South Main

Houston

A city skyline with modern buildings and a park with a lake.
A modern urban street with a metro train, buildings, and a clear blue sky.

Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

S$38
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center

Houston Museum of Natural Science: Butterfly Center Ticket

S$19
per adult
100% of travellers recommend
Houston Museum of Natural Science: Butterfly Center Ticket
Viral Drip Bear Painting w/ RnB & Hip Hop Tunes

Viral Drip Bear Painting w/ RnB & Hip Hop Tunes

S$57
per adult
Viral Drip Bear Painting w/ RnB & Hip Hop Tunes
Houston: Guided City Tour by an Open-Top Double Decker Bus

Houston: Guided City Tour by an Open-Top Double Decker Bus

S$51
per adult
98% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
HOP ON- HOP OFF

Houston's Official City & Mural Tour!

S$51
per adult
88% of travellers recommend
Houston's Official City & Mural Tour!
Houston: Holocaust Museum Houston Entry Ticket

Houston: Holocaust Museum Houston Entry Ticket

S$28
per adult
90% of travellers recommend
Houston: Holocaust Museum Houston Entry Ticket
See all activities in Houston

Top hotels in South Main

Wyndham Houston at Reliant Park & Medical Center

Wyndham Houston at Reliant Park & Medical Center

3.5 out of 5
8686 Kirby Drive Houston TX
The price is S$147 per night from 14 Oct to 15 Oct
S$147
14 Oct - 15 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, a 24-hour fitness centre and a 24-hour front desk. Our guests praise the helpful staff and ...
7.2/10 Good! (1,436 reviews)
"The room was clean and the hotel was within walking distance to the event."

Reviewed on 7 Oct, 2026

Wyndham Houston at Reliant Park & Medical Center
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
The price is S$146 per night from 18 Oct to 19 Oct
S$146
18 Oct - 19 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ...
8.6/10 Excellent! (4,510 reviews)
"Second time staying. Always a pleasure. Walking distance to the ballpark"

Reviewed on 6 Oct, 2026

Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
The price is S$203 per night from 15 Oct to 16 Oct
S$203
15 Oct - 16 Oct
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
The price is S$203 per night from 21 Oct to 22 Oct
S$203
21 Oct - 22 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
The Whitehall Houston
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
The price is S$122 per night from 18 Oct to 19 Oct
S$122
18 Oct - 19 Oct
includes taxes & fees
Stay at this family-friendly hotel in Houston. Enjoy free Wi-Fi, an outdoor pool and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
Grand Tuscany Hotel
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 out of 5
13210 Katy Fwy Houston TX
The price is S$142 per night from 7 Nov to 8 Nov
S$142
7 Nov - 8 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the restaurant and the helpful staff ...
8.6/10 Excellent! (1,690 reviews)
"This is an older luxury hotel, so not the most modern fixtures and carpet, but everything was spotless and well maintained. There are many amenities on site, like an excellent whiskey bar and large gift/coffee shop. Close to many restaurants, great west side location. Staff friendly and helpful, ..."

Reviewed on 7 Oct, 2026

Hyatt Regency Houston West
See all 7,417 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

South Main