Hotels in Clayton

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Our top choices for Clayton hotels

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3030)
"Clean room, good breakfast and good location "
United States
Martin
The price is S$137
includes taxes & fees
14 Dec - 15 Dec
Clayton Plaza Hotel & Extended Stay

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Clayton
9.2 out of 10, Wonderful, (222)
"Enjoyed my stay"
United States
Kingsley
The price is S$184
includes taxes & fees
21 Dec - 22 Dec
AC Hotel St. Louis Clayton

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (676)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is S$181
includes taxes & fees
19 Dec - 20 Dec
Le Méridien St. Louis Clayton

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is S$753
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
9.0 out of 10, Wonderful, (911)
"Clean, nice staff, hot breakfast with variety of options"
United States
Tamara
The price is S$169
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Residence Inn By Marriott St. Louis Clayton

Residence Inn By Marriott St. Louis Clayton
3.0 star property
Clayton
9.2 out of 10, Wonderful, (193)
"Clean large rooms,comfortable beds"
United States
RAGHAV
The price is S$236
includes taxes & fees
19 Dec - 20 Dec
Residence Inn By Marriott St. Louis Clayton

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very good, (577)
"Love this place."
United States
Robert
The price is S$196
includes taxes & fees
14 Dec - 15 Dec
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Homewood Suites by Hilton St Louis - Galleria

Homewood Suites by Hilton St Louis - Galleria
3.0 star property
Clayton
8.0 out of 10, Very good, (1002)
"The rooms were clean and comfortable."
United States
Kelly
The price is S$166
includes taxes & fees
19 Dec - 20 Dec
Homewood Suites by Hilton St Louis - Galleria

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
13.6 km from Clayton
9.0 out of 10, Wonderful, (1446)
"Awesome place to stay!!"
United States
Kaitlyn
The price is S$143
includes taxes & fees
21 Dec - 22 Dec
River City Casino & Hotel

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
20.1 km from Clayton
9.4 out of 10, Exceptional, (1001)
"Love this hotel. "
United States
Lisa
The price is S$170
includes taxes & fees
1 Jan - 2 Jan, 2026
Country Inn & Suites by Radisson, St. Charles Historic District

Moonrise Hotel

Moonrise Hotel
4.0 star property
2.6 km from Clayton
9.0 out of 10, Wonderful, (1912)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is S$194
includes taxes & fees
18 Dec - 19 Dec
Moonrise Hotel

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
20 km from Clayton
9.6 out of 10, Exceptional, (1001)
"Hotel was very clean."
United States
christine
The price is S$172
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel St. Louis St. Charles

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
20.5 km from Clayton
8.0 out of 10, Very good, (1000)
"It was perfect, and the staff were very helpful!"
United States
Susan
The price is S$130
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus The Charles Hotel

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 10.9 km from Clayton
8.8 out of 10, Excellent, (1000)
"Clean room and very helpful staff"
United States
Amy
The price is S$171
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott St Louis Creve Coeur

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 12 km from Clayton
8.4 out of 10, Very good, (4003)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is S$136
includes taxes & fees
21 Dec - 22 Dec
Hyatt Regency St. Louis at The Arch

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
17.2 km from Clayton
7.4 out of 10, Good, (1000)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is S$89
includes taxes & fees
6 Jan - 7 Jan, 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
20.3 km from Clayton
8.4 out of 10, Very good, (1002)
"Nice staff at reception. "
United States
Denise
The price is S$117
includes taxes & fees
14 Dec - 15 Dec
Comfort Suites St Charles - St Louis

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
19.8 km from Clayton
8.4 out of 10, Very good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is S$251
includes taxes & fees
14 Dec - 15 Dec
Ameristar Casino Resort and Spa

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
18.3 km from Clayton
8.4 out of 10, Very good, (2216)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is S$177
includes taxes & fees
6 Jan - 7 Jan, 2026
Hollywood Casino & Hotel St. Louis

Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
26.6 km from Clayton
8.2 out of 10, Very good, (1001)
"This was an amazing stay"
United States
Madison
The price is S$138
includes taxes & fees
21 Dec - 22 Dec
Country Inn & Suites by Radisson, St. Peters, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Clayton

Find the best Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Clayton Hotel Reviews

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Frequently asked questions

What's it like in Clayton?
Clayton is a welcoming neighbourhood known for its array of dining options and sporting events. Make sure that you visit Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.
Where is the best place to stay in Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Clayton. This hotel offers 2 restaurants and 2 bars. Other top choices in the neighbourhood include Residence Inn By Marriott St. Louis Clayton and The Ritz-Carlton, St. Louis.
How many hotels will I find in Clayton?
Expedia has 9 Clayton hotels and other accommodation options, and one might make a good home base for venturing out into the greater St. Louis area.
If I need to cancel my hotel reservation in Clayton, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the top deals on offer in Clayton.
What are the top things to see and do in Clayton?
A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, Tao Tennis Center and Center of Creative Arts are also worth a stop.
How can I get around Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.