Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and stunning cathedral in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the notable monuments and stunning cathedral in this vibrant area.
Things to do
Florence Accademia Gallery Tour with Entrance Ticket Included
Florence: Timed Entry to Michelangelo's David + Audio App
Pisa, Siena and San Gimignano day trip from Florence
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Cinque Terre: the scent of the sea from Florence
Top hotels in Santo Spirito
Hotel Horto Convento
Beautiful building and rooms, interesting
Reviewed on 6 Jan, 2026
Palazzo Mannaioni Suites
Beautiful, clean and staff were respectful & helpful! I love the place!
Reviewed on 30 Dec, 2025
UNA Hotels Vittoria Firenze
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!
Reviewed on 1 Jan, 2026
La Torre Del Cestello
Beautiful place to stay. Just outside of the bustle but walking within distance. Warmly welcomed and staff were lovely.
Reviewed on 25 Dec, 2025
Oltrarno Splendid
It was a great stay. The renovation style is very tasteful.
Reviewed on 29 Dec, 2025
Casa Santo Nome di Gesù
Really a nice place, like the room style and good for family stay!
Reviewed on 1 Jan, 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.
