South Main

Houston

Photo by Hazem Abdul

Popular places to visit

Things to do


Top hotels in South Main

Comfort Suites near Texas Medical Center - NRG Stadium
Comfort Suites near Texas Medical Center - NRG Stadium
2.5 out of 5
1055 Mcnee Rd, Houston, TX
The price is S$148 per night from 22 Jun to 23 Jun
S$148
22 Jun - 23 Jun
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (909 reviews)
"Everything was very clean and the room was pretty nice. Priced well."

Reviewed on 9 Jun, 2025

Comfort Suites near Texas Medical Center - NRG Stadium
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
The price is S$161 per night from 15 Jun to 16 Jun
S$161
15 Jun - 16 Jun
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,399 reviews)
Different type of hotel - high tech.
"We have traveled a lot in Europe and this hotel reminds us of a European hotel. Just different in many ways. Friendly and helpful staff. Good price for location relatively close to ball park but not much for restaurants."

Reviewed on 6 Jun, 2025

Club Quarters Hotel Downtown, Houston
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel
4 out of 5
1100 Texas St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is S$194 per night from 15 Jun to 16 Jun
S$194
15 Jun - 16 Jun
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,008 reviews)
"The staff was extraordinary and the property was exquisitely clean."

Reviewed on 8 Jun, 2025

Magnolia Hotel Houston, A Tribute Portfolio Hotel
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
4.5 out of 5
6633 Travis St, Houston, TX
The price is S$156 per night from 30 Jun to 1 Jul
S$156
30 Jun - 1 Jul
includes taxes & fees
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,377 reviews)
"We spent the night before a surgery and this was a very pleasant and very close to the hospital place to stay, as noted in a bad review the pool area still appears to be closed but we weren’t here for that. We would absolutely stay here again."

Reviewed on 7 Jun, 2025

Hilton Houston Plaza/Medical Center
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
The price is S$243 per night from 4 Jul to 5 Jul
S$243
4 Jul - 5 Jul
includes taxes & fees
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,290 reviews)
"Great place to stay"

Reviewed on 7 Jun, 2025

Hilton Americas-Houston
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
The price is S$170 per night from 3 Jul to 4 Jul
S$170
3 Jul - 4 Jul
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,479 reviews)
"The staff was very friendly and Kelvin checked on us every day!"

Reviewed on 5 Jun, 2025

The Whitehall Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

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Astrodome

4/5(1 area review)

While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.

Astrodome
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Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Texas Medical Center
Hermann Park which includes a park and landscape views

Houston Museum District

Known for its abundant dining options and interesting museums, there's plenty to explore in Houston Museum District. Top attractions like Houston Zoo and Children's Museum of Houston are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.

Houston Museum District
Hermann Park which includes a park and landscape views

South Central Houston

3/5(1 area review)

If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

South Central Houston
Menil Collection featuring interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Montrose
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The Galleria

4.5/5(15 area reviews)

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

The Galleria

South Main