Santo Spirito

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A historic church with a dome and bell tower, surrounded by trees and a fountain in a public square.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

S$26
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

S$42
per adult
74% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Michaelangelo's David

Accademia timed-entry Ticket with App Guide

S$57
per adult
90% of travellers recommend
Accademia timed-entry Ticket with App Guide
Florence's Accademia Gallery Timed Entry Ticket

Florence's Accademia Gallery Timed Entry Ticket

S$51
per adult
88% of travellers recommend
Florence's Accademia Gallery Timed Entry Ticket
Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine

Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine

S$116
per adult
88% of travellers recommend
Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine
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Florence: Pizza & Gelato Masterclass Morning, Afternoon or Evening Delight

S$113
per adult
94% of travellers recommend
Florence: Pizza & Gelato Masterclass Morning, Afternoon or Evening Delight
See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is S$311 per night from 28 Oct to 29 Oct
S$311
28 Oct - 29 Oct
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
9.8/10 Exceptional! (733 reviews)
"Absolutely amazing hotel. Beautiful grounds and building in a nice, quiet part of the neighborhood, but still so walkable and close to churches, museums, restaurants, etc. Cherish at check-in gave us some great recommendations for food nearby. Had some of the best baked goods I've ever had at breakfast ..."

Reviewed on 28 Sept, 2026

Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is S$257 per night from 22 Oct to 23 Oct
S$257
22 Oct - 23 Oct
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza del Duomo ...
9.2/10 Wonderful! (333 reviews)
"The hotel was perfect for what we needed and all the staff were friendly and helpful Easy to get around and great location Host was a delight"

Reviewed on 30 Sept, 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is S$208 per night from 30 Oct to 31 Oct
S$208
30 Oct - 31 Oct
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very good! (1,000 reviews)
"The entrance, the building, the lobby looked very well and promising. Room was small but ok. The shower was terrible, poor mainteined. Room decoration looked agressive. Breakfast was great. Location little far from downtown"

Reviewed on 6 Sept, 2026

UNA Hotels Vittoria Firenze
Casa Santo Nome di GesĆ¹

Casa Santo Nome di GesĆ¹

Piazza del Carmine, 21 Florence FI
The price is S$244 per night from 28 Oct to 29 Oct
S$244
28 Oct - 29 Oct
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
Casa Santo Nome di GesĆ¹
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI
The price is S$131 per night from 18 Oct to 19 Oct
S$131
18 Oct - 19 Oct
includes taxes & fees
Stay at this hostel in Florence. Enjoy free Wi-Fi, daily housekeeping and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza del ...
7.8/10 Good! (64 reviews)
"No"

Reviewed on 30 Jul, 2026

Hostel Santa Monaca
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Fully refundableReserve now, pay when you stay
The price is S$358 per night from 24 Oct to 25 Oct
S$358
24 Oct - 25 Oct
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,181 reviews)
"Wonderful location and ideal living space, would have loved to stay there longer"

Reviewed on 30 Sept, 2026

Palazzo Mannaioni Suites
See all 540 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at UnitĆ  Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito