Hotels in Santo Spirito

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in Santo Spirito

AdAstra Suites

9.8 out of 10, Exceptional, (211)
"Had a lovely 3 day stay here with my daughter. Lovely staff and great breakfast . Hope to come again with family in September "
The price is S$420
includes taxes & fees
6 Jul - 7 Jul
AdAstra Suites

Palazzo D'Oltrarno - Residenza D'Epoca

9.4 out of 10, Exceptional, (36)
"Gulia & Guissepe were so friendly and accommodating during our check in and stay. Great hidden gem as the property asked all to keep silence; great to have a quiet sanctuary away from the hubbub of city life! Nice view from our #5."
Palazzo D'Oltrarno - Residenza D'Epoca

Oltrarno Splendid

9.8 out of 10, Exceptional, (86)
"Great that it was completely separate and quiet - an oasis in a hot and bustling city yet very close to sights, restaurants etc."
The price is S$341
includes taxes & fees
9 Jul - 10 Jul
Oltrarno Splendid

SPIRIT OF FLORENCE Boutique Rooms

10.0 out of 10, Exceptional, (21)
"My husband and I enjoyed our stay here! Large rooms and bathrooms, wonderful location, and great staff! "
The price is S$264
includes taxes & fees
4 Aug - 5 Aug
SPIRIT OF FLORENCE Boutique Rooms

Luxury Petra San Frediano by Mmega

9.4 out of 10, Exceptional, (3)
"This property accommodated our family of 7 very nicely. We would stay there again if we returned to Florence. There are a few things people should know in booking this property. The location was very nice but it is a 20-25 minute walk to many of the primary attractions of Florence. Also, the adjacent plaza can get quite noisy on the weekends or holidays as people congregate there. The windows/shutters blocked most of the noise in most of the rooms but there were was a room or two where the noise...
The price is S$566
includes taxes & fees
3 Aug - 4 Aug
Luxury Petra San Frediano by Mmega

La Fonderia Firenze

9.6 out of 10, Exceptional, (155)
"Great location, wonderful staff, awesome room. Will definely stay again! "
The price is S$196
includes taxes & fees
27 Jul - 28 Jul
La Fonderia Firenze

Hotel Relais Il Cestello

3.0 star property
8.6 out of 10, Excellent, (241)
"Good hotel"
Hotel Relais Il Cestello

Soggiorno Alessandra

8.6 out of 10, Excellent, (85)
"Soggiorno Alessandra is a great value! Very close to everything in Florence, and with room for our entire family in one room with a loft space!"
Soggiorno Alessandra

Mamo Florence - Maddalena Apartment

10.0 out of 10, Exceptional, (1)
"Fantastic top floor apartment in medieval building just beyond the Palazzo Pitti on the quieter side of the Arno. There's a cafe and a supermarket nearby, a very popular pizzeria and Santo Spirito 5 minutes away and the heart of the city is just 10 to 15 minutes walk away. The apartment had everything we needed for a family of 5, great cooking facilities and a neat and tidy bathroom. We'd definitely stay there again if we return to Florence. "
The price is S$343
includes taxes & fees
18 Jul - 19 Jul
Mamo Florence - Maddalena Apartment

1900 Artevita

8.8 out of 10, Excellent, (167)
"Excellent stay - easy walk to centre - highly recommended"
The price is S$190
includes taxes & fees
9 Jul - 10 Jul
1900 Artevita

Torre di Bellosguardo

4.0 star property
9.0 out of 10, Wonderful, (96)
"Amazing hotel and Staff! Definitely coming here again during our next trip to Italy!"
The price is S$798
includes taxes & fees
6 Jul - 7 Jul
Torre di Bellosguardo

Ottantotto Firenze

9.6 out of 10, Exceptional, (159)
"Beautiful rooms and friendly staff "
The price is S$343
includes taxes & fees
20 Jul - 21 Jul
Ottantotto Firenze

Ostello Tasso

9.0 out of 10, Wonderful, (28)
"Very clean (room and shared bath), quiet area in general. Definitely recommend "
Ostello Tasso

Drom Florence Rooms & Apartments

9.8 out of 10, Exceptional, (123)
"I loved this place and made me want to go back and stay for a while!!! The host was so nice and accommodating. This is a must book place if you are looking for Florence charm and don’t mind a 20 "
Drom Florence Rooms & Apartments

Cestello Suite by Mmega

8.0 out of 10, Very good, (4)
"Close to train station and most of the places you will be visiting. Checkin was easy and fast. Will definitely stay again!"
The price is S$278
includes taxes & fees
7 Jul - 8 Jul
Cestello Suite by Mmega

Nerli Prestige by Mmega

8.6 out of 10, Excellent, (8)
"Wonderful place! Spacious and close to everything. The beds were very comfortable. We loved staying here."
The price is S$374
includes taxes & fees
6 Jul - 7 Jul
Nerli Prestige by Mmega

Home in Florence

8.8 out of 10, Excellent, (68)
"Perfect place, super friendly owners, really helpful. "
The price is S$149
includes taxes & fees
6 Jul - 7 Jul
Home in Florence

La Torre Del Cestello

9.0 out of 10, Wonderful, (189)
"The innkeepers are incredibly helpful, the room was lovely, and in a great location. They helped us celebrate our anniversary! We would stay again and again. "
The price is S$187
includes taxes & fees
5 Aug - 6 Aug
La Torre Del Cestello

Hotel Palazzo Guadagni

3.0 star property
9.0 out of 10, Wonderful, (196)
"This very hip hotel features a stylish rooftop bar—the hottest spot in the city—along with cool and friendly front desk staff, amazing rooms adorned with antique furniture and beautiful wall paintings, and stunning views throughout."
The price is S$306
includes taxes & fees
6 Jul - 7 Jul
Hotel Palazzo Guadagni

UNA HOTELS Vittoria Firenze

4.0 star property
8.4 out of 10, Very good, (1000)
"It was average really. Needs to be updated in the rooms blobby area and outside was very nice "
The price is S$178
includes taxes & fees
6 Jul - 7 Jul
UNA HOTELS Vittoria Firenze
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
Historic Centre of Florence map

Historic Centre of Florence

9 out of top 10 points of interest in this area

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo map

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

Santa Maria Novella map

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni map

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Croce map

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Frequently asked questions

What is Santo Spirito like?

Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.

What's a favourite place to stay in Santo Spirito?

Based on Expedia customer reviews, AdAstra Suites is the highest ranked property in Santo Spirito. This B&B is a short 11-minute walk from Ponte Vecchio, and it offers free breakfast and free WiFi. Other favourite options in the area include Oltrarno Splendid and Ottantotto Firenze.

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 466 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.

What can I see and do in this Florence neighbourhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. Uffizi Gallery and Cathedral of Santa Maria del Fiore are some popular places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.