Find Southern Illinois Spa Hotels from S$176

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Southern Illinois Hotels with Spa

Top Hotels with Spa in Southern Illinois

Walker's Bluff Casino Resort
Indoor pool, seasonal outdoor pool

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (343)
"Nice stay"
Walker's Bluff Casino Resort
1895 Washington Hotel
Property entrance

1895 Washington Hotel

3.0 star property
9.0 out of 10, Wonderful, (356)
"James, our host, was very personable and helpful. Hotel had all the modern amenities, but retained its timeless charm. In convenient, quiet location."
1895 Washington Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Staff is phenomenal, and the room was very clean, accommodating all my needs. "
The price is S$176
includes taxes & fees
18 Jul - 19 Jul
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1002)
"5 star experience every time we stay here. The staff is incredible and everything is perfect!"
The price is S$722
includes taxes & fees
22 Jun - 23 Jun
Four Seasons Hotel St Louis
21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1192)
"very nice hotel felt worth the money"
The price is S$234
includes taxes & fees
29 Jun - 30 Jun
21C Museum Hotel St Louis
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (535)
"Great place"
The price is S$868
includes taxes & fees
22 Jun - 23 Jun
The Ritz-Carlton, St. Louis
Ameristar Casino Resort and Spa
6 restaurants, breakfast served

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1003)
"Great stay ❤️"
The price is S$276
includes taxes & fees
23 Jun - 24 Jun
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.