TOP Luxury Hotels in Southeast Missouri for 2026 - 𝗙𝗿𝗲𝗲 𝗖𝗮𝗻𝗰𝗲𝗹𝗹𝗮𝘁𝗶𝗼𝗻 on Select Hotels | Expedia Singapore

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Check availability on Southeast Missouri Luxury Hotels

Tonight

6 Sept - 7 Sept

Tomorrow

7 Sept - 8 Sept

Next weekend

11 Sept - 13 Sept

In two weeks

18 Sept - 20 Sept

Our top choices for Southeast Missouri luxury hotels

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

1. The Riverview

Cape Girardeau

S$152

includes taxes & fees

7 Sept - 8 Sept

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

A large hotel with a prominent "RIVER CITY" sign.

A casino with multiple gaming tables and slot machines.

A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.

2. River City Casino & Hotel

St. Louis

S$171

includes taxes & fees

4 Oct - 5 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

A spa bath with a sign indicating a capacity of 8 persons.

3. Drury Plaza Hotel St. Louis Brentwood

Brentwood

S$204

includes taxes & fees

13 Sept - 14 Sept

A brick building with a tower, large windows, and a fountain in the garden.

A grand staircase with a curved design, leading to an upper floor.

A pool area with lounge chairs and umbrellas, a clear blue pool, and a building with a dome in the background.

A grand lobby with a chandelier, a staircase, and a central table with a floral arrangement.

4. Hilton St. Louis Frontenac

Frontenac

Upscale St. Louis retreat features pool, concierge, fine dining in prime business district.

S$217

includes taxes & fees

13 Sept - 14 Sept

View all properties

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Nice place! Breakfast was amazing!"

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

8/10 Good

"Bed was very comfortable . No water pressured for shower"

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

8/10 Good

"room was clean and the front staff was nice. place served it's purpose (stayed for only 2 nights). Not much amenitites."

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