Hotels in Santo Spirito

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Santo Spirito

Hotel Horto Convento

4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (590)
"Excellent staff, so friendly and helpful. Lovely hotel in a great location. "
United Kingdom
Emma
The price is S$164
includes taxes & fees
9 Dec - 10 Dec
Hotel Horto Convento

Foresteria Valdese di Firenze - Casa per Ferie

Santo Spirito
8.8 out of 10, Excellent, (192)
"The staff was very helpful and room was clean "
United States
Cinda
Foresteria Valdese di Firenze - Casa per Ferie

Casa Santo Nome di Gesù

Santo Spirito
8.8 out of 10, Excellent, (337)
"I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced. "
United States
Marcie
Casa Santo Nome di Gesù

Palazzo Mannaioni Suites

4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1067)
"Clean and great staff"
United States
lauren
Palazzo Mannaioni Suites

Hotel Firenze 2000

2.0 star property
Santo Spirito
7.2 out of 10, Good, (189)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is S$126
includes taxes & fees
14 Dec - 15 Dec
Hotel Firenze 2000

La Torre Del Cestello

Santo Spirito
9.0 out of 10, Wonderful, (223)
"Great location and great rooms"
United States
David
La Torre Del Cestello

Oltrarno Splendid

Santo Spirito
10.0 out of 10, Exceptional, (96)
"It was Wonderful!!!"
United States
MARGARITA
The price is S$262
includes taxes & fees
1 Dec - 2 Dec
Oltrarno Splendid

Palazzo D'Oltrarno - Residenza D'Epoca

Santo Spirito
9.4 out of 10, Exceptional, (46)
"Excellent place to stay!"
United States
Diane
The price is S$169
includes taxes & fees
25 Nov - 26 Nov
Palazzo D'Oltrarno - Residenza D'Epoca

Della Calza Spa & Foresteria

Santo Spirito
The price is S$384
includes taxes & fees
18 Nov - 19 Nov
Della Calza Spa & Foresteria

La Fonderia Firenze

Santo Spirito
9.6 out of 10, Exceptional, (172)
"Breakfast outside was lovely"
United States
Kenneth
The price is S$170
includes taxes & fees
24 Nov - 25 Nov
La Fonderia Firenze

Torre di Bellosguardo

4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103)
"Beautiful property and wonderful staff."
United States
Brad
The price is S$555
includes taxes & fees
18 Nov - 19 Nov
Torre di Bellosguardo

AdAstra Suites

Santo Spirito
9.8 out of 10, Exceptional, (219)
"Staff was absolutely wonderful!!! "
United States
Trisha
The price is S$273
includes taxes & fees
4 Dec - 5 Dec
AdAstra Suites

Hotel Palazzo Guadagni

3.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (200)
"Hotel Palazzo was stunning. I would definitely stay here again and I already can't wait to! The staff were so friendly and made you feel right at home. Everything was walking distance and the area was incredible!"
United States
Annyelis
The price is S$285
includes taxes & fees
23 Nov - 24 Nov
Hotel Palazzo Guadagni

Drom Florence Rooms & Apartments

Santo Spirito
9.8 out of 10, Exceptional, (134)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments

1900 Artevita

Santo Spirito
8.8 out of 10, Excellent, (176)
"This property is great and the manager is very kind and helpful."
United States
Elizabeth
The price is S$132
includes taxes & fees
18 Nov - 19 Nov
1900 Artevita

Hostel Santa Monaca

Santo Spirito
8.0 out of 10, Very good, (60)
"I found it easy to move around and walked everywhere. Staff super friendly. Ten people in one room was a bit much, but overall comfortable. Thank you.!"
Canada
Alma
Hostel Santa Monaca

Residenza D'Epoca Al Numero 8

Santo Spirito
8.8 out of 10, Excellent, (137)
"Very nice place to stay. closed to good restaurantsand shopping. "
United States
JULIO
Residenza D'Epoca Al Numero 8

Ottantotto Firenze

Santo Spirito
9.6 out of 10, Exceptional, (169)
"Fabulous hotel , breakfast was amazing , great location "
United Kingdom
SAMANTHA
The price is S$345
includes taxes & fees
25 Nov - 26 Nov
Ottantotto Firenze

L'Antica Porta Boutique B&B

Santo Spirito
8.8 out of 10, Excellent, (18)
"Clean and comfy room | Easy transportation | Safe"
United States
Gabriel
The price is S$138
includes taxes & fees
18 Nov - 19 Nov
L'Antica Porta Boutique B&B

Soderini Apartments by MMega

Santo Spirito
9.6 out of 10, Exceptional, (7)
"Having laundry in the room was great! The location was nice. Easy to walk to tourist sites. Grocery store was almost next door. Gelato store was almost next door. All the bases were covered!"
Canada
Brett
The price is S$231
includes taxes & fees
18 Nov - 19 Nov
Soderini Apartments by MMega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito with a pool

Top guest rated hotels in Santo Spirito

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Via de' Calzaiuoli or Giotto's Campanile while you're exploring the neighbourhood.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favourite options in the area include SPIRIT OF FLORENCE Boutique Rooms and Ottantotto Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 478 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza del Carmine, Santa Maria della Carmine and Brancacci Chapel. When you're sightseeing in Florence, Il Nabucco di Matteo Gabellini and Teatro Comunale Florence are also worth a stop.