Santo Spirito

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and notable monuments in this vibrant area.
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Things to do

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

S$96
per adult
92% of travellers recommend
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

S$43
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

S$163
per adult
100% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
Excursion to Pisa through the Tuscan Countryside

Florence: Pisa Tour through Tuscan Hills & Optional Tower Entry

S$87
per adult
88% of travellers recommend
Florence: Pisa Tour through Tuscan Hills & Optional Tower Entry
The Best of Tuscany in One Day Sightseeing Tour

The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery

S$100
per adult
98% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
Pizza and Gelato Class at a Farmhouse in Tuscany

PIZZA or PASTA and Gelato Class at a Farmhouse in Tuscany

S$100
per adult
96% of travellers recommend
PIZZA or PASTA and Gelato Class at a Farmhouse in Tuscany
See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
The price is S$184 per night from 18 Aug to 19 Aug
S$184
18 Aug - 19 Aug
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is S$162 per night from 12 Aug to 13 Aug
S$162
12 Aug - 13 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Cathedral of Santa ...
9/10 Wonderful! (287 reviews)
"I had a wonderful stay. The room was clean, spacious and comfortable. The location was convenient and a quick walk to the metro, attractions and many dining options. The room provided many extra amenities such as water, coffee and bathroom slippers. The air conditioning unit in my room was very weak ..."

Reviewed on 4 Aug, 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is S$141 per night from 30 Aug to 31 Aug
S$141
30 Aug - 31 Aug
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
UNA Hotels Vittoria Firenze
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
The price is S$124 per night from 9 Aug to 10 Aug
S$124
9 Aug - 10 Aug
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free Wi-Fi, 2 meeting rooms and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (233 reviews)
"Conveniently located. Monica was super helpful. I would definitely stay there again."

Reviewed on 20 Jul, 2026

Foresteria Valdese di Firenze - Casa per Ferie
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is S$209 per night from 8 Aug to 9 Aug
S$209
8 Aug - 9 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,152 reviews)
"We loved this apartment! The staff were friendly and helpful, suggesting places to eat and ordering taxis to the train station. The apartment was perfect for what we wanted - would highly recommend and would absolutely stay here again"

Reviewed on 5 Aug, 2026

Palazzo Mannaioni Suites
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI
Stay at this hostel in Florence. Enjoy free Wi-Fi, daily housekeeping and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza della ...
7.8/10 Good! (64 reviews)
"No"

Reviewed on 30 Jul, 2026

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Hostel Santa Monaca
See all 525 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Piazza della Signoria are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito