Hotels in Clayton
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Clayton hotels
1. Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended StayClayton
9.0 out of 10, Wonderful, (3,289 reviews)
"Super nice staff and a beautiful hotel and area of town."
Steve
The price is S$142
includes taxes & fees
9 Aug - 10 Aug
2. Le Méridien St. Louis Clayton
Le Méridien St. Louis ClaytonClayton
8.8 out of 10, Excellent, (746 reviews)
"We loved the hotel and all the amenities spent my 5-year wedding anniversary here and will definitely stay here again!"
Ambreauna
The price is S$231
includes taxes & fees
1 Aug - 2 Aug
3. AC Hotel St. Louis Clayton
AC Hotel St. Louis ClaytonClayton
9.2 out of 10, Wonderful, (348 reviews)
"Welcoming staff and clean comfortable room in a great location."
Sherrill
The price is S$176
includes taxes & fees
9 Aug - 10 Aug
4. Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria AreaClayton
8.8 out of 10, Excellent, (1,002 reviews)
"It is nice hotel I’m so beautiful area! The neighborhood is so great! I was walking all my free time.
Lively hotel, very clean and comfortable. Will definitely stay here next time"
Olessya
The price is S$198
includes taxes & fees
2 Aug - 3 Aug
5. Residence Inn By Marriott St. Louis Clayton
Residence Inn By Marriott St. Louis ClaytonClayton
9.4 out of 10, Exceptional, (227 reviews)
"Our stay was very good!"
Donna
The price is S$270
includes taxes & fees
23 Aug - 24 Aug
6. Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio HotelClayton
8.4 out of 10, Very good, (597 reviews)
"I always stay at the Seven Gables Inn while visiting St. Louis - fantastic, walkable neighborhood, for central STL, including vintage shopping & dining options. The boutique hotel is very ‘Old St. Louis’ with extremely modern, comfortable, quiet and safe rooms."
Jennifer
The price is S$229
includes taxes & fees
16 Aug - 17 Aug
7. The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. LouisClayton
9.2 out of 10, Wonderful, (576 reviews)
"Friendly staff and very clean room."
Karen
The price is S$752
includes taxes & fees
2 Aug - 3 Aug
8. Homewood Suites by Hilton St Louis - Galleria
Homewood Suites by Hilton St Louis - GalleriaClayton
7.8 out of 10, Good, (1,002 reviews)
"Our room was clean and quiet! We have a family of 6 and all slept comfortably! Staff was super nice upon check in and check out! Great location with lots around to do as well!"
Kristin
The price is S$212
includes taxes & fees
9 Aug - 10 Aug
9. The Knight Center at Washington University
The Knight Center at Washington University1.3 km from Clayton
9.4 out of 10, Exceptional, (638 reviews)
"Highly recommend staying at this hotel."
Carla
The price is S$218
includes taxes & fees
9 Aug - 10 Aug
10. Drury Plaza Hotel St. Louis Brentwood
Drury Plaza Hotel St. Louis Brentwood2.5 km from Clayton
9.6 out of 10, Exceptional, (1,022 reviews)
"Great place to vacation. Great staff and clean rooms."
Shaleria
The price is S$208
includes taxes & fees
9 Aug - 10 Aug
11. SpringHill Suites St. Louis Brentwood
SpringHill Suites St. Louis Brentwood2.4 km from Clayton
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice place to stay."
Elzbieta
The price is S$190
includes taxes & fees
9 Aug - 10 Aug
12. The Cheshire
The Cheshire1.8 km from Clayton
8.8 out of 10, Excellent, (1,004 reviews)
"We loved this hidden gem."
Arthur
The price is S$253
includes taxes & fees
2 Aug - 3 Aug
13. Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn & Suites St. Louis at Forest ParkDogtown, 3.9 km from Clayton
9.4 out of 10, Exceptional, (1,006 reviews)
"Clean rooms, comfortable beds, friendly staff."
Krystina
The price is S$211
includes taxes & fees
9 Aug - 10 Aug
14. Moonrise Hotel
Moonrise Hotel2.6 km from Clayton
9.0 out of 10, Wonderful, (2,004 reviews)
"My FAVORITE place to stay when I'm in the LOU. Can't go wrong with this hotel and it's safe and convenient location to all the hot spots. The staff was amazing and helpful."
Darci
The price is S$230
includes taxes & fees
5 Aug - 6 Aug
15. AC Hotel St. Louis Central West End
AC Hotel St. Louis Central West EndCentral West End, 5.3 km from Clayton
9.0 out of 10, Wonderful, (795 reviews)
"Great location."
Blake
The price is S$218
includes taxes & fees
2 Aug - 3 Aug
16. The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. LouisCentral West End, 5.1 km from Clayton
9.0 out of 10, Wonderful, (1,012 reviews)
"Enjoyed our stay!"
Patricia
The price is S$301
includes taxes & fees
9 Aug - 10 Aug
17. Hotel Indigo St Louis - Central West End by IHG
Hotel Indigo St Louis - Central West End by IHGCentral West End, 5.5 km from Clayton
8.8 out of 10, Excellent, (1,003 reviews)
"Great stay!"
Morgan
The price is S$199
includes taxes & fees
9 Aug - 10 Aug
18. Aloft by Marriott St. Louis Cortex
Aloft by Marriott St. Louis CortexCentral West End, 6.3 km from Clayton
8.6 out of 10, Excellent, (987 reviews)
"Very nice hotel staff were great water was hot the entire stay clean rooms"
Khristina
The price is S$172
includes taxes & fees
9 Aug - 10 Aug
19. Home2 Suites by Hilton St. Louis/Forest Park
Home2 Suites by Hilton St. Louis/Forest ParkThe Grove, 5.6 km from Clayton
8.6 out of 10, Excellent, (1,005 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
paullita jeanne
The price is S$211
includes taxes & fees
24 Aug - 25 Aug
20. Drury Inn & Suites St. Louis Forest Park
Drury Inn & Suites St. Louis Forest Park4.1 km from Clayton
9.4 out of 10, Exceptional, (1,007 reviews)
"Clean rooms, Breakfast was great. Adjoining restaurant was convenient and delicious."
Sarah
The price is S$225
includes taxes & fees
9 Aug - 10 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Clayton
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Residence Inn By Marriott St. Louis Clayton | 9.4 Exceptional 227 reviews | View | ||||||
 AC Hotel St. Louis Clayton | 9.2 Wonderful 348 reviews | View | ||||||
 The Ritz-Carlton, St. Louis | 9.2 Wonderful 576 reviews | View | ||||||
 Clayton Plaza Hotel & Extended Stay | 9.0 Wonderful 3,289 reviews | View | ||||||
 Le Méridien St. Louis Clayton | 8.8 Excellent 746 reviews | View |
Where to stay in Clayton
Find the best Clayton areas for the activities you enjoy most.
Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Photo by Terry Eaves
Open Photo by Terry Eaves
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.
Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.
Top Clayton Hotel Reviews
Pear Tree Inn St. Louis Near Union Station
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Anheuser-Busch Brewery
- Hotels near Barnes Jewish Hospital
- Bella Villa Hotels
- Gay friendly Hotels in Berkeley
- Hotels with free wifi in Brentwood
- Villas in Brentwood
- Central West End Hotels
- Hotels near City Museum
- Gay friendly Hotels in Clayton-Tamm
- Concord Hotels
- Crestwood Hotels
- Hotels with free wifi in Creve Coeur
- Hyatt Hotels in Creve Coeur
- Des Peres Hotels
- Hotels near Dome at America’s Center
- Downtown St. Louis Hotels
- Hotels near Enterprise Center
- Frontenac Hotels
- Hotels near Gateway Arch
- Green Park Hotels
- Hotels near Horseshoe St. Louis Casino
- Cabin Rentals in Kirkwood
- Cottages in Kirkwood
- Hotels near Lambert-St. Louis Intl.
- Lindenwood Park Hotels
- Hotels with kitchenette in Maryland Heights
- Maryland Heights Hotels
- Hotels near Missouri Botanical Gardens and Arboretum
- Overland Hotels
- Richmond Heights Hotels
- Rock Hill Hotels
- Shaw Hotels
- Soulard Hotels
- St. Ann Hotels
- Beach Resorts in St. Louis
- Boutique Hotels in St. Louis
- Casino Hotels in St. Louis
- Gay friendly Hotels in St. Louis
- Hotels with Balcony in St. Louis
- Hotels with free airport shuttle in St. Louis
- Hotels with smoking rooms in St. Louis
- Luxury Hotels in St. Louis
- Red Roof Inn Hotels in St. Louis
- Royal Orchid Hotels in St. Louis
- St. Louis Hotels
- Aparthotels in St. Louis
- Hotels near St. Louis Union Station
- Hotels near St. Louis Zoo
- University City Hotels
- Hotels near Washington University in St. Louis
- Flights to Green Park
- Flights to Maryland Heights
- Flights to St. Louis
- Flights to Sunset Hills
- Flights from Atlanta (ATL) to St. Louis (STL)
- Flights from Branson (BKG) to St. Louis (STL)
- Flights from Bangkok (BKK) to St. Louis (STL)
- Flights from Mumbai (BOM) to St. Louis (STL)
- Flights from Boston (BOS) to St. Louis (STL)
- Flights from Colorado Springs (COS) to St. Louis (STL)
- Flights from Dallas (DFW) to St. Louis (STL)
- Flights from Daet (DTE) to St. Louis (STL)
- Flights from Echuca (ECH) to St. Louis (STL)
- Flights from Evanston (EVW) to St. Louis (STL)
- Flights from Fergus Falls (FFM) to St. Louis (STL)
- Flights from Fortaleza (FOR) to St. Louis (STL)
- Flights from Frankfurt (FRA) to St. Louis (STL)
- Flights from Guaymas (GYM) to St. Louis (STL)
- Flights from Seoul (ICN) to St. Louis (STL)
- Flights from Ilulissat (JAV) to St. Louis (STL)
- Flights from Kahramanmaras (KCM) to St. Louis (STL)
- Flights from Los Angeles (LAX) to St. Louis (STL)
- Flights from Chennai (MAA) to St. Louis (STL)
- Flights from Chicago (ORD) to St. Louis (STL)
- Flights from Portland (PDX) to St. Louis (STL)
- Flights from San Antonio (SAT) to St. Louis (STL)
- Flights from San Angelo (SJT) to St. Louis (STL)
- Flights from Orange County (SNA) to St. Louis (STL)
- Flights from Sarasota (SRQ) to St. Louis (STL)
- Flights from Vancouver (YVR) to St. Louis (STL)
- Flights from Toronto (YYZ) to St. Louis (STL)
- Chaifetz Arena
- Citygarden
- Visit Cool Valley
- Forest Park
- Gateway Arch National Park
- Grant's Farm
- Magic House - St. Louis Children's Museum
- Missouri Botanical Gardens and Arboretum
- Visit Olivette
- Overland Holidays
- Pagoda Circle
- St. Louis Art Museum
- Visit Downtown St. Louis
- Visit Lindenwood Park
- St. Louis Holidays