
Popular airlines from Panama City to Medellín
- Avianca
Avianca
- Copa
Copa
- United
United
- Aeromexico
Aeromexico
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 40% on select hotels after you book a flight*
Cheap Flights from Panama City to Medellín (PTY-MDE)
Prices were available within the past 7 days and start at S$238 for one-way flights and S$457 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$457 Return, found 3 days ago
S$457
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$530 Return, found 3 days ago
S$530
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$538 Return, found 3 days ago
S$538
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$557 Return, found 3 days ago
S$557
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$575 Return, found 3 days ago
S$575
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$578 Return, found 3 days ago
S$578
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$590 Return, found 3 days ago
S$590
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$594 Return, found 3 days ago
S$594
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$610 Return, found 3 days ago
S$610
Return
found 3 days ago

Tue, 20 Jan - Sat, 24 Jan
PTY
Panama City
MDE
Medellin
S$615 Return, found 3 days ago
S$615
Return
found 3 days ago
Find the cheapest month to fly from Panama City (PTY) to Medellín (MDE)
February is typically the cheapest month to fly
From S$259 - S$441 per traveller.
Frequently asked questions
Travel information
Origin airport | Tocumen Intl. |
|---|---|
Destination airport | José María Córdova Intl. |
Return price | S$456 |
Distance | 539 km |
Average flight time | 1 hour 24 mins |
Book with confidence
Perfect flights from Panama City to Medellín
Your Journey from Panama City to Medellín
Start your unforgettable journey with Expedia. Our broad selection of flights from Panama City to Medellín caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
Choosing Your Ideal Flight
With Expedia, you have access to a wide range of airlines, including Copa, avianca, Aeromexico. Our selection of flights from Tocumen Intl. to José María Córdova Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
Maximizing Value with Panama City to Medellín Flights
Experience the joy of finding cheap flights from Tocumen Intl. to José María Córdova Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$238 and roundtrip prices from S$457*.
Pre-Flight Essentials
Ensure a smooth journey from Panama City to Medellín with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
Experience the Vibrant Medellín
Picture yourself stepping off the plane in Medellín and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
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Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Panama City to Medellín.
Beyond the Flight – Exploring Medellín
With Expedia, your adventure extends beyond the flight. Explore Medellín at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
Book Your Flight from Panama City to Medellín with Confidence
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*Note: Prices may vary based on availability and are subject to change.
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*Available to Expedia members.