A grand church interior with high vaulted ceilings, large columns, and a central altar.

Hotels in Santo Spirito

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Our top choices for Santo Spirito hotels

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (273 reviews)
"Great location in Oltrarno; clean, comfortable and well-appointed room; helpful and responsive staff. Ask for restaurant recommendations, they won’t disappoint."
United States
Robert
The price is S$174
includes taxes & fees
4 Jul - 5 Jul
La Torre Del Cestello

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
8.0 out of 10, Very good, (5 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is S$350
includes taxes & fees
29 Jul - 30 Jul
Mamo Florence - Bice & Krizia Apartments

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (227 reviews)
"Great stay"
United States
Eric
The price is S$153
includes taxes & fees
10 Jul - 11 Jul
Foresteria Valdese di Firenze - Casa per Ferie

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (681 reviews)
"Beautiful hotel, comfortable bed and well-appointed room. The friendly staff helped with directions, restaurant recommendations, and reservations. Good breakfast, great bartender at the bar in the lobby. Would stay again and highly recommend."
United States
Mari
The price is S$257
includes taxes & fees
20 Jul - 21 Jul
Hotel Horto Convento

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (128 reviews)
"We absolutely loved our 3-night stay at Oltrarno Splendid - a true hidden Gem in the best location - with cool shopping vibes and on the quieter side of the river! We loved the neighborhood feel and soaring ceilings for an authentice Florence stay with all the modern ammenities. Beautiful breakfast included and exceptionally friendly, helpful staff - shout-outs to Davide & Barbara!"
Canada
Leanne
The price is S$382
includes taxes & fees
2 Aug - 3 Aug
Oltrarno Splendid

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (231 reviews)
"What a special place! Beautiful place, large room and beautifully garden and comfortable and welcoming gathering/common area space where we were treated like old friends. Cannot wait to return."
United States
Mary Clare
The price is S$369
includes taxes & fees
29 Jul - 30 Jul
AdAstra Suites

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (174 reviews)
"Really beautiful property and wonderful room. Hotel is immaculately clean and we thought the hotel had been renovated to a beautiful finish. We let the hotel know we were staying for our 10 year anniversary, and a bottle of Prosecco was left in our room with a note, which was extremely kind. A great location to stay in, just across the river. Passcode is provided for front door so can come and go as please. Have booked to stay in again in October!"
United Kingdom
Samantha
The price is S$313
includes taxes & fees
14 Jul - 15 Jul
Ottantotto Firenze

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
8.6 out of 10, Excellent, (26 reviews)
"Very goord place to stay"
United States
Victor
The price is S$173
includes taxes & fees
2 Aug - 3 Aug
L'Antica Porta Boutique B&B

Fiammetta by MMega

Fiammetta by MMega
Santo Spirito
The price is S$320
includes taxes & fees
26 Jul - 27 Jul
Fiammetta by MMega

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is S$190
includes taxes & fees
19 Jul - 20 Jul
La Fonderia Firenze

Casa Vittoria by Mmega

Casa Vittoria by Mmega
Santo Spirito
2.0 out of 10, (1 review)
"El trato de la persona a cargo fue terrible nos cobró extra del precio de la renta 90 euros de limpieza solo en efectivo con una actitud muy arrogante más $35 por llegar una hora tarde después de su checkin, nunca tuvimos internet lo cual le avisamos a la brevedad y su respuesta fue que el no tenía el internet en su cartera! Terrible el trato! Nunca regresó a arreglar el internet! En la casa no hay señal y tampoco internet! "
Mexico
Estefania
The price is S$279
includes taxes & fees
5 Jul - 6 Jul
Casa Vittoria by Mmega

Mamo Florence - Aleardi Roof Apartment

Mamo Florence - Aleardi Roof Apartment
Santo Spirito
10.0 out of 10, Exceptional, (1 review)
"Excelente lugar y relacion precio - estancia"
Mexico
Roberto Carlos
The price is S$314
includes taxes & fees
5 Jul - 6 Jul
Mamo Florence - Aleardi Roof Apartment

Vettori Hideaway by MMega

Vettori Hideaway by MMega
Santo Spirito
The price is S$273
includes taxes & fees
4 Jul - 5 Jul
Vettori Hideaway by MMega

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,134 reviews)
"The management waswarm and welcoming and helped assist us with restaurants, travel and sightseeing."
United States
Janet
The price is S$254
includes taxes & fees
5 Jul - 6 Jul
Palazzo Mannaioni Suites

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (195 reviews)
"Pros: - great location. In quiet neighbourhood yet walkable to everywhere. Close to lovely restaurants and bakery. - "
United Kingdom
Jennifer
The price is S$160
includes taxes & fees
5 Jul - 6 Jul
1900 Artevita

Cosimo by MMega

Cosimo by MMega
Santo Spirito
9.2 out of 10, Wonderful, (18 reviews)
"Beautiful place, clean specious rooms, great location. There were all needed amenities: laundry, dishwasher, hairdryer and etc. Highly recommend!"
United States
Oxana
The price is S$309
includes taxes & fees
22 Jul - 23 Jul
Cosimo by MMega

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (151 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
Drom Florence Rooms & Apartments

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.4 out of 10, Very good, (40 reviews)
"Great stay! The place was clean, comfortable, and exactly as described. Would definitely stay again"
United States
Diana
The price is S$250
includes taxes & fees
2 Aug - 3 Aug
Appartamenti degli Artisti by Mmega

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (158 reviews)
"Excellent place"
United States
Laura Patricia
The price is S$174
includes taxes & fees
4 Jul - 5 Jul
Residenza D'Epoca Al Numero 8

Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (102 reviews)
"Good location"
France
Leana
The price is S$109
includes taxes & fees
17 Jul - 18 Jul
Palazzo Oliveto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Signoria and Uffizi Gallery are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Charming Santo Spirito Square: A vibrant hub filled with trendy cafés and artisan shops, ideal for leisurely afternoons.
  • Historic San Spirito Church: Admire the stunning architecture and rich history of this iconic church, a true gem of the Renaissance.
  • Wine Tours: Savour exquisite local wines on delightful tours through the picturesque Tuscan countryside.
  • Art and Culture: Immerse yourself in the local heritage while exploring nearby palaces and the artistic legacy of Fra Bartolomeo.
  • Varied Accommodation: Enjoy a range of lodging options, from quaint B&Bs to stylish hotels, showcasing unique Tuscan charm.

Find great hotels near Santo Spirito

Discover a delightful blend of charm and modernity in Santo Spirito, Florence, where a range of accommodations awaits. From quaint bed and breakfasts to stylish hotels, you'll find options featuring antique furniture and unique lofts. Enjoy pet-friendly services and city-themed experiences while exploring nearby attractions like Palazzo Ridolfi and the artistic legacy of Fra Bartolomeo. Your perfect Tuscan getaway starts here.

  • The Social Hub Florence Lavagnini: The Social Hub Florence Lavagnini is a vibrant 4-star hotel that appeals to adventurous spirits and business travellers alike. Located 1.6km from Santo Spirito, this hotel boasts a modern and lively atmosphere, perfect for those seeking a blend of work and play. Guests can enjoy a range of onsite adventure sports and recreational activities, making it an ideal choice for those looking to engage in exciting experiences while in Florence. With a guest rating of 9.0 out of 10, the hotel prides itself on providing both comfort and a unique environment to enhance your stay.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Just 1.3km from Santo Spirito, the B&B Hotel Firenze Pitti Palace al Ponte Vecchio is a charming 4-star accommodation tailored for families and adventurous travellers. With a guest rating of 9.0 out of 10, this hotel features amenities designed for children, such as babysitting services, ensuring a worry-free experience for parents. The nearby bicycle rental offers an exciting way to explore the historic streets of Florence, enhancing your family vacation with both fun and adventure.
  • Grand Hotel Cavour: Situated 1.6km from Santo Spirito, the Grand Hotel Cavour is a distinguished 4-star property, renowned for its family-friendly and pet-friendly environment. With a notable guest rating of 9.2 out of 10, the hotel provides a range of services for children, including in-room babysitting options. Pets are also welcome, allowing you to enjoy your vacation without leaving your furry companions behind. This hotel combines elegance with convenience, making it an excellent choice for families looking to explore the beauty of Florence.

Where to stay near Santo Spirito

Exploring Santo Spirito in Florence is a captivating experience that immerses you in the heart of the Florentine Renaissance. Wander through the charming Piazza Santo Spirito, where trendy cafés and artisan shops await. This neighbourhood offers a unique blend of history and modernity, with a friendly atmosphere perfect for romantic strolls or relaxing moments. Venture further afield to discover the beauty of Tuscany, making your visit both secluded and luxurious.

  • Florence: As the heart of Tuscany, Florence is a treasure trove of art and culture, with Santo Spirito nestled within its vibrant streets. The city experiences a steady influx of travellers year-round, with peak visits in March to April and September. Visitors flock to Florence for its rich cultural heritage, family-friendly activities, and bustling city atmosphere. Notably, the city's piazzas and historic sites, such as the Uffizi Gallery and the Ponte Vecchio, are a must-see. Florence also offers excellent shopping areas and relaxing spas, making it a versatile destination for all types of visitors.
  • Duomo: Located 1.4km from Santo Spirito, Duomo is one of Florence's most iconic neighbourhoods, famed for its stunning cathedral, the Santa Maria del Fiore. This area sees a moderate flow of tourists, particularly from July to September. Visitors are drawn to its cultural and city-themed experiences, with lively public markets and shopping areas that add to the local charm. The beautiful piazza squares and historic places in Duomo provide a picturesque backdrop for leisurely strolls and exploration, making it an essential stop for anyone visiting Florence.
  • San Giovanni: Just 1.4km from Santo Spirito, San Giovanni is another delightful neighbourhood steeped in history and culture. Similar to Duomo, it attracts visitors throughout the year, particularly during the summer months. San Giovanni is perfect for those seeking cultural experiences and family-friendly activities. The neighbourhood boasts a variety of shopping areas and bustling public markets, as well as scenic piazzas and historic landmarks that encapsulate the essence of Florence. This area offers a vibrant atmosphere, making it a great spot for immersing oneself in local life.

Things to do near Santo Spirito

Shopping

Santo Spirito offers a charming shopping experience with local boutiques and artisan shops. Explore the vibrant Mercato di Santo Spirito for handmade crafts and unique souvenirs. Nearby, the Oltrarno district features shops selling leather goods and traditional Tuscan products, perfect for finding special gifts to take home.

Recreation

Santo Spirito offers a range of wellness retreats, including yoga classes overlooking the Arno River and traditional Tuscan spa experiences featuring local olive oil treatments. You can also enjoy tranquil walks through the nearby gardens, immersing yourself in the rich art and culture of Florence.

Adventure

The Mugello Circuit, located 27.4km from Santo Spirito, offers an exhilarating motor racing experience amidst the stunning Tuscan landscape. Feel the adrenaline rush as you watch high-speed races or even participate in driving experiences tailored for thrill-seekers.

Nightlife

Santo Spirito buzzes with life after dark, featuring lively bars like the eclectic Caffè degli Artigiani, where you can enjoy local wines. For a more relaxed vibe, try Le Volpi e l'Uva, known for its charming atmosphere and fine selections. Each venue offers a unique taste of Florentine nightlife.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santo Spirito

Santo Spirito offers a delightful blend of culture and city experiences, making it perfect for outdoor vacations. Visitors can explore the charming Santo Spirito Square, admire the historic San Spirito church, and wander through the picturesque piazzas and palaces that define this vibrant area. With a focus on family-friendly activities, Santo Spirito is ideal for travellers seeking to immerse themselves in the rich heritage and local atmosphere of Florence.

  • Piazza del Duomo: This vibrant square serves as the heart of Florence, where you can immerse yourself in the city's cultural atmosphere. Surrounded by stunning architecture and lively cafés, it's an ideal spot for people-watching and enjoying local life.
  • Cathedral of Santa Maria del Fiore: Known for its striking dome designed by Brunelleschi, this iconic cathedral showcases exquisite artwork and intricate details. Visitors can climb to the dome for panoramic views of Florence, adding a touch of adventure to your cultural exploration.
  • Ponte Vecchio: This historic bridge is renowned for its charming shops and picturesque views over the Arno River. As you stroll along, you'll feel the rich history and artistry that have defined Florence for centuries.

Best time to go to Santo Spirito

The best time to visit Santo Spirito can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santo Spirito falls in July and August. August has moderately high visitor numbers and sunny weather. The coolest average temperature around Santo Spirito falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Reaching Santo Spirito in Florence is easily accomplished via three major airports. Florence (FLR-Peretola) is located 4.8km away, with luxurious hotels nearby, such as Bernini Palace and Palazzo Montebello, both offering various airport transportation options. Bologna (BLQ-Guglielmo Marconi) is 85.3km away, featuring the Grand Hotel Majestic and Starhotels Excelsior, which provide shuttle services. Lastly, Pisa (PSA-Galileo Galilei) is 67.6km from Santo Spirito, with excellent accommodations like the Bagni di Pisa Palace & Thermal Spa and Hotel Pisa Tower Plaza, both easily accessible from the airport. Each airport offers convenient access to the enchanting sights of Florence.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include La Torre Del Cestello and Palazzo Mannaioni Suites.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 502 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Favourite places to visit in the surrounding area include Piazza di Santa Maria Novella, Uffizi Gallery and Cathedral of Santa Maria del Fiore. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

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