Hotels in South Main
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Our top choices for South Main hotels
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.0 out of 10, Good, (1,287 reviews)
"Hotel clean and convenient "
Mitzi
The price is S$135
includes taxes & fees
26 Apr - 27 Apr
Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,008 reviews)
"Great location"
Jeremy
The price is S$118
includes taxes & fees
20 Apr - 21 Apr
Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,001 reviews)
"Courteous staff, clean room, quite property"
Javier
The price is S$100
includes taxes & fees
10 May - 11 May
Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (848 reviews)
"Room was clean. It had a musty smell though. "
Ryan
The price is S$116
includes taxes & fees
12 Apr - 13 Apr
Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.6 out of 10, Excellent, (1,014 reviews)
"Close and convenient to NRG."
Cynthia
The price is S$174
includes taxes & fees
10 May - 11 May
Hotel Royale
Hotel Royale20.9 km from South Main
9.4 out of 10, Exceptional, (23 reviews)
"Room was very clean and convenient for my short stay. Would recommend for business trips. "
Jerome
The price is S$109
includes taxes & fees
11 Apr - 12 Apr
Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
9.2 out of 10, Wonderful, (210 reviews)
"Yes very great place"
Lloyd
The price is S$133
includes taxes & fees
5 May - 6 May
Best Western Plus Manvel Inn & Suites
Best Western Plus Manvel Inn & Suites22.6 km from South Main
8.8 out of 10, Excellent, (774 reviews)
"Everything about this place was awesome. Will definitely be staying there again on my next trip!!!!!"
Penny
The price is S$115
includes taxes & fees
22 Apr - 23 Apr
GreenTree Hotel & Extended Stay I-10 FWY Houston, Channelview, Baytown
GreenTree Hotel & Extended Stay I-10 FWY Houston, Channelview, Baytown28.8 km from South Main
8.6 out of 10, Excellent, (673 reviews)
"Great stay for the price "
Angela
The price is S$79
includes taxes & fees
3 May - 4 May
Tru by Hilton Houston Webster NASA
Tru by Hilton Houston Webster NASA30.7 km from South Main
9.0 out of 10, Wonderful, (1,001 reviews)
"Clean and courteous staff."
chris
The price is S$128
includes taxes & fees
10 May - 11 May
Crystal Inn Northeast Houston Downtown I-610
Crystal Inn Northeast Houston Downtown I-610Northside, 18.9 km from South Main
8.2 out of 10, Very good, (140 reviews)
"Nice place "
Ramon
The price is S$91
includes taxes & fees
27 Apr - 28 Apr
Palace Inn Blue 290 W 43rd & Bingle Rd
Palace Inn Blue 290 W 43rd & Bingle Rd19.4 km from South Main
9.6 out of 10, Exceptional, (29 reviews)
"loveeeee. so cute came here for spring break. comfy little spot definitely recommend!"
Danielle
The price is S$130
includes taxes & fees
10 Apr - 11 Apr
Hotel Park Place
Hotel Park PlaceSoutheast Houston, 12.1 km from South Main
8.8 out of 10, Excellent, (306 reviews)
"Super clean, nice staff, convenient location"
Russell
The price is S$86
includes taxes & fees
27 Apr - 28 Apr
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
La Quinta Inn & Suites by Wyndham Houston Bush IAH South31.2 km from South Main
8.2 out of 10, Very good, (1,785 reviews)
"The staff was very helpful and made our stay enjoyable."
cynthia
The price is S$136
includes taxes & fees
15 Apr - 16 Apr
GreenTree Inn Houston IAH Airport
GreenTree Inn Houston IAH Airport31.4 km from South Main
6.6 out of 10, (1,088 reviews)
"The check in staff was very helpful and nice. The place looks a bit dated and like it’s had a lot of traffic but it was decent and the price was great. "
Royce
The price is S$81
includes taxes & fees
11 Apr - 12 Apr
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Hampton Inn & Suites Houston-Bush Intercontinental Aprt31.8 km from South Main
8.8 out of 10, Excellent, (1,830 reviews)
"Clean room and courteous staff. "
Sarah
The price is S$140
includes taxes & fees
8 May - 9 May
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham
Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham18.5 km from South Main
8.8 out of 10, Excellent, (1,139 reviews)
"Great breakfast and staff was wonderful."
Jeffery
The price is S$123
includes taxes & fees
14 Apr - 15 Apr
Sonesta Simply Suites Houston – NASA Clear Lake
Sonesta Simply Suites Houston – NASA Clear Lake31.8 km from South Main
8.0 out of 10, Very good, (1,008 reviews)
"Clean rooms , friendly staff "
Heather
The price is S$70
includes taxes & fees
16 Apr - 17 Apr
Houston Marriott South at Hobby Airport
Houston Marriott South at Hobby AirportSoutheast Houston, 15.7 km from South Main
8.8 out of 10, Excellent, (1,449 reviews)
"Staff was very nice, rooms were very clean"
Tami
The price is S$128
includes taxes & fees
11 Apr - 12 Apr
Four Points by Sheraton Houston Intercontinental Airport
Four Points by Sheraton Houston Intercontinental Airport29.9 km from South Main
8.4 out of 10, Very good, (1,001 reviews)
"Very clean, and polite staff, easy to find airport shuttle."
DONGBIN
The price is S$125
includes taxes & fees
8 May - 9 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Main
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Comfort Suites Houston near Medical Center- NRG Stadium | 8.6 Excellent 1,014 reviews | View | ||||||
 Candlewood Suites Houston Medical Center by IHG | 7.4 Good 848 reviews | View | ||||||
 Wyndham Houston near NRG Park/Medical Center | 7.0 Good 1,287 reviews | View | ||||||
 Wingate Houston near NRG Park/Medical Center | 6.6 1,008 reviews | View | ||||||
 Quality Inn & Suites NRG Park - Medical Center | 6.6 1,001 reviews | View |
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Top South Main Hotel Reviews
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
8/10 Good
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- Children's Museum of Houston
- Daikin Park
- Downtown Aquarium
- George R. Brown Convention Center
- Visit Downtown Houston
- Visit Foster Place
- Houston Methodist Hospital
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- Visit River Oaks
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- Houston Zoo
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- Menil Collection
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- Nature Discovery Center
- Uptown Park
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