St Louis Self-Guided Driving and Walking Audio Tour
See all activities in Southeast Missouri