⭐ Top 10 Hotels Near Mayo Clinic Scottsdale for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

Michael

S$156

includes taxes & fees

11 Oct - 12 Oct

A cluster of modern, multi-story buildings with a river in the foreground.

A golf course with a pond, a clubhouse, and a hilly backdrop.

A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

A dining area with a glass table, wooden chairs, and potted plants.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Shelby

S$193

includes taxes & fees

25 Oct - 26 Oct

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel room with a sofa, a desk, a chair, a bed, and a door leading to another room.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Paul

S$123

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk with a chair, a TV, and a lamp.

A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

William

S$159

includes taxes & fees

1 Nov - 2 Nov

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A modern lobby with a brick wall, seating area, and a flat-screen TV.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

5. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

greg

S$186

includes taxes & fees

12 Oct - 13 Oct

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

6. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

S$159

includes taxes & fees

7 Oct - 8 Oct

A hotel room with two beds, a TV, a desk, and a window with a view.

A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

7. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herlyn

S$125

includes taxes & fees

12 Oct - 13 Oct

A living room with a sofa, a coffee table, and a kitchen area with a refrigerator and microwave.

A row of single-story buildings with a parking lot in between, surrounded by palm trees.

A bedroom with a bed, a lamp, an air conditioning unit, and curtains.

A room with a red chair, a wooden cabinet with a television, and a large mirror on the wall.

8. Starlite Motel

19 km from Mayo Clinic Scottsdale

Virginia

S$119

includes taxes & fees

9 Oct - 10 Oct

An outdoor dining table set with chairs, string lights, and a sunset view.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.

A modern lobby with a seating area, a kitchen, and a reception desk.

9. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Damon

S$227

includes taxes & fees

1 Nov - 2 Nov

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Ioana G

S$149

includes taxes & fees

7 Oct - 8 Oct

An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.

A lounge area with a grand piano, blue seating, and a stone wall.

A golf course with a mountain backdrop, surrounded by desert vegetation.

11. Wekopa Casino Resort

10.3 km from Mayo Clinic Scottsdale

jennifer

S$235

includes taxes & fees

7 Oct - 8 Oct

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

12. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Meghan Rebbecca

S$365

includes taxes & fees

7 Oct - 8 Oct

A modern outdoor seating area with sofas and a central fire feature.

A modern hotel lobby with a white sofa, armchairs, a coffee table, and a dining area with chairs and a table. Large windows provide a view of the outdoors.

A modern hotel with a prominent entrance, multiple floors, and a clear sky.

A hotel lobby with a tiled floor, a large chandelier, and a sign for the Arizona Ballroom.

13. Delta Hotels by Marriott Phoenix Mesa

18.7 km from Mayo Clinic Scottsdale

James

S$156

includes taxes & fees

19 Oct - 20 Oct

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

14. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Maria Antoinette

S$224

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

A hotel breakfast area with a self-serve station, seating, and a trash bin.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and palm trees.

15. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

S$140

includes taxes & fees

26 Oct - 27 Oct

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

A pool area with a rock formation, palm trees, and lounge chairs.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

16. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Tammie

S$146

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with round tables and chairs, a pool in the background, and a covered seating area.

A hotel reception area with a large bridge mural, a reception desk, and a snack bar.

A hotel room with a desk, a bed, a TV, a sofa, a small table, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a sofa, a small table, and a TV.

17. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Gentry

S$241

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

A breakfast buffet with various food items and a coffee machine.

An outdoor patio with a grill, table, and chairs.

A reception area with a counter, two armchairs, and a round table.

18. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

Michael

S$198

includes taxes & fees

14 Oct - 15 Oct

A spacious lobby with a modern design, featuring a curved ceiling, a stone wall, and a seating area with a patterned rug.

A bar area with a curved counter, multiple stools, and a sign reading "The Curve".

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A hotel room with a large window offering a view of a body of water and palm trees, a desk with a chair, and a round mirror on the wall.

19. Sheraton Mesa Hotel at Wrigleyville West

18.9 km from Mayo Clinic Scottsdale

Blanca

S$210

includes taxes & fees

1 Nov - 2 Nov

A modern hotel with a brick facade, large windows, and a covered entrance area.

A modern lobby with a sectional sofa, a round coffee table, and a mural on the wall.

A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.

An outdoor patio area with round tables and chairs, a fire pit, and a large umbrella.

20. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Marie

S$200

includes taxes & fees

11 Oct - 12 Oct

View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property	Property class	Guest rating
Sonesta Select Scottsdale at Mayo Clinic Campus	8.4 Very good 1,086 reviews	View
Inn at Eagle Mountain	9.0 Wonderful 1,026 reviews	View
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale	8.8 Excellent 1,854 reviews	View
Comfort Suites Scottsdale Talking Stick Entertainment District	9.2 Wonderful 2,032 reviews	View
Hyatt Place Phoenix/Mesa	9.2 Wonderful 2,007 reviews	View

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

8/10 Good

"It’s a non smoking hotel and the people next to us were smoking cigarettes that you could smell it down the whole floor. We talked to a few people about it and they did nothing. I guess if we really complained about it we maybe would if gotten a different room. But liked the room we were in so we just sucked it up."

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

8/10 Good

"The dining room was very clean and nice but the hallways to the rooms were not vacuumed it seemed and the elevators appeared kind of dirty."

Home2 Suites by Hilton Scottsdale Salt River

8/10 Good

"Love the lay out of the room. Very clean also. Food was good except for the milk inside the fridge, i think it was all expired. The guy informed the staff about it. The dining area was very warm, or the AC was off?? Staff was very friendly."

Spark by Hilton Fountain Hills Scottsdale

10/10 Excellent

"It was a comfortable stay."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"The price was excellent for where it was. I have stayed here two different times and will stay again. The staff was very accommodating as well. The rooms are only cleaned during your stay if you request it. You can ask for extra towels as well. This doesn't bother me at all and wasnt a problem."

Wekopa Casino Resort

10/10 Excellent

"Wonderful resort!"

Aiden by Best Western Scottsdale North

8/10 Good

"Staff & Breakfast were Great! 😃"

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"Best free breakfast I have experienced. Rooms were clean."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 22 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodation options within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available near Mayo Clinic Scottsdale.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain or SunRidge Canyon Golf Club are some local sights worth checking out.

Hotels near Mayo Clinic Scottsdale

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

4. Comfort Suites Scottsdale Talking Stick Entertainment District

5. Hyatt Place Phoenix/Mesa

6. Fountain Park Hotel, BW Signature Collection

7. Spark by Hilton Fountain Hills Scottsdale

8. Starlite Motel

9. Home2 Suites by Hilton Mesa Longbow, AZ

10. Aiden by Best Western Scottsdale North

11. Wekopa Casino Resort

12. Talking Stick Resort

13. Delta Hotels by Marriott Phoenix Mesa

14. Embassy Suites by Hilton Phoenix Scottsdale

15. Holiday Inn Express Scottsdale North by IHG

16. Westgate Painted Mountain Golf Resort

17. Staybridge Suites Scottsdale - Talking Stick by IHG

18. Sonesta ES Suites Scottsdale Paradise Valley

19. Sheraton Mesa Hotel at Wrigleyville West

20. Springhill Suites Phoenix Scottsdale Marriott

Compare popular hotels close to Mayo Clinic Scottsdale

Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Home2 Suites by Hilton Scottsdale Salt River

Spark by Hilton Fountain Hills Scottsdale

Fountain Park Hotel, BW Signature Collection

Wekopa Casino Resort

Aiden by Best Western Scottsdale North

Staybridge Suites Scottsdale - Talking Stick by IHG

Frequently asked questions

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