𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Upstate South Carolina (2026) - Fully Refundable Options

A bench, a bicycle, and a lake surrounded by trees.

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

A modern lobby with a reception desk, seating area, and a television screen.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

1. Best Western Spartanburg I-26

Spartanburg

Santhosh

S$143

includes taxes & fees

15 Oct - 16 Oct

An outdoor seating area with sofas, a fire pit, and string lights.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

2. Tru by Hilton Spartanburg

Spartanburg

Anthony

S$150

includes taxes & fees

1 Nov - 2 Nov

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A restaurant with a central island seating area, multiple tables, and a large mural on the wall.

A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

A spacious lobby with a bar area, seating, and large windows.

3. Hilton Garden Inn Spartanburg

Spartanburg

Yuliya

S$179

includes taxes & fees

30 Oct - 31 Oct

A modern living room with a fireplace, a flat-screen TV, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a refrigerator stocked with beverages, and shelves with snacks.

A modern kitchen with a central island, bar stools, and pendant lighting.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

4. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Duncan

Joseph

S$171

includes taxes & fees

4 Oct - 5 Oct

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.

5. Four Points by Sheraton Spartanburg

Spartanburg

John

S$152

includes taxes & fees

25 Oct - 26 Oct

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.

A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.

6. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Michael

S$145

includes taxes & fees

31 Oct - 1 Nov

A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

A bar with multiple shelves of liquor bottles and glasses hanging above.

A large, two-story house with a symmetrical facade, large windows, and a central entrance.

A modern living room with a fireplace, seating area, and a bar with shelves of bottles.

7. Hotel Hartness

Greenville

Kodjo

S$262

includes taxes & fees

4 Oct - 5 Oct

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A pool area with lounge chairs and a sign for Best Western Plus.

8. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

S$107

includes taxes & fees

18 Oct - 19 Oct

A modern interior with a fireplace, seating, and a wooden wall.

A modern living room with a flat-screen TV, a brown sofa, a small table, and a blue armchair.

A modern interior with seating areas, tables, a flat-screen TV, and a fireplace.

A hotel room with a flat-screen TV, a desk with a chair, a bed, and framed pictures on the wall.

9. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

Kathy

S$138

includes taxes & fees

19 Oct - 20 Oct

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A gaming arcade with various machines and a colorful carpet.

A large sports complex with multiple fields and tall light poles.

A modern building with a glass facade and a brick base, featuring a prominent entrance with a flag.

10. Comfort Suites Greenville Airport

Greenville

Ryan

S$135

includes taxes & fees

25 Oct - 26 Oct

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A Hampton Inn & Suites hotel with a modern facade, a covered entrance, and a brick pillar.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

11. Hampton Inn & Suites Greenville Airport, SC

Greenville

Marcella

S$141

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A gym with treadmills, elliptical machines, and weight machines.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

12. Comfort Suites At WestGate Mall

Spartanburg

tara

S$128

includes taxes & fees

1 Nov - 2 Nov

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A modern living room with a dining table, chairs, a sofa, a television, and bookshelves.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

A large hotel with a central courtyard, surrounded by manicured lawns and trees.

13. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

S$153

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

A modern lounge area with a green sofa, multiple tables, chairs, and a flat-screen TV.

A vending machine area with snacks and beverages, and a display of green apples.

14. Home2 Suites by Hilton Duncan

Duncan

Marina

S$167

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A modern lobby with a blue sofa, a round coffee table, and a brown armchair.

A hotel room with two beds, a desk, a TV, and a patterned carpet.

15. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Simpsonville

Shielder

S$112

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with hanging light fixtures and bar seating.

A modern bar area with a central island, bar stools, and overhead lighting.

A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.

A modern hotel room with a large desk, a comfortable sofa, and a bed.

16. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jeffery

S$161

includes taxes & fees

1 Nov - 2 Nov

A modern outdoor seating area with a blue sofa, white armchairs, and a black fire pit.

17. stayAPT Suites Greenville Greer BMW

Greer

Robert

S$156

includes taxes & fees

2 Oct - 3 Oct

A modern lobby with a fireplace, comfortable seating, and a flat-screen TV.

An outdoor seating area with wicker furniture and red cushions, surrounded by a stone fire pit.

A modern lobby with a large screen displaying a cityscape, a dark wooden reception desk, and a tall vase with branches.

A modern bar area with a counter, stools, and a menu board.

18. Courtyard Greenville-Spartanburg by Marriott

Greer

Susan

S$140

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a reception desk, seating area, and large windows.

A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

19. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

Bogdan

S$156

includes taxes & fees

1 Nov - 2 Nov

A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.

A modern kitchen with a granite countertop, a built-in grill, a microwave, and a coffee maker. There are two framed artworks on the wall and a refrigerator with a built-in ice maker.

A laundry room with two stacked washing machines and a single dryer.

A hotel room with a bed, a desk with a chair, a television, a window with curtains, and a bedside table with a lamp.

20. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Greenville

Charles

S$99

includes taxes & fees

18 Oct - 19 Oct

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Holiday Rentals in Upstate South Carolina

Aparthotel

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A covered porch with a welcome mat, two black Adirondack chairs, and a bench.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a microwave.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A two-story house with a front porch, a small garden, and a wooden fence.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Aparthotel

A modern building with outdoor seating and a garden.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

A row of modern, two-story buildings with a covered patio area.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A cabin in a forest with a small deck and outdoor seating area.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A compact living space with a sofa, a small round table, a wicker chair, a kitchen area with a microwave and cabinets, and a TV mounted on the wall.

A kitchen with a wooden countertop, a sink, a coffee maker, a toaster, and a window with a view of trees.

A bed with a white quilted cover, flanked by two wall-mounted nightstands with lamps.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A modern kitchen with white cabinets, stainless steel appliances, and a patterned rug.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Apartment

A large house with a spacious driveway and a pond in the background.

A modern kitchen with a central island, wooden cabinets, and a dining area with bar stools.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A wooden bridge leading to a playground with green grass and trees.

A modern kitchen with white cabinets, stainless steel appliances, and a marble countertop.

A backyard with a gazebo, a fire pit, and a covered seating area.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Cottage

A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.

A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.

A covered deck with wooden flooring, outdoor furniture, and a barbecue grill.

A modern kitchen with stainless steel appliances, white cabinetry, and a central island.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Seneca

"The best, perfect "

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

Mint House Greenville Downtown by Kasa

10/10 Excellent

"The space was nice. The bathroom was clean albeit somewhat dated but for a couple of nights it was totally fine! The overall quality of the space, bed, balcony and location was great for the price. Would book again"

Lakeside Lodge Clemson

10/10 Excellent

"My first time here. Lovely resort. Pool was awesome. Poolside restaurant had good sandwiches. I wish the breakfast was open before 10:00 am, but the free coffee was nice. I walked to Starbucks for breakfast. Room was spacious."

Hyatt Place Greenville Downtown

10/10 Excellent

"Very nice and peaceful"

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"clean room"

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"The room was very clean and comfortable. Staff was helpful and friendly. The lobby is to die for with the displays of Native American art and jewelry. A fun place e to stay with convenient location."

Comfort Inn & Suites Clemson - University Area

8/10 Good

"Great stay. Clean and conveniently located."

Upstate South Carolina Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Best Western Spartanburg I-26

2. Tru by Hilton Spartanburg

3. Hilton Garden Inn Spartanburg

4. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

5. Four Points by Sheraton Spartanburg

6. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

7. Hotel Hartness

8. Best Western Plus Greenville I-385 Inn & Suites

9. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

10. Comfort Suites Greenville Airport

11. Hampton Inn & Suites Greenville Airport, SC

12. Comfort Suites At WestGate Mall

13. Embassy Suites Greenville Golf Resort & Conference Center

14. Home2 Suites by Hilton Duncan

15. Fairfield Inn & Suites by Marriott Greenville Simpsonville

16. DoubleTree by Hilton Greenville Woodruff Road

17. stayAPT Suites Greenville Greer BMW

18. Courtyard Greenville-Spartanburg by Marriott

19. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

20. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

Carolina Camp Cedar

Greer Guest House < 1 Mi to Park & Downtown Area!

The Station by Compo Hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Carolina Landing RV Resort - Caravan Park

Clemson Memorabilia House

Claires Cottage ~ 4 Mi to Downtown Greenville!

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Mint House Greenville Downtown by Kasa

Lakeside Lodge Clemson

Hyatt Place Greenville Downtown

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Grand Bohemian Lodge Greenville, Autograph Collection

Comfort Inn & Suites Clemson - University Area

Hotels in Upstate South Carolina with star rating

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