South Main
Houston
Visit South Main
Popular places to visit
NRG Stadium
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the great live music and lively festivals in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and great live music in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed art galleries and entertainment choices in this vibrant area.
Space Center Houston
Visit the heart of the American space industry in the control centre that put man on the moon.
Things to do
Space Center Houston Admission Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center
Houston: Holocaust Museum Houston Entry Ticket
Houston: Children's Museum Houston Entry Ticket
Top hotels in South Main
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
We've stayed here several times. I like how convenient and walkable the location is. The staff has always been super welcoming at check-in, which I appreciate.
Reviewed on 12 Jan, 2026
Club Quarters Hotel Downtown, Houston
Staff were nice and room was decent. Only complaint is we asked for a fridge and got one that wasn't working
Reviewed on 11 Jan, 2026
Hilton Houston Plaza/Medical Center
Clean room
Reviewed on 12 Jan, 2026
Blossom Hotel Houston, Curio Collection by Hilton
Great time
Reviewed on 12 Jan, 2026
The Whitehall Houston
Yes! The rooms were clean and service was amazing!
Reviewed on 12 Jan, 2026
The Royal Sonesta Houston Galleria
Great stay
Reviewed on 13 Jan, 2026
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Continental Club or Midtown Arts and Theater Center Houston and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
