Photo by Bill Dillard

Hotels with connecting rooms in Southeast Missouri

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Hotels with connecting rooms

Our top choices for Southeast Missouri hotels with connecting rooms

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"Great place and staff, very accommodating!"
United States
Megan
The price is S$131
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Front of property
The Farmstead Hotel

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (463)
"Nice place "
United States
Debbie
The price is S$126
includes taxes & fees
16 Dec - 17 Dec
The Farmstead Hotel
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is S$113
includes taxes & fees
16 Dec - 17 Dec
Drury Inn & Suites Jackson MO
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (702)
"Amazing place"
United States
Mladen
The price is S$147
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Poplar Bluff by IHG
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (964)
"Nice room helpful staff. "
United States
Deborah
The price is S$137
includes taxes & fees
20 Dec - 21 Dec
Drury Inn & Suites Poplar Bluff
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (854)
"Very clean, great check in"
United States
Teresa
The price is S$152
includes taxes & fees
4 Jan - 5 Jan, 2026
Fairfield Inn & Suites by Marriott Poplar Bluff
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1003)
"Easy parking , quiet and comfortable bed , we’ll stop again on our way back "
United States
joseph
The price is S$105
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Sikeston
Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (540)
"Clean room and pleasant staff"
United States
David
The price is S$129
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Perryville by IHG
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is S$102
includes taxes & fees
20 Dec - 21 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Business centre
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1005)
"Room was clean , staff was friendly !"
United States
Sally
The price is S$79
includes taxes & fees
22 Dec - 23 Dec
Baymont Inn and Suites by Wyndham Farmington, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Very friendly staff and great breakfast"
Ray 1-night trip
Posted 6 days ago
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean room and spacious "
Belinda 1-night trip
Posted 8 days ago
Drury Inn & Suites Sikeston, MO

Explore a world of travel with Expedia

Frequently asked questions

How much do hotels with connecting rooms in Southeast Missouri cost?
Expect to pay somewhere from S$79 to S$152 per night for hotels with connecting rooms in Southeast Missouri. Whatever your budget, an epic stay is a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best hotels with connecting rooms in Southeast Missouri?
There are multiple hotels with connecting rooms in Southeast Missouri with a total average guest review rating of 8.9, so you're sure to snag the perfect place for you. If you're basing yourself in Cape Girardeau, check out Drury Plaza Hotel Cape Girardeau Conference Centre. This popular 3-star hotel comes with connecting rooms, a swimming pool and complimentary breakfast. Travellers also recommend Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel. This 2.5-star Cape Girardeau escape offers pillow top mattresses and a swimming pool.
How many hotels with adjoining rooms are there in Southeast Missouri?
Take a look at our 24 hotels with adjoining rooms in Southeast Missouri and lock in your favourite. Whether you're planning a family trip or reuniting with friends, Expedia has got you covered.
Are there any family-friendly hotels with connecting rooms in Southeast Missouri?
Definitely, so gather the whole family and organise your Southeast Missouri getaway! If Cape Girardeau is on your list of places to visit, consider a stay at Drury Plaza Hotel Cape Girardeau Conference Centre. This 3-star option is a popular family-friendly hotel with connecting rooms. It also comes with complimentary breakfast and housekeeping services. Another great choice is Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel. Also in Cape Girardeau, it has a 2.5-star rating and includes a nearby zoo, complimentary breakfast and connecting rooms. You'll discover lots of fabulous things to do with the family in Cape Girardeau. Cape Splash Family Aquatic Centre and Lazy L Safari Park deliver a fantastic day out.
Why book your hotel with connecting rooms in Southeast Missouri with Expedia?
With Expedia, it's easy to find your dream hotel with connecting rooms in Southeast Missouri. Travelling with the family? Try out our filters to search for properties with a pool or free WiFi. If you have a budget, click on how much you'd like to spend and the preferred star rating of your hotel. We'll help you find the perfect fit whatever your style of travel or plans.
How can I find cheap hotels with connecting rooms in Southeast Missouri?
A good way to spot cheap hotels with connecting rooms in Southeast Missouri is with Expedia's convenient filter tool. Narrow down your search results by star rating, budget and amenities to secure awesome prices with only a few clicks.
What is there to do in Southeast Missouri near my hotel with connecting rooms?
The best travel accessory for your Southeast Missouri adventure is an epic itinerary! Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site are among the top things to do if you're visiting Cape Girardeau. Ste Genevieve also has plenty of fantastic attractions, such as Sainte Genevieve Winery. In the mood to explore more? Carve out some time for Bolduc House Museum and Felix Valle House State Historic Site too.